Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dustin L. Updike"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Spaulding et al. survey RG/RGG repeats in C. elegans and identify the homologs of Nucleolin (NUCL-1) and GAR1 (GARR-1). RG/RGG repeats are dispensable for nucleolar accumulation but critical for sub-nucleolar phase separation.
Externí odkaz:
https://doaj.org/article/cff468e30834402d8ec734e1de85abdf
Autor:
Jesse D. Rochester, Paige C. Tanner, Catherine S. Sharp, Karolina M. Andralojc, Dustin L. Updike
Publikováno v:
Biology Open, Vol 6, Iss 9, Pp 1355-1363 (2017)
In Caenorhabditis elegans, five pharyngeal gland cells reside in the terminal bulb of the pharynx and extend anterior processes to five contact points in the pharyngeal lumen. Pharyngeal gland cells secrete mucin-like proteins thought to facilitate d
Externí odkaz:
https://doaj.org/article/89eec78a7da5466db0dbd5bcb703a6c8
Autor:
Elisabeth A Marnik, Miguel V Almeida, P Giselle Cipriani, George Chung, Edoardo Caspani, Emil Karaulanov, Hin Hark Gan, John Zinno, Ida J Isolehto, Fridolin Kielisch, Falk Butter, Catherine S Sharp, Roisin M Flanagan, Frederic X Bonnet, Fabio Piano, René F Ketting, Kristin C Gunsalus, Dustin L Updike
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010245 (2022)
LOTUS and Tudor domain containing proteins have critical roles in the germline. Proteins that contain these domains, such as Tejas/Tapas in Drosophila, help localize the Vasa helicase to the germ granules and facilitate piRNA-mediated transposon sile
Externí odkaz:
https://doaj.org/article/71709158c8ad428c89af9008c7d82035
Autor:
Jesse D. Rochester, Hyemin Min, Gita A. Gajjar, Catherine S. Sharp, Nathaniel J. Maki, Jarod A. Rollins, Brett D. Keiper, Joel H. Graber, Dustin L. Updike
Publikováno v:
Dev Biol
Germ granules harbor processes that maintain germline integrity and germline stem cell capacity. Depleting core germ granule components in C. elegans leads to the reprogramming of germ cells, causing them to express markers of somatic differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0843dbe3a41467795fe337df1e8c9d7b
https://doi.org/10.1016/j.ydbio.2022.10.003
https://doi.org/10.1016/j.ydbio.2022.10.003
Autor:
Karolina M Andralojc, Anne C Campbell, Ashley L Kelly, Markus Terrey, Paige C Tanner, Ian M Gans, Michael J Senter-Zapata, Eraj S Khokhar, Dustin L Updike
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule
Externí odkaz:
https://doaj.org/article/d5e11391c9da41e6ad9ae9793657bf23
Autor:
Carolyn M Phillips, Dustin L Updike
Publikováno v:
Genetics
The transparency of Caenorhabditis elegans provides a unique window to observe and study the function of germ granules. Germ granules are specialized ribonucleoprotein (RNP) assemblies specific to the germline cytoplasm, and they are largely conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3589e98b997bb7eeb0d41f7c3ce1f4a1
https://doi.org/10.1093/genetics/iyab195
https://doi.org/10.1093/genetics/iyab195
Autor:
Taiowa A. Montgomery, Joshua M. Svendsen, Erin Osborne Nishimura, Dustin L. Updike, Tarah Vijayasarathy, Taylor N Marks, Kailee J. Reed, Brooke E Montgomery, Dylan M. Parker, Kristen C. Brown
Publikováno v:
Nucleic Acids Research
Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of small RNAs required for proper germline development. To identify the roles of piRNAs and siRNAs in regulating gene expression in Caenorhabditis elegans, we sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5712bff01c41c551caa991553294a33f
https://doi.org/10.1093/nar/gkz1178
https://doi.org/10.1093/nar/gkz1178
Autor:
Elisabeth A. Marnik, Miguel V. Almeida, P. Giselle Cipriani, George Chung, Edoardo Caspani, Emil Karaulanov, Hin Hark Gan, John Zinno, Ida J. Isolehto, Fridolin Kielisch, Falk Butter, Catherine S. Sharp, Roisin M. Flanagan, Frederic X. Bonnet, Fabio Piano, René F. Ketting, Kristin C. Gunsalus, Dustin L. Updike
Publikováno v:
PLoS genetics. 18(6)
LOTUS and Tudor domain containing proteins have critical roles in the germline. Proteins that contain these domains, such as Tejas/Tapas in Drosophila, help localize the Vasa helicase to the germ granules and facilitate piRNA-mediated transposon sile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad6529e0dba67fa8e6207196d5ec0e4
https://pubmed.ncbi.nlm.nih.gov/35657999
https://pubmed.ncbi.nlm.nih.gov/35657999
Autor:
Marnik Ea, Almeida Mv, Patricia G. Cipriani, George Chung, Dustin L. Updike, René F. Ketting, Emil Karaulanov, Butter F, Catherine S. Sharp, Hin Hark Gan, Caspani E, Kristin C. Gunsalus, Fabio Piano, John Zinno
LOTUS and Tudor domain containing proteins have critical roles in the germline. Proteins that contain these domains, such as Tejas/Tapas in Drosophila, help localize Vasa to the germ granules and facilitate piRNA-mediated transposon silencing. The ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e8c9bc10ecdeb28a8b77845214d59e
https://doi.org/10.1101/2021.06.18.448978
https://doi.org/10.1101/2021.06.18.448978
Autor:
Dustin L. Updike, Sarah E. Holbrook, J. Heath Fuqua, Jesse D. Rochester, Catherine S. Sharp, Emily L. Xu, Elisabeth A. Marnik
Publikováno v:
Genetics
Vasa homologs are ATP-dependent DEAD-box helicases, multipotency factors, and critical components that specify and protect the germline. They regulate translation, amplify piRNAs, and act as RNA solvents; but, the limited availability of mutagenesis-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72afaf4b8029c361315d97c898755a6e
http://europepmc.org/articles/PMC6827368
http://europepmc.org/articles/PMC6827368