Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dwight R. Stickney"'
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Obesity-related inflammation-induced insulin resistance and metabolic dysregulation were investigated in retrospective analysis of placebo hematologic and metabolic laboratory data from trials associated with increasing chronic low-grade inflammation
Externí odkaz:
https://doaj.org/article/384f6b4e715a4c42a25b06d968e973f1
Autor:
Jaime Flores-Riveros, Clarence N. Ahlem, Dwight R. Stickney, Daniel A. Destiche, James M. Frincke, William T. Cefalu, Christopher L. Reading
Publikováno v:
Obesity. 21:E343-E349
Objective To study the activity of HE3286 (17α-ethynylandrost-5-ene-3β,7β,17β-triol), an anti-inflammatory sterol that is active in models of obesity-induced inflammation and insulin resistance in high body mass index (BMI) subjects with impaired
Autor:
Fatima S.F. Aerts-Kaya, Dwight R. Stickney, Gerard Wagemaker, James M. Frincke, Shazia Arshad, Trudi P. Visser, Chris L. Reading
Publikováno v:
International Journal of Radiation Oncology Biology Physics, 84(3), E401-E407. Elsevier Inc.
Purpose 5-Androstene-3β,17β-diol (5-AED) stimulates recovery of hematopoiesis after exposure to radiation. To elucidate its cellular targets, the effects of 5-AED alone and in combination with (pegylated) granulocyte colony-stimulating factor and t
Autor:
Michael R. Kennedy, Karen M. Schlangen, Chris Reading, Daniel A. Destiche, Armando Garsd, Barry S Miller, Clarence N. Ahlem, Jessie R. Groothuis, Nanette Onizuka-Handa, Dwight R. Stickney, James M. Frincke
Publikováno v:
Journal of Radiological Protection. 30:687-698
5-androstenediol (5-AED) has been advanced as a possible countermeasure for treating the haematological component of acute radiation syndrome (ARS). It has been used in animal models to stimulate both innate and adaptive immunity and treat infection
Autor:
Dwight R. Stickney, Clarence N. Ahlem, James M. Frincke, David Bell, Evelyn Delorme, Theodore M. Page, Steven K. White, Sonia Villegas, Chris Reading, Michael R. Kennedy
Publikováno v:
Investigational New Drugs. 30:59-78
17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235, Apoptone) is an orally bioavailable synthetic analogue of 3β-androstanediol, that is active in rodent models of prostate and breast cancer, and is in Phase IIa clinical trials for the treatment of
Autor:
Simon Authier, Dwight R. Stickney, Nanette Onizuka-Handa, Christopher L. Reading, Charles Dowding, James M. Frincke, Armando Garsd
Publikováno v:
International Immunopharmacology. 7:500-505
We previously reported that five daily intramuscular doses of 5-androstenediol (AED), a naturally occurring adrenal steroid hormone, stimulated multilineage recovery of bone marrow in rhesus monkeys with radiation-induced myelosuppression after 4.0 G
Autor:
Christopher L, Reading, Dwight R, Stickney, Jaime, Flores-Riveros, Daniel A, Destiche, Clarence N, Ahlem, William T, Cefalu, James M, Frincke
Publikováno v:
Obesity (Silver Spring, Md.). 21(9)
To study the activity of HE3286 (17α-ethynylandrost-5-ene-3β,7β,17β-triol), an anti-inflammatory sterol that is active in models of obesity-induced inflammation and insulin resistance in high body mass index (BMI) subjects with impaired glucose t
Autor:
Clarence N, Ahlem, Michael R, Kennedy, Theodore M, Page, Christopher L, Reading, Steven K, White, John J, McKenzie, Phaedra I, Cole, Dwight R, Stickney, James M, Frincke
Publikováno v:
International journal of clinical and experimental medicine. 4(2)
17α-Ethynyl-androst-5ene-3β, 7β, 17β-triol (HE3286) is an orally bioavailable analogue of androst-5-ene-3β,7β,17β-triol, a non-glucocorticoid anti-inflammatory metabolite of the adrenal steroid, dehydroepiandrosterone. The pharmacology of HE32
Autor:
Dwight R. Stickney, Kenneth A. Foon
Publikováno v:
Current Opinion in Oncology. 4:847-855
Some biologic agents have proven effective in the treatment of lymphoproliferative diseases by stimulating host antitumor immunity or by applying active antitumor properties that specifically or nonspecifically effect tumor growth or tumor survival.