Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dustin Singer"'
Autor:
Chang-Hyeock Byeon, Judith G. Levin, In-Ja L. Byeon, Tiyun Wu, Angela M. Gronenborn, Mithun Mitra, Dustin Singer
Publikováno v:
Biochemistry, vol 55, iss 21
Human APOBEC3B (A3B) is a member of the APOBEC3 (A3) family of cytidine deaminases, which function as DNA mutators and restrict viral pathogens and endogenous retrotransposons. Recently, A3B was identified as a major source of genetic heterogeneity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54dc5131d595963cc4fcfb41b8834f2
https://doi.org/10.1021/acs.biochem.6b00382
https://doi.org/10.1021/acs.biochem.6b00382
Autor:
Dustin Singer, Raphael N. Vuille-dit-Bille, Luca Mariotta, François Verrey, Simone M. R. Camargo, Tamara Ramadan
Near complete reabsorption of filtered amino acids is a main specialized transport function of the kidney proximal tubule. This evolutionary conserved task is carried out by a subset of luminal and basolateral transporters that together form the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffbd3f720a8586328b1292472b26bb5
http://doc.rero.ch/record/320432/files/424_2009_Article_638.pdf
http://doc.rero.ch/record/320432/files/424_2009_Article_638.pdf
Autor:
Dustin Singer, Charles E. Johnston
Publikováno v:
JBJS Open Access. 4:e0004
Background This study assessed the outcomes, at skeletal maturity, for 34 patients in whom congenital pseudarthrosis of the tibia (CPT) had been treated with intramedullary (IM) rod fixation. Methods The results in skeletally mature patients in whom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8953fdc3ea9488a5329c0bc4f5472474
https://doi.org/10.2106/jbjs.oa.19.00004
https://doi.org/10.2106/jbjs.oa.19.00004
Autor:
Kathryn Hinchee-Rodriguez, Kamil Hercík, Judith G. Levin, Chang-Hyeock Byeon, Lisa M. Charlton, Gabriel Nam, Angela M. Gronenborn, Mithun Mitra, Gisela Heidecker, In-Ja L. Byeon, Jinwoo Ahn, Dustin Singer, Shawn Hill
Publikováno v:
Nucleic Acids Research
Human APOBEC3A (A3A) is a single-domain cytidine deaminase that converts deoxycytidine residues to deoxyuridine in single-stranded DNA (ssDNA). It inhibits a wide range of viruses and endogenous retroelements such as LINE-1, but it can also edit geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf9a9eb1a57d0f0a8d0454248d69c8d
https://doi.org/10.1093/nar/gkt945
https://doi.org/10.1093/nar/gkt945
Autor:
Brigitte Herzog, Simone M. R. Camargo, Dustin Singer, Tamara Ramadan, François Verrey, Manuel Palacín, Claudia Stoeger, Tony Lahoutte, Adriano Guetg, Luca Mariotta
Publikováno v:
The Journal of Physiology. 590:6413-6424
The uniporter TAT1 (Slc16a10) mediates the facilitated diffusion of aromatic amino acids (AAAs) across basolateral membranes of kidney, small intestine and liver epithelial cells, and across the plasma membrane of non-epithelial cells like skeletal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339866030c795d1df8b06071d13bc4ad
https://doi.org/10.1113/jphysiol.2012.239574
https://doi.org/10.1113/jphysiol.2012.239574
Autor:
Renu Sarao, Dustin Singer, Christine Remy, J. Andrew Pospisilik, François Verrey, Victoria Makrides, Simone M. R. Camargo, Gerti Stange, Ursula Danilczyk, Andreas Richter, Sudha Arya, Chahira Benabbas, Carsten A. Wagner, Tamara Ramadan, Josef M. Penninger
Publikováno v:
Nature. 444:1088-1091
Angiotensin -converting enzyme 2 (ACE2) is a regulator of the renin angiotensin system involved in acute lung failure, cardiovascular functions and severe acute respiratory syndrome (SARS) infections in mammals. A gene encoding a homologue to ACE2, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c146aba0f6ebc3faad8bb9162ca9e3
https://doi.org/10.1038/nature05475
https://doi.org/10.1038/nature05475
Autor:
Katja Huggel, Oliver Götze, Raphael N. Vuille-dit-Bille, Dustin Singer, François Verrey, Luca Mariotta, Simone M. R. Camargo, Tamara Ramadan
Publikováno v:
J. Pharmacol. Exp. Ther.
Levodopa (L-DOPA) is the naturally occurring precursor amino acid for dopamine and the main therapeutic agent for neurologic disorders due to dopamine depletion, such as Parkinson's disease. l-DOPA absorption in small intestine has been suggested to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cbb723c98c75299051e352e551d03c
https://pubmed.ncbi.nlm.nih.gov/25073474
https://pubmed.ncbi.nlm.nih.gov/25073474
Autor:
Brigitte Herzog, David P. Wolfer, Matthias Schäfer, Tamara Ramadan, Sabine Werner, Josef M. Penninger, Luca Mariotta, Simone M. R. Camargo, Dustin Singer, François Verrey, Katja Huggel
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 303(6)
Mutations in the main intestinal and kidney luminal neutral amino acid transporter B0AT1 (Slc6a19) lead to Hartnup disorder, a condition that is characterized by neutral aminoaciduria and in some cases pellagra-like symptoms. These latter symptoms ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a731b377f19528327ae36604ca9686
https://pubmed.ncbi.nlm.nih.gov/22790597
https://pubmed.ncbi.nlm.nih.gov/22790597
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3be914e957b1222c5bb3ebb821735f8
https://doi.org/10.1096/fasebj.25.1_supplement.1038.19
https://doi.org/10.1096/fasebj.25.1_supplement.1038.19
Autor:
Simone M. R. Camargo, Dustin Singer
Publikováno v:
Channels
Channels, Taylor & Francis, 2011, 5 (5), pp.408-421. ⟨10.4161/chan.5.5.16470⟩
Channels, Taylor & Francis, 2011, 5 (5), pp.408-421. ⟨10.4161/chan.5.5.16470⟩
Neutral amino acid transporters of the SLC6 family are expressed at the apical membrane of kidney and/or small intestine, where they (re-)absorb amino acids into the body. In this review we present the results concerning the dependence of their apica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1735b3b9674caae221f2f982a43d2b4
https://hal.archives-ouvertes.fr/hal-01004572
https://hal.archives-ouvertes.fr/hal-01004572