Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dwight Naime"'
Publikováno v:
Journal of Biological Chemistry. 271:17114-17118
Adenosine modulates generation of superoxide anion by neutrophils via occupancy of specific adenosine A2A receptors. However, the intracellular signal transduction pathways by which occupancy of neutrophil adenosine A2A receptors inhibits superoxide
Autor:
Brian D. Golden, M B Whitlow, Richard I. Levin, Rochelle Hirschhorn, Maryann L. Huie, Bruce N. Cronstein, Carlos Lozada, Dwight Naime, Phoebe A. Recht
Publikováno v:
Proceedings of the National Academy of Sciences. 92:8378-8382
To examine the role of complement components as regulators of the expression of endothelial adhesive molecules in response to immune complexes (ICs), we determined whether ICs stimulate both endothelial adhesiveness for leukocytes and expression of E
Publikováno v:
Arthritis & Rheumatism. 38:1040-1045
Objective. The acute antiinflammatory effects of methotrexate are mediated, at least in part, by increased extracellular adenosine concentrations at inflamed sites. This observation suggests that other agents that increase extracellular adenosine con
Publikováno v:
Purine and Pyrimidine Metabolism in Man VIII ISBN: 9781461361053
The introduction of low-dose, intermittent methotrexate was the single most important advance made in the treatment of Rheumatoid Arthritis during the past decade. Although methotrexate was initially introduced for the treatment of RA as a folate ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0e509f03fe6c6ba47d13f87b919a58
https://doi.org/10.1007/978-1-4615-2584-4_89
https://doi.org/10.1007/978-1-4615-2584-4_89
Methotrexate, a folate antagonist, is a potent antiinflammatory agent when used weekly in low concentrations. We examined the hypothesis that the antiphlogistic effects of methotrexate result from its capacity to promote intracellular accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3048c1cce5e80c507e290fe7269d68
https://europepmc.org/articles/PMC288465/
https://europepmc.org/articles/PMC288465/
Publikováno v:
Pflügers Archiv European Journal of Physiology. 431:R225-R226
TSG-6 is an arthritis-associated hyaluronan binding protein whose production in synovial cells, chondrocytes, fibroblasts and mononuclear cells is stimulated by TNF-alpha and IL-1. The purpose of this study was to gain insights into the role of TSG-6