Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS.

Autor: Dutra Silva J; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Su Y; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Calfee CS; Dept of Medicine, Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA.; Dept of Anesthesia, University of California, San Francisco, San Francisco, CA, USA.; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Delucchi KL; Dept of Psychiatry, University of California, San Francisco, San Francisco, CA, USA., Weiss D; Dept of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, UK., O'Kane C; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Krasnodembskaya AD; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, UK a.krasnodembskaya@qub.ac.uk.

Publikováno v: The European respiratory journal [Eur Respir J] 2021 Jul 01; Vol. 58 (1). Date of Electronic Publication: 2021 Jul 01 (Print Publication: 2021).