Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup.

Autor: Weckel A; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Dhariwala MO; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Ly K; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA; University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA., Tran VM; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA; University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA., Ojewumi OT; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Riggs JB; University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA., Gonzalez JR; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA; University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA., Dwyer LR; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA; University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA., Okoro JN; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Leech JM; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Bacino MS; University of California, San Francisco, Oral and Craniofacial Sciences Graduate Program, San Francisco, CA 94143, USA., Cho GD; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA; University of California, Los Angeles, Department of Infectious Diseases, Los Angeles, CA 90095, USA., Merana G; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA., Anandasabapathy N; Department of Dermatology, Meyer Cancer Center, Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Medical College, New York, NY, USA., Kumamoto Y; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA; Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., Scharschmidt TC; University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA. Electronic address: tiffany.scharschmidt@ucsf.edu.

Publikováno v: Immunity [Immunity] 2023 Jun 13; Vol. 56 (6), pp. 1239-1254.e7. Date of Electronic Publication: 2023 Apr 06.

Intestinal inflammation alters the antigen-specific immune response to a skin commensal.

Autor: Merana GR; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA., Dwyer LR; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA., Dhariwala MO; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA., Weckel A; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA., Gonzalez JR; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA., Okoro JN; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA., Cohen JN; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA., Tamaki CM; Parnassus Flow Cytometry CoLab, University of California, San Francisco, San Francisco, 94143, USA., Han J; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Tasoff P; Benioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA., Palacios-Calderon Y; City College of San Francisco, San Francisco, CA 94112, USA., Ha CWY; Benioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA., Lynch SV; Benioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Segre JA; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Kong HH; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Kattah MG; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Ma A; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Scharschmidt TC; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: tiffany.scharschmidt@ucsf.edu.

Publikováno v: Cell reports [Cell Rep] 2022 May 31; Vol. 39 (9), pp. 110891.