Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Dwaine Banton"'
5
Reduced scale model qualification of 5‐L and 250‐ml bioreactors using multivariant visualization and Bayesian inferential methods
Autor: Dwaine Banton, Christopher Thomas Canova, Eugene Schaefer, Sara Naguib, Kevin Clark
Publikováno v: Biotechnology and Bioengineering. 117:1337-1347
A novel method for the qualification of reduced scale models (RSMs) was illustrated using data from both a 250-ml advanced microscale bioreactor (ambr) and a 5-L bioreactor RSM for a 2,000-L manufacturing scale process using a CHO cell line to produc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4e82ac469b238b29868d39ec34e41d
https://doi.org/10.1002/bit.27282
Zobrazit plný text záznamu
6
The Use of Bayesian Hierarchical Logistic Regression in the Development of a Modular Viral Inactivation Claim
Autor: Dominick A. Vacante, Josh Goldstein, Dwaine Banton, John Schreffler, Ben Bulthuis, Michael Wineburg
Publikováno v: PDA Journal of Pharmaceutical Science and Technology. 73:552-561
Low pH inactivation of enveloped viruses has historically been shown to be an effective viral inactivation step in biopharmaceutical manufacturing. To date, most statistical analyses supporting modular low pH viral inactivation claims have used descr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a86744decd87de0aadf088bef309c1
https://doi.org/10.5731/pdajpst.2019.010116
Zobrazit plný text záznamu
7
Residue-Specific Impact of EDTA and Methionine on Protein Oxidation in Biotherapeutics Formulations Using an Integrated Biotherapeutics Drug Product Development Workflow
Autor: Santosh V. Thakkar, Danika Rodrigues, Bo Zhai, Dwaine Banton, Sandeep Somani, Alex Javidi, Andrew Mahan, Stuart Ember, Dominick DeGrazio, Subinay Ganguly, Ketan Amin, Hirsh Nanda
Publikováno v: Journal of pharmaceutical sciences.
The rational design and selection of formulation composition to meet molecule-specific and product-specific needs are critical for biotherapeutics development to ensure physical and chemical stability. This work, based on three antibody-based (mAb) p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82868a3378cdaad24636527f8bb1c1cf
https://pubmed.ncbi.nlm.nih.gov/36130676
Zobrazit plný text záznamu
8
The current state of Bayesian methods in nonclinical pharmaceutical statistics: Survey results and recommendations from the DIA/ASA-BIOP Nonclinical Bayesian Working Group
Autor: Steven Novick, James D. Stamey, Paul Faya, Dwaine Banton, John W. Seaman, Perceval Sondag, Bruno Boulanger
Publikováno v: Pharmaceutical statisticsREFERENCES. 20(2)
The use of Bayesian methods to support pharmaceutical product development has grown in recent years. In clinical statistics, the drive to provide faster access for patients to medical treatments has led to a heightened focus by industry and regulator
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538a5878ed5e758319cc5201905473bb
https://pubmed.ncbi.nlm.nih.gov/33025743
Zobrazit plný text záznamu
9
Connecting Our Gut Feeling and How Our Gut Feels: The Role of Well-being Attributes in Irritable Bowel Syndrome
Autor: Ashkan Farhadi, Laurie Keefer, Dwaine Banton
Publikováno v: Journal of Neurogastroenterology and Motility
Background/Aims There is a close relationship between the mind and gut in the pathogenesis of functional bowel disorders. Common psychological disturbances such as depression and anxiety are not uncommon in those with irritable bowel syndrome (IBS).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d77aa83172ed10c10783ff59b13dbf
https://pubmed.ncbi.nlm.nih.gov/29605984
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje