Revitalizing antimicrobial strategies: paromomycin and dicoumarol repurposed as potent inhibitors of M.tb's replication machinery via targeting the vital protein DnaN.

Autor: Ali W; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India. Electronic address: waseemali_sch@jamiahamdard.ac.in., Agarwal M; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India. Electronic address: drmeetuagarwal@jamiahamdard.ac.in., Jamal S; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India., Gangwar R; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India., Sharma R; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India. Electronic address: rahulsharma_sch@jamiahamdard.ac.in., Mubarak MM; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad 201002, India; Clinical Microbiology and PK-PD Division, CSIR-IIIM, Sanatnagar, Srinagar, J&K, India., Wani ZA; Clinical Microbiology and PK-PD Division, CSIR-IIIM, Sanatnagar, Srinagar, J&K, India., Ahmad Z; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad 201002, India; Clinical Microbiology and PK-PD Division, CSIR-IIIM, Sanatnagar, Srinagar, J&K, India; Council of Scientific & Industrial Research (CSIR), Professor Academy of Scientific & Innovative Research (AcSIR), India. Electronic address: zahoorap@iiim.res.in., Khan A; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India., Sheikh JA; Jamia Hamdard, Department of Biotechnology, New Delhi 110062, India. Electronic address: jasheikh@jamiahamdard.ac.in., Grover A; Jawaharlal Nehru University, School of Biotechnology, New Delhi 110067, India. Electronic address: agrover@mail.jnu.ac.in., Bhaskar A; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India. Electronic address: ashima@icgeb.res.in., Dwivedi VP; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India. Electronic address: ved@icgeb.res.in., Grover S; Jamia Hamdard, Department of Molecular Medicine, New Delhi 110062, India. Electronic address: sonamgrover@jamiahamdard.ac.in.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 3), pp. 134652. Date of Electronic Publication: 2024 Aug 22.

Immunoinhibitory effects of anti-tuberculosis therapy induce the host vulnerability to tuberculosis recurrence.

Autor: Pahuja I; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.; Department of Molecular Medicine, Jamia Hamdard University, New Delhi, India., Ghoshal A; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Okieh AA; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Verma A; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Negi K; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Agarwal M; Department of Molecular Medicine, Jamia Hamdard University, New Delhi, India., Chandra NS; Department of Microbiology, Ram Lal Anand College, University of Delhi, New Delhi, India., Sharma SK; School of Computer & Systems Sciences, Jawaharlal Nehru University, New Delhi, India., Bhaskar A; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Dwivedi VP; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2024 Jul 02; Vol. 12 (7), pp. e0041224. Date of Electronic Publication: 2024 May 29.

Author Correction: Novel peptide inhibitor of human tumor necrosis factor-α has antiarthritic activity.

Autor: Sahu D; Product Development Cell, National Institute of Immunology, New Delhi, India. debasissahu.phd@gmail.com.; Department of Orthopedics Surgery, New York University School of Medicine, New York, NY, USA. debasissahu.phd@gmail.com.; Science Habitat, Ubioquitos Inc, London, ON, Canada. debasissahu.phd@gmail.com., Gupta C; School of Biomedical Sciences, Galgotias University, Greater Noida, UP, India.; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Yennamalli RM; Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed to Be University, Thanjavur, Tamil Nadu, India., Sharma S; Amity Institute of Forensic Sciences, Amity University, Noida, Uttar Pradesh, India.; Science Habitat, Ubioquitos Inc, London, ON, Canada., Roy S; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Hasan S; Department of Orthopedics Surgery, New York University School of Medicine, New York, NY, USA., Gupta P; Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, Maharashtra, India., Sharma VK; Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, Punjab, India., Kashyap S; Division of Pediatric Rheumatology, University of California San Francisco, San Francisco, CA, USA.; Department of Genetics, University of Delhi, Delhi, India., Kumar S; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India., Dwivedi VP; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India., Zhao X; Department of Orthopedics Surgery, New York University School of Medicine, New York, NY, USA.; Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT, USA., Panda AK; Product Development Cell, National Institute of Immunology, New Delhi, India., Das HR; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Liu CJ; Department of Orthopedics Surgery, New York University School of Medicine, New York, NY, USA.; Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT, USA.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 21; Vol. 14 (1), pp. 14306. Date of Electronic Publication: 2024 Jun 21.

Adjunct Therapy With All-trans-Retinoic Acid Improves Therapeutic Efficacy Through Immunomodulation While Treating Tuberculosis With Antibiotics in Mice.

Autor: Singh B; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India., Pahuja I; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Yadav P; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India., Shaji A; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Chaturvedi S; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Ranganathan A; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India., Dwivedi VP; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India., Das G; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 May 15; Vol. 229 (5), pp. 1509-1518.

Atosiban and Rutin exhibit anti-mycobacterial activity - An integrated computational and biophysical insight toward drug repurposing strategy against Mycobacterium tuberculosis targeting its essential enzyme HemD.

Autor: Sharma R; Department of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India., Muthu SA; Department of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India., Agarwal M; Department of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India., Mehto NK; Department of Biotechnology, Jamia Hamdard, New Delhi 110062, India., Pahuja I; Department of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India., Grover A; School of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India., Dwivedi VP; Immunobiology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India., Ahmad B; Protein Assembly Lab, Department of Medical Elementology and Toxicology, Jamia Hamdard, New Delhi 110062, India. Electronic address: bashirahmad_sch@jamiahamdard.ac.in., Grover S; Department of Molecular Medicine, Jamia Hamdard, New Delhi 110062, India. Electronic address: sonamgrover@jamiahamdard.ac.in.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 6), pp. 127208. Date of Electronic Publication: 2023 Oct 09.