Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

Autor: Fernández-Castañeda, Anthony, Lu, Peiwen, Geraghty, Anna C., Song, Eric, Lee, Myoung-Hwa, Wood, Jamie, O’Dea, Michael R., Dutton, Selena, Shamardani, Kiarash, Nwangwu, Kamsi, Mancusi, Rebecca, Yalçın, Belgin, Taylor, Kathryn R., Acosta-Alvarez, Lehi, Malacon, Karen, Keough, Michael B., Ni, Lijun, Woo, Pamelyn J., Contreras-Esquivel, Daniel, Toland, Angus Martin Shaw, Gehlhausen, Jeff R., Klein, Jon, Takahashi, Takehiro, Silva, Julio, Israelow, Benjamin, Lucas, Carolina, Mao, Tianyang, Peña-Hernández, Mario A., Tabachnikova, Alexandra, Homer, Robert J., Tabacof, Laura, Tosto-Mancuso, Jenna, Breyman, Erica, Kontorovich, Amy, McCarthy, Dayna, Quezado, Martha, Vogel, Hannes, Hefti, Marco M., Perl, Daniel P., Liddelow, Shane, Folkerth, Rebecca, Putrino, David, Nath, Avindra, Iwasaki, Akiko, Monje, Michelle

Publikováno v: In Cell 7 July 2022 185(14):2452-2468

Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain.

Autor: Fernández-Castañeda A; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Lu P; Department of Immunobiology, Yale University, New Haven CT USA., Geraghty AC; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Song E; Department of Immunobiology, Yale University, New Haven CT USA., Lee MH; National Institute of Neurological Disorders and Stroke, Besthesda MD USA., Wood J; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Yalçın B; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Taylor KR; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Dutton S; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Acosta-Alvarez L; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Ni L; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Contreras-Esquivel D; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA., Gehlhausen JR; Department of Immunobiology, Yale University, New Haven CT USA., Klein J; Department of Immunobiology, Yale University, New Haven CT USA., Lucas C; Department of Immunobiology, Yale University, New Haven CT USA., Mao T; Department of Immunobiology, Yale University, New Haven CT USA., Silva J; Department of Immunobiology, Yale University, New Haven CT USA., Peña-Hernández MA; Department of Immunobiology, Yale University, New Haven CT USA., Tabachnikova A; Department of Immunobiology, Yale University, New Haven CT USA., Takahashi T; Department of Immunobiology, Yale University, New Haven CT USA., Tabacof L; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Tosto-Mancuso J; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Breyman E; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Kontorovich A; Cardiovascular Research Institute, Mount Sinai School of Medicine, New York, NY USA., McCarthy D; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Quezado M; National Cancer Institute, Besthesda MD USA., Hefti M; Department of Pathology, University of Iowa, Iowa City, IA USA., Perl D; Department of Pathology, Uniformed Services University of Health Sciences, Bethesda MD USA., Folkerth R; Office of Chief Medical Examiner, New York, NY USA., Putrino D; Abilities Research Center, Department of Rehabilitation and Human Performance, Mount Sinai School of Medicine, New York, NY USA., Nath A; National Institute of Neurological Disorders and Stroke, Besthesda MD USA., Iwasaki A; Department of Immunobiology, Yale University, New Haven CT USA.; Howard Hughes Medical Institute, Yale University, New Haven CT USA., Monje M; Department of Neurology and Neurological Sciences, Stanford University, Stanford CA USA.; Howard Hughes Medical Institute, Stanford University, Stanford CA USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2022 Jan 10. Date of Electronic Publication: 2022 Jan 10.