Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Dwight E. Bergles"'
Autor:
Yung-Tian A. Gau, Eric T. Hsu, Richard J. Cha, Rebecca W. Pak, Loren L. Looger, Jin U. Kang, Dwight E. Bergles
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Astrocytes are a direct target of neuromodulators and can influence neuronal activity on broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our knowledge about how astrocytes are recruited during different
Externí odkaz:
https://doaj.org/article/a052047cc38642a6a9b08497e2864520
Publikováno v:
PLoS Biology, Vol 21, Iss 6 (2023)
Intrinsically generated neural activity propagates through the developing auditory system to promote maturation and refinement of sound processing circuits prior to hearing onset. This early patterned activity is induced by non-sensory supporting cel
Externí odkaz:
https://doaj.org/article/0a87af0eed9a44a8b41a4b5591e2e065
Autor:
Honghua Guan, Dawei Li, Hyeon-cheol Park, Ang Li, Yuanlei Yue, Yungtian A. Gau, Ming-Jun Li, Dwight E. Bergles, Hui Lu, Xingde Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The acquisition speed of two-photon fiberscopes is currently suboptimal. Here the authors report advances, including a high-speed scanner and down-sampling scheme as well as a two-stage deep learning (DL) algorithm, to allow high-speed, high-resoluti
Externí odkaz:
https://doaj.org/article/1a13c85762f34398977dc7154eb00f1a
Autor:
Cody L. Call, Dwight E. Bergles
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Myelination patterns of different neurons in grey matter have not been fully defined. Here, the authors show that axon diameter and neuronal identity influence myelination patterns in the intact mouse somatosensory cortex. In vivo imaging revealed th
Externí odkaz:
https://doaj.org/article/c346bd3222c5430cb2eb4580c03d6065
Autor:
Kateryna Murlanova, Yan Jouroukhin, Ksenia Novototskaya-Vlasova, Shovgi Huseynov, Olga Pletnikova, Michael J. Morales, Yun Guan, Atsushi Kamiya, Dwight E. Bergles, David M. Dietz, Mikhail V. Pletnikov
Publikováno v:
Cells, Vol 12, Iss 10, p 1412 (2023)
Astrocytes express mu/µ opioid receptors, but the function of these receptors remains poorly understood. We evaluated the effects of astrocyte-restricted knockout of µ opioid receptors on reward- and aversion-associated behaviors in mice chronicall
Externí odkaz:
https://doaj.org/article/26d7ea31e0aa4d55a6b9ddc5ba3e91bc
Autor:
Liang Ye, Murat Orynbayev, Xiangyu Zhu, Eunice Y. Lim, Ram R. Dereddi, Amit Agarwal, Dwight E. Bergles, Manzoor A. Bhat, Martin Paukert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The effects of norepinephrine on sensory processing in cortical networks are altered by recreational drugs like ethanol. The authors show that ethanol suppresses the activation of astrocytes by inhibiting norepinephrine release which may contribute t
Externí odkaz:
https://doaj.org/article/2c1ad302fc1a4bc19e4ebac3ad4638f3
Autor:
Honghua Guan, Dawei Li, Hyeon-cheol Park, Ang Li, Yuanlei Yue, Yung-Tian A. Gau, Ming-Jun Li, Dwight E. Bergles, Hui Lu, Xingde Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/bf6b157f22b6497b9a8c75b15d2f24cb
GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration
Autor:
Rabia R. Khawaja, Amit Agarwal, Masahiro Fukaya, Hey-Kyeong Jeong, Scott Gross, Estibaliz Gonzalez-Fernandez, Jonathan Soboloff, Dwight E. Bergles, Shin H. Kang
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109147- (2021)
Summary: Oligodendrocyte precursor cells (OPCs) are essential for developmental myelination and oligodendrocyte regeneration after CNS injury. These progenitors express calcium-permeable AMPA receptors (AMPARs) and form direct synapses with neurons t
Externí odkaz:
https://doaj.org/article/c6a1455b301e42c6970b60b10b9ef2bc
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Oligodendrocytes exert a profound influence on neural circuits by accelerating action potential conduction, altering excitability, and providing metabolic support. As oligodendrogenesis continues in the adult brain and is essential for myelin repair,
Externí odkaz:
https://doaj.org/article/f8069b08e3df4088ba9d2aedbb3c3e2e
Autor:
Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108610- (2021)
Summary: Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axon
Externí odkaz:
https://doaj.org/article/3365b3bdc34a429095f1971a8c5318cd