Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Dustin R. Masser"'
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background Alterations to cellular and molecular programs with brain aging result in cognitive impairment and susceptibility to neurodegenerative disease. Changes in DNA methylation patterns, an epigenetic modification required for various C
Externí odkaz:
https://doaj.org/article/63e1a0afff5b4799ad0eb10f2eaeecc0
Autor:
Sreemathi Logan, Gavin A. Pharaoh, M. Caleb Marlin, Dustin R. Masser, Satoshi Matsuzaki, Benjamin Wronowski, Alexander Yeganeh, Eileen E. Parks, Pavithra Premkumar, Julie A. Farley, Daniel B. Owen, Kenneth M. Humphries, Michael Kinter, Willard M. Freeman, Luke I. Szweda, Holly Van Remmen, William E. Sonntag
Publikováno v:
Molecular Metabolism, Vol 9, Iss , Pp 141-155 (2018)
Objective: A decline in mitochondrial function and biogenesis as well as increased reactive oxygen species (ROS) are important determinants of aging. With advancing age, there is a concomitant reduction in circulating levels of insulin-like growth fa
Externí odkaz:
https://doaj.org/article/32814f5809cb49c2965d978f0cb0172f
Autor:
Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the diffe
Externí odkaz:
https://doaj.org/article/8ff50482fdfc4d15be815b02c6ed9c50
Autor:
Arlan Richardson, Dustin R. Masser, Laura Otalora, Willard M. Freeman, Archana Unnikrishnan, Niran Hadad, Jordan Jackson, David R. Stanford
Publikováno v:
Neurobiology of Aging. 67:53-66
Brain aging is marked by cognitive decline and increased susceptibility to neurodegeneration. Epigenetic mechanisms, including DNA methylation, are vital to CNS cellular function and memory formation, and are dysregulated with aging and age-related n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659548d837f035bb421d1118bab0847b
https://doi.org/10.1016/j.neurobiolaging.2018.03.009
https://doi.org/10.1016/j.neurobiolaging.2018.03.009
Autor:
Holly Van Remmen, Alexander Yeganeh, Luke I. Szweda, Gavin Pharaoh, Daniel Owen, Satoshi Matsuzaki, Pavithra Premkumar, Eileen E. Parks, Michael Kinter, Benjamin Wronowski, Kenneth M. Humphries, M. Caleb Marlin, Sreemathi Logan, Willard M. Freeman, William E. Sonntag, Dustin R. Masser, Julie A. Farley
Publikováno v:
Molecular Metabolism, Vol 9, Iss, Pp 141-155 (2018)
Molecular Metabolism
Molecular Metabolism
Objective A decline in mitochondrial function and biogenesis as well as increased reactive oxygen species (ROS) are important determinants of aging. With advancing age, there is a concomitant reduction in circulating levels of insulin-like growth fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912334f1bf334db5a5a4db4e3f1b2ed3
https://doi.org/10.1016/j.molmet.2018.01.013
https://doi.org/10.1016/j.molmet.2018.01.013
Autor:
Niran Hadad, Dustin R. Masser, Jordan Jackson, Arlan Richardson, Willard M. Freeman, Archana Unnikrishnan
Publikováno v:
Annals of the New York Academy of Sciences. 1418:69-79
The genomic hypomethylation hypothesis of aging proposes that an overall decrease in global DNA methylation occurs with age, and it has been argued that the decrease in global DNA methylation could be an important factor in aging, resulting in the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e818f6e050ec3d7328ba90f8600f55f2
https://doi.org/10.1111/nyas.13533
https://doi.org/10.1111/nyas.13533
Autor:
David R. Stanford, Willard M. Freeman, Dustin R. Masser, Archana Unnikrishnan, Hunter Porter, Niran Hadad, Michael B. Stout
Publikováno v:
GeroScience. 40:11-29
As geroscience research extends into the role of epigenetics in aging and age-related disease, researchers are being confronted with unfamiliar molecular techniques and data analysis methods that can be difficult to integrate into their work. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f6bbf775c48dca7802009835a49327
https://doi.org/10.1007/s11357-018-0005-3
https://doi.org/10.1007/s11357-018-0005-3
Autor:
Michael H. Elliott, Dustin R. Masser, Michael Kinter, Willard M. Freeman, Laura Otalora, Nicholas W. Clark
Publikováno v:
Journal of Neurochemistry. 143:595-608
Diabetic retinopathy is a neurovascular diabetes complication resulting in vision loss. A wealth of literature reports retinal molecular changes indicative of neural deficits, inflammation, and vascular leakage with chronic diabetes, but the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efb177c25f47daa1756042320a2a55f
https://doi.org/10.1111/jnc.14216
https://doi.org/10.1111/jnc.14216
Alterations to cellular and molecular programs with brain aging result in cognitive impairment and susceptibility to neurodegenerative disease. Changes in DNA methylation patterns, an epigenetic modification required for various CNS functions, are ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f924369f350301393c3ddf8f271b84
Autor:
Dustin R. Masser, Matthew M. Ford, Aditya Pisupati, David R. Stanford, Cory B. Giles, William E. Sonntag, Colleen A. Mangold, Georgina V. Bixler, Jonathan D. Wren, Willard M. Freeman
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 72:16-29
The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbff1968cddf5942af1a6508d22caf5
https://doi.org/10.1093/gerona/glv232
https://doi.org/10.1093/gerona/glv232