Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dwayne Bisgrove"'
Autor:
Claudia Hetzer, Dwayne Bisgrove, Michael S Cohen, Angelika Pedal, Katrin Kaehlcke, Anja Speyerer, Kerstin Bartscherer, Jack Taunton, Melanie Ott
Publikováno v:
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
The transcriptional activity of the integrated HIV provirus is dependent on the chromatin organization of the viral promoter and the transactivator Tat. Tat recruits the cellular pTEFb complex and interacts with several chromatin-modifying enzymes, i
Externí odkaz:
https://doaj.org/article/9d4ea5c3d3af4027bd7a869b69cb54b6
Publikováno v:
Expert Review of Anti-infective Therapy. 3:805-814
While great strides have been made in the treatment of HIV infection with highly active antiretroviral therapy, an actual cure remains out of grasp. One confounding factor is the persistence of a small population of infected cells containing transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d030cb78f2d1a6b90398816ad7aa50
https://doi.org/10.1586/14787210.3.5.805
https://doi.org/10.1586/14787210.3.5.805
Autor:
Qiang Zhang, Lily Mak, Joann Lau, Sungyoo Cho, Dwayne Bisgrove, Lei Zeng, Eric Verdin, Melanie Ott, Katrin Kaehlcke, Martina Schnölzer, Sebastian Schröder, Ming-Ming Zhou
Publikováno v:
The Journal of biological chemistry. 287(2)
The positive transcription elongation factor b (P-TEFb) exists in two forms in cells as follows: an inactive form where the core components cyclin T1 and CDK9 are incorporated in the 7SK small nuclear ribonucleoprotein complex containing the inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e39396524cb3a5d4c18ad68ed4c2ab
https://pubmed.ncbi.nlm.nih.gov/22084242
https://pubmed.ncbi.nlm.nih.gov/22084242
We have identified a conserved region in the C-terminal domain of bromodomain-containing protein 4 (BRD4) that mediates its specific interaction with positive transcription elongation factor b (P-TEFb). This domain is highly conserved in testis-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997bb6843b346ac3e374219fb1847fea
https://europepmc.org/articles/PMC1959443/
https://europepmc.org/articles/PMC1959443/
Autor:
Dwayne Bisgrove, Angelika Pedal, Claudia Hetzer, Katrin Kaehlcke, Michael S. Cohen, Melanie Ott, Anja Speyerer, Kerstin Bartscherer, Jack Taunton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
PLoS ONE, Vol 2, Iss 1, p e151 (2007)
The transcriptional activity of the integrated HIV provirus is dependent on the chromatin organization of the viral promoter and the transactivator Tat. Tat recruits the cellular pTEFb complex and interacts with several chromatin-modifying enzymes, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413cfe5b6967b8d9bd1ed2eefe3bd38f
http://europepmc.org/articles/PMC1764712
http://europepmc.org/articles/PMC1764712
Autor:
Dwayne Bisgrove, Charles C. Berry, Sridhar Hannenhalli, Mary K. Lewinski, Christian Hoffmann, Joseph R. Ecker, Eric Verdin, Hongwu Chen, Paul Shinn, Frederic D. Bushman
Publikováno v:
Journal of virology. 79(11)
We have investigated regulatory sequences in noncoding human DNA that are associated with repression of an integrated human immunodeficiency virus type 1 (HIV-1) promoter. HIV-1 integration results in the formation of precise and homogeneous junction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accc0c7e6ab2d780bd1b0f9505f2f885
https://pubmed.ncbi.nlm.nih.gov/15890899
https://pubmed.ncbi.nlm.nih.gov/15890899
Autor:
Dwayne Bisgrove, Warner C. Greene, Hakju Kwon, David Fenard, Lin Feng Chen, Samuel A. Williams, Eric Verdin
Publikováno v:
The Journal of biological chemistry. 279(40)
A subset of quiescent memory CD4 T cells harboring integrated but transcriptionally silent proviruses poses a currently insurmountable barrier to the eradication of the human immunodeficiency virus (HIV) in infected patients. Induction of HIV gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e21a06a8824731025de1377d0e8b7d8
https://pubmed.ncbi.nlm.nih.gov/15284245
https://pubmed.ncbi.nlm.nih.gov/15284245