Characterization of [ ¹¹ C]PXT012253 as a PET Radioligand for mGlu 4 Allosteric Modulators in Nonhuman Primates.

Autor: Takano A; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Nag S; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Jia Z; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Jahan M; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Forsberg A; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Arakawa R; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Grybäck P; Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Solna, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden., Duvey G; Prexton Therapeutics, 14 Chemin des Aulx, 1228, Plan-les-Ouates, Geneva, Switzerland., Halldin C; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden. Christer.Halldin@ki.se., Charvin D; Prexton Therapeutics, 14 Chemin des Aulx, 1228, Plan-les-Ouates, Geneva, Switzerland. Delphine.Charvin@prextontherapeutics.com.

Publikováno v: Molecular imaging and biology [Mol Imaging Biol] 2019 Jun; Vol. 21 (3), pp. 500-508.

An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates.

Autor: Charvin D; Prexton Therapeutics SA, 1228 Plan-les-Ouates, Geneva, Switzerland., Di Paolo T; Neuroscience Research Unit CHU de Québec, CHUL Pavillon and Faculty of Pharmacy, Laval University, Quebec City, Quebec, Canada., Bezard E; Motac Neuroscience Ltd, Manchester, United Kingdom., Gregoire L; Neuroscience Research Unit CHU de Québec, CHUL Pavillon and Faculty of Pharmacy, Laval University, Quebec City, Quebec, Canada., Takano A; Karolinska Institutet, Centre for Psychiatry Research, Department of Clinical Neuroscience, Stockholm, Sweden., Duvey G; Prexton Therapeutics SA, 1228 Plan-les-Ouates, Geneva, Switzerland., Pioli E; Motac Neuroscience Ltd, Manchester, United Kingdom., Halldin C; Karolinska Institutet, Centre for Psychiatry Research, Department of Clinical Neuroscience, Stockholm, Sweden., Medori R; Prexton Therapeutics SA, 1228 Plan-les-Ouates, Geneva, Switzerland., Conquet F; Prexton Therapeutics SA, 1228 Plan-les-Ouates, Geneva, Switzerland.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2018 Oct; Vol. 33 (10), pp. 1619-1631. Date of Electronic Publication: 2018 Sep 14.

Correlation of SNR Value on DPOAE Examination with HSP70 Levels in Blood and HSP70 Expression in Cochlea of Noise Model Rattus norvegicus as an Indicator of Inner Ear Damage.

Autor: Pratiwi, Florensia Elita¹, Haryuna, Tengku Siti Hajar¹ tengkusitihajarharyuna@usu.ac.id, Adriztina, Indri¹, Khalid, Khalisanni²

Publikováno v: Advancements in Life Sciences. May2024, Vol. 11 Issue 2, p322-328. 7p.

Ortho-directed metallation of π-deficient heterocycles in connection with palladium-catalyzed biaryl cross-coupling — Synthesis of marine alkaloids of the pyridoacridine series.

Autor: Godard, A, Rocca, P, Guillier, F, Duvey, G, Nivoliers, F, Marsais, F, Quéguiner, G

Publikováno v: Canadian Journal of Chemistry; Nov2001, Vol. 79 Issue 11, p1754-1761, 8p

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