Polymer nanomedicines with enzymatically triggered activation: A comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure

Autor: Pechar, Michal, Pola, Robert, Studenovský, Martin, Bláhová, Markéta, Grosmanová, Eliška, Dydowiczová, Aneta, Filipová, Marcela, Islam, Rayhanul, Gao, Shanghui, Fang, Jun, Etrych, Tomáš

Publikováno v: In Nanomedicine: Nanotechnology, Biology, and Medicine November 2022 46

Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing.

Autor: Basu, Amrita¹ (AUTHOR), Dydowiczová, Aneta¹ (AUTHOR), Trosko, James E.² (AUTHOR), Bláha, Luděk¹ (AUTHOR), Babica, Pavel¹ (AUTHOR)

Publikováno v: Toxicology Mechanisms & Methods. Oct2020, Vol. 30 Issue 8, p590-604. 15p. 2 Color Photographs, 2 Black and White Photographs, 2 Diagrams, 2 Graphs, 1 Map.

Fully synthetic, tunable poly( α -amino acids) as the base of bioinks curable by visible light.

Autor: Golunova A; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Dvořáková J; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Velychkivska N; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Strachota B; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Dydowiczová A; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Trousil J; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic., Proks V; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech Republic.

Publikováno v: Biomedical materials (Bristol, England) [Biomed Mater] 2024 Apr 26; Vol. 19 (3). Date of Electronic Publication: 2024 Apr 26.

The transmission and toxicity of polymer-bound doxorubicin-containing exosomes derived from human adenocarcinoma cells

Autor: Kristýna Gunár, Lenka Kotrchová, Marcela Filipová, Tereza Krunclová, Aneta Dydowiczová, Robert Pola, Eva Randárová, Tomáš Etrych, Olga Janoušková

Publikováno v: Nanomedicine (London, England). 17(19)

Background: Exosomes are extracellular vesicles with the ability to encapsulate bioactive molecules, such as therapeutics. This study identified a new exosome mediated route of doxorubicin and poly(N-(2-hydroxypropyl)methacrylamide) (pHPMA)-bound dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9109d34fd7be53f028e9c192b670c719
https://pubmed.ncbi.nlm.nih.gov/36255034

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