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mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8+ T and NK Cells to Generate Antitumor Immunity.

Autor: Nirschl CJ; Werewolf Therapeutics, Watertown, Massachusetts., Brodkin HR; Werewolf Therapeutics, Watertown, Massachusetts., Domonkos C; Werewolf Therapeutics, Watertown, Massachusetts., Dwyer CJ; Werewolf Therapeutics, Watertown, Massachusetts., Hicklin DJ; Werewolf Therapeutics, Watertown, Massachusetts., Ismail N; Werewolf Therapeutics, Watertown, Massachusetts., Seidel-Dugan C; Werewolf Therapeutics, Watertown, Massachusetts., Steiner P; Werewolf Therapeutics, Watertown, Massachusetts., Steuert Z; Werewolf Therapeutics, Watertown, Massachusetts., Sullivan JM; Werewolf Therapeutics, Watertown, Massachusetts., Winston WM; Werewolf Therapeutics, Watertown, Massachusetts., Salmeron A; Werewolf Therapeutics, Watertown, Massachusetts.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2023 Jul 05; Vol. 11 (7), pp. 962-977.

B cells imprint adoptively transferred CD8 ⁺ T cells with enhanced tumor immunity.

Autor: Smith AS; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA aubrey.s.smith@emory.edu chrystal.mary.paulos@emory.edu.; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Knochelmann HM; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA.; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Wyatt MM; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Rangel Rivera GO; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA.; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Rivera-Reyes AM; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Dwyer CJ; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA., Ware MB; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Cole AC; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA., Neskey DM; Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.; Department of Cell and Molecular Pharmacology and Developmental Therapeutics, Medical University of South Carolina, Charleston, South Carolina, USA., Rubinstein MP; Division of Medical Oncology, The Ohio State University, Columbus, Ohio, USA., Liu B; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA., Thaxton JE; Department of Cell Biology & Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Immunotherapy Program, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bartee E; Department of Internal Medicine, Division of Molecular Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA., Paulos CM; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA aubrey.s.smith@emory.edu chrystal.mary.paulos@emory.edu.; Division of Surgical Oncology, Department of Surgery, Emory University, Atlanta, Georgia, USA.; Department of Microbiology and Immunology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jan; Vol. 10 (1).

Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients.

Autor: Janneh AH; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Kassir MF; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Dwyer CJ; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Surgery, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Chakraborty P; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Surgery, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Pierce JS; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Flume PA; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Medicine, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Li H; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Public Health Sciences, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Nadig SN; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Surgery, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Mehrotra S; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA.; Department of Surgery, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Ogretmen B; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA. ogretmen@musc.edu.; Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA. ogretmen@musc.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jul 09; Vol. 11 (1), pp. 14232. Date of Electronic Publication: 2021 Jul 09.