What are the DNA lesions underlying formaldehyde toxicity?

Autor: Benedict, Bente, Kristensen, Stella Munkholm, Duxin, Julien P.

Publikováno v: In DNA Repair June 2024 138

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Catalytic and noncatalytic functions of DNA polymerase κ in translesion DNA synthesis

Autor: Sellés-Baiget, Selene, Ambjørn, Sara M., Carli, Alberto, Hendriks, Ivo A., Gallina, Irene, Davey, Norman E., Benedict, Bente, Zarantonello, Alessandra, Gadi, Sampath A., Meeusen, Bob, Hertz, Emil P. T., Slappendel, Laura, Semlow, Daniel, Sturla, Shana, Nielsen, Michael L., Nilsson, Jakob, Miller, Thomas C. R., Duxin, Julien P.

Publikováno v: Nature Structural and Molecular Biology; 20240101, Issue: Preprints p1-15, 15p

Targeting DNA-Protein Crosslinks via Post-Translational Modifications

Autor: Leng, Xueyuan, Duxin, Julien P.

Publikováno v: Leng, X & Duxin, J P 2022, ' Targeting DNA-Protein Crosslinks via Post-Translational Modifications ', Frontiers in Molecular Biosciences, vol. 9, 944775 . https://doi.org/10.3389/fmolb.2022.944775

Covalent binding of proteins to DNA forms DNA-protein crosslinks (DPCs), which represent cytotoxic DNA lesions that interfere with essential processes such as DNA replication and transcription. Cells possess different enzymatic activities to countera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd96499d67e7a809a1cf3de87943980
https://doi.org/10.3389/fmolb.2022.944775