Inhibition of demethylases by GSK-J1/J4.

Autor: Heinemann B; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Nielsen JM; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Hudlebusch HR; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Lees MJ; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark., Larsen DV; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Boesen T; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Labelle M; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Gerlach LO; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Birk P; EpiTherapeutics Aps, Ole Maaløes Vej 3, 2200 Copenhagen, Denmark., Helin K; 1] Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark [2] Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark [3] The Danish Stem Cell Center (DanStem), University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark.

Publikováno v: Nature [Nature] 2014 Oct 02; Vol. 514 (7520), pp. E1-2.

Investigation of two novel biochemical markers of inflammation, matrix metalloproteinase and cathepsin generated fragments of C-reactive protein, in patients with ankylosing spondylitis.

Autor: Skjøt-Arkil H; Nordic Bioscience A/S, Herlev, Denmark. hbe@nordicbioscience.com, Schett G, Zhang C, Larsen DV, Wang Y, Zheng Q, Larsen MR, Nawrocki A, Bay-Jensen AC, Henriksen K, Christiansen C, Alexandersen P, Leeming DJ, Karsdal MA

Publikováno v: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2012 May-Jun; Vol. 30 (3), pp. 371-9. Date of Electronic Publication: 2012 Jun 26.

Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis.

Autor: Vassiliadis E; Nordic Bioscience A/S, Herlev, Denmark. eva@nordicbioscience.com, Veidal SS, Simonsen H, Larsen DV, Vainer B, Chen X, Zheng Q, Karsdal MA, Leeming DJ

Publikováno v: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2011 Aug; Vol. 16 (5), pp. 426-33. Date of Electronic Publication: 2011 May 25.

Measurement of CO3-610, a potential liver biomarker derived from matrix metalloproteinase-9 degradation of collagen type iii, in a rat model of reversible carbon-tetrachloride-induced fibrosis.

Autor: Vassiliadis E; Nordic Bioscience, Herlev, Denmark., Larsen DV, Clausen RE, Veidal SS, Barascuk N, Larsen L, Simonsen H, Silvestre TS, Hansen C, Overgaard T, Leeming DJ, Karsdal MA

Publikováno v: Biomarker insights [Biomark Insights] 2011 Mar 24; Vol. 6, pp. 49-58. Date of Electronic Publication: 2011 Mar 24.

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen.

Autor: Barascuk N; Nordic Bioscience A/S, Herlev, Denmark. nb@nordicbioscience.com, Veidal SS, Larsen L, Larsen DV, Larsen MR, Wang J, Zheng Q, Xing R, Cao Y, Rasmussen LM, Karsdal MA

Publikováno v: Clinical biochemistry [Clin Biochem] 2010 Jul; Vol. 43 (10-11), pp. 899-904. Date of Electronic Publication: 2010 Apr 07.