Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dwight R, Pierce"'
Autor:
Dwight R. Pierce, Patricia A. Wight, Neriman T. Kockara, Abdallah Hayar, Pankaj Patyal, Maxim Kozhemyakin, Kim E. Light, Maxim Dobretsov
Publikováno v:
Neuroscience. 398:274-294
The α3 Na+,K+-ATPase (α3NKA) is one of four known α isoforms of the mammalian transporter. A deficiency in α3NKA is linked to severe movement control disorders. Understanding the pathogenesis of these disorders is limited by an incomplete knowled
Autor:
Maxim, Dobretsov, Abdallah, Hayar, Neriman T, Kockara, Maxim, Kozhemyakin, Kim E, Light, Pankaj, Patyal, Dwight R, Pierce, Patricia A, Wight
Publikováno v:
Neuroscience. 398
The α
Publikováno v:
Chemical Senses. 38:685-704
Licking is a repetitive behavior controlled by a central pattern generator. Even though interlick intervals (ILIs) within bursts of licks are considered fairly regular, the conditions that affect their variability are unknown. We analyzed the licking
Publikováno v:
Brain Research. 1378:54-65
Developmental ethanol exposure in rats during postnatal days (PN) 4-6 is known to cause significant loss of the cerebellar Purkinje cells. It is not known what happens to the surviving neurons as they continue to develop. This study was designed to q
Publikováno v:
Neuroscience. 169:1438-1448
Ethanol exposure during postnatal days (PN) 4-6 in rats alters cerebellar development resulting in significant loss of Purkinje cells. There is little knowledge, however, on what happens to the neurons that survive. In this study, rat pups were treat
Publikováno v:
Cerebellum (London, England). 14(4)
Ethanol exposures during the early postnatal period of the rat result in significant death of Purkinje cells (PCs). The magnitude, time-course, and lobular specificity of PC death have been well characterized in several studies. Additionally, signifi
Publikováno v:
Molecular Brain Research. 129:124-134
Previous studies have demonstrated that ethanol exposure during the vulnerable postnatal (PN) day 4–6 period results in a dose-dependent loss of Purkinje neurons in rats by apoptosis. Although the mechanism of ethanol action and the reasons for Pur
Publikováno v:
Toxicology Letters. 150:325-334
A technique is described that allows for the identification and quantification of Purkinje cell loss in cerebellum subsequent to developmental toxic exposures. This technique relies upon the extensively validated findings that the Purkinje cell is th
Publikováno v:
Neuroscience. 114:327-337
The present study was designed to evaluate the time course and manner of Purkinje cell death following a single ethanol dose delivered intragastrically on postnatal day (PN) 4 to rat pups. Analysis included immunolabeling of Purkinje cells with antib
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1650-1659
Background: Ethanol cxposure is a consistent and reliable producer of neuronal toxicity, especially during periods of enhanced neuronal vulnerability. For rat cerebellar Purkinje cells, the postnatal period during the time of the brain growth spurt e