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of 16
pro vyhledávání: '"Dwaine Simon Burley"'
Publikováno v:
Cardiovascular Endocrinology. 3:19-26
Autor:
Péter Ferdinandy, Judit Pipis, Zoltán Giricz, Anikó Görbe, Gary F. Baxter, Dwaine Simon Burley
Publikováno v:
British Journal of Pharmacology. 158:1495-1502
Background and purpose: Hyperlipidaemia interferes with cardioprotective mechanisms, but the cause of this phenomenon is largely unknown, although hyperlipidaemia impairs the cardioprotective NO–cGMP system. However, it is not known if natriuretic
Publikováno v:
British Journal of Pharmacology. 152:855-869
It is clear that multiple signalling pathways regulate the critical balance between cell death and survival in myocardial ischaemia–reperfusion. Recent attention has focused on the activation of survival or salvage kinases, particularly during repe
Limiting the injurious effects of myocardial ischemia-reperfusion is a desirable therapeutic target, which has been investigated extensively over the last three decades. Here we provide an up to date review of the literature documenting the experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a5a26fcffd6ab50ab106a613a9f666
Publikováno v:
Basic Research in Cardiology
B-type natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), and (Cys-18)-atrial natriuretic factor (4–23) amide (C-ANF), are cytoprotective under conditions of ischemia–reperfusion, limiting infarct size. ATP-sensitive K+ channel (KATP
Autor:
Gary F. Baxter, Dwaine Simon Burley
Publikováno v:
British Journal of Pharmacology. 153:1-3
The last five years have witnessed a remarkable resurgence of interest in myocardial reperfusion injury. Reperfusion is absolutely essential to salvage ischaemic myocardium but experimental and clinical studies show that reperfusion-associated injury
Autor:
Anikó Görbe, Péter Ferdinandy, Tamás Csont, Andrea Szunyog, Gary F. Baxter, Dwaine Simon Burley, Zoltán Giricz
Publikováno v:
Basic research in cardiology. 105(5)
Nitric oxide (NO) and B-type natriuretic peptide (BNP) are protective against ischemia-reperfusion injury as they increase intracellular cGMP level via activation of soluble (sGC) or particulate guanylate cyclases (pGC), respectively. The aim of the
Autor:
Gary F. Baxter, Dwaine Simon Burley
Publikováno v:
Current opinion in pharmacology. 9(2)
Postconditioning is an intervention in which controlled, brief, intermittent periods of ischaemia at the onset of reperfusion protect myocardium from the lethal consequences of reperfusion ('reperfusion injury'). Postconditioning has been demonstrate
Publikováno v:
Heart failure reviews. 12(3-4)
The myocardium represents a major source of several families of peptide hormones under normal physiological conditions and the plasma concentrations of many of these "cardiac peptides" (or related pro-peptide fragments) are substantially augmented in
Autor:
Dwaine Simon Burley, Gary F. Baxter
Publikováno v:
Basic research in cardiology. 102(6)
Natriuretic peptides are regulatory autacoids in the mammalian myocardium whose functions, mediated via particulate guanylyl cyclase/cGMP, may include cytoprotection against ischaemia-reperfusion injury. Previous work has identified that B-type natri