Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dustin Elwood"'
Autor:
Alison Generotti, Ryne Contreras, Brenden Zounes, Eric Schade, Andrea Kemme, Yatish Rane, Xinggang Liu, Dustin Elwood, Katherine Schultheis, Jeremy Marston, Jay McCoy, Kate Broderick, Paul Fisher
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102070- (2023)
Intradermal delivery of DNA vaccines via electroporation (ID-EP) has shown clinical promise, but the use of needle electrodes is typically required to achieve consistent results. Here, delivery of a DNA vaccine targeting the Middle East Respiratory S
Externí odkaz:
https://doaj.org/article/410d3ecf4cff4763b4f611534e4e5a2e
Autor:
Viviane M. Andrade, Aaron Christensen-Quick, Joseph Agnes, Jared Tur, Charles Reed, Richa Kalia, Idania Marrero, Dustin Elwood, Katherine Schultheis, Mansi Purwar, Emma Reuschel, Trevor McMullan, Patrick Pezzoli, Kim Kraynyak, Albert Sylvester, Mammen P. Mammen, Pablo Tebas, J. Joseph Kim, David B. Weiner, Trevor R. F. Smith, Stephanie J. Ramos, Laurent M. Humeau, Jean D. Boyer, Kate E. Broderick
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-4 (2021)
Abstract Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine-induced immunity. Here we compared humoral and cellular responses again
Externí odkaz:
https://doaj.org/article/861f6b3de24f4eca965d9adae892bcdd
Autor:
Trevor R. F. Smith, Ami Patel, Stephanie Ramos, Dustin Elwood, Xizhou Zhu, Jian Yan, Ebony N. Gary, Susanne N. Walker, Katherine Schultheis, Mansi Purwar, Ziyang Xu, Jewell Walters, Pratik Bhojnagarwala, Maria Yang, Neethu Chokkalingam, Patrick Pezzoli, Elizabeth Parzych, Emma L. Reuschel, Arthur Doan, Nicholas Tursi, Miguel Vasquez, Jihae Choi, Edgar Tello-Ruiz, Igor Maricic, Mamadou A. Bah, Yuanhan Wu, Dinah Amante, Daniel H. Park, Yaya Dia, Ali Raza Ali, Faraz I. Zaidi, Alison Generotti, Kevin Y. Kim, Timothy A. Herring, Sophia Reeder, Viviane M. Andrade, Karen Buttigieg, Gan Zhao, Jiun-Ming Wu, Dan Li, Linlin Bao, Jiangning Liu, Wei Deng, Chuan Qin, Ami Shah Brown, Makan Khoshnejad, Nianshuang Wang, Jacqueline Chu, Daniel Wrapp, Jason S. McLellan, Kar Muthumani, Bin Wang, Miles W. Carroll, J. Joseph Kim, Jean Boyer, Daniel W. Kulp, Laurent M. P. F. Humeau, David B. Weiner, Kate E. Broderick
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
There is currently no licensed SARS-CoV-2 vaccine. Here, the authors generate an optimized DNA vaccine candidate encoding the SARS-CoV-2 spike antigen, demonstrating induction of specific T cells and neutralizing antibody responses in mice and guinea
Externí odkaz:
https://doaj.org/article/0814bda6deff4859a14eda518fea5941
Autor:
Ami Patel, Jewell N. Walters, Emma L. Reuschel, Katherine Schultheis, Elizabeth Parzych, Ebony N. Gary, Igor Maricic, Mansi Purwar, Zeena Eblimit, Susanne N. Walker, Diana Guimet, Pratik Bhojnagarwala, Opeyemi S. Adeniji, Arthur Doan, Ziyang Xu, Dustin Elwood, Sophia M. Reeder, Laurent Pessaint, Kevin Y. Kim, Anthony Cook, Neethu Chokkalingam, Brad Finneyfrock, Edgar Tello-Ruiz, Alan Dodson, Jihae Choi, Alison Generotti, John Harrison, Nicholas J. Tursi, Viviane M. Andrade, Yaya Dia, Faraz I. Zaidi, Hanne Andersen, Mohamed Abdel-Mohsen, Mark G. Lewis, Kar Muthumani, J. Joseph Kim, Daniel W. Kulp, Laurent M. Humeau, Stephanie J. Ramos, Trevor R.F. Smith, David B. Weiner, Kate E. Broderick
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100420- (2021)
Summary: Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has had a dramatic global impact on public health and social and economic infrastructures. Here, we assess the immunogenicity and anamnestic protective efficacy in rhesus m
Externí odkaz:
https://doaj.org/article/b251aab9f925454e8c8c047ebbca4faa
Autor:
Jingjing Jiang, Stephanie J. Ramos, Preeti Bangalore, Dustin Elwood, Kathleen A. Cashman, Sagar B. Kudchodkar, Katherine Schultheis, Holly Pugh, Jewell Walters, Jared Tur, Jian Yan, Ami Patel, Kar Muthumani, Connie S. Schmaljohn, David B. Weiner, Laurent M. Humeau, Kate E. Broderick
Publikováno v:
Viruses, Vol 13, Iss 3, p 382 (2021)
The emergence of multiple concurrent infectious diseases localized in the world creates a complex burden on global public health systems. Outbreaks of Ebola, Lassa, and Marburg viruses in overlapping regions of central and West Africa and the co-circ
Externí odkaz:
https://doaj.org/article/06292c7bc4954bc78774733aa152463f
Autor:
Jewell Walters, Brian Nguyen, David B. Weiner, J. Joseph Kim, Trevor R.F. Smith, Abhijeet J Kulkarni, Viviane M Andrade, Alison Generotti, Emma L. Reuschel, Laurent Humeau, Dustin Elwood, Ebony N. Gary, Stephanie Ramos, Arthur Doan, Igor Maricic, Zeena Eblimit, Elizabeth Parzych, Drew Frase, Ami Patel, Katherine Schultheis, Mansi Purwar, Kate E. Broderick, Faraz I. Zaidi, Blake Schouest
Publikováno v:
Vaccine. 40(21)
SUMMARYThe enhanced transmissibility and immune evasion associated with emerging SARS-CoV-2 variants demands the development of next-generation vaccines capable of inducing superior protection amid a shifting pandemic landscape. Since a portion of th
Autor:
Dinah Amante, Maria Yang, Jared Tur, Arthur Doan, Igor Maricic, Blake Schouest, Zeena Eblimit, Patrick Pezzoli, Trevor R.F. Smith, Megan Lok, Katherine Schultheis, Swagata Kar, David B. Weiner, Maciel Porto, Brittany Spence, Fader J, Viviane M Andrade, J. Joseph Kim, Richa Kalia, Laurent Humeau, Ferrer R, Dustin Elwood, Stephanie Ramos, Charles C. Reed, Kate Broderick, Horn H, Miguel Vazquez, Bradette H, Jewell Walters, Brandon Narvaez
Here we have employed SynCon® design technology to construct a DNA vaccine expressing a pan-Spike immunogen (INO-4802) to induce broad immunity across SARS-CoV-2 variants of concern (VOC). Compared to WT and VOC-matched vaccines which showed reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e1492c32118edc0ca564439e5b1697
https://doi.org/10.1101/2021.05.11.443592
https://doi.org/10.1101/2021.05.11.443592
Autor:
Joseph Agnes, Aaron Christensen-Quick, Emma L. Reuschel, Kim Kraynyak, Jared Tur, Mammen P Mammen, Viviane M Andrade, Trevor R.F. Smith, Katherine Schultheis, Dustin Elwood, Patrick Pezzoli, Jean D. Boyer, Idania Marrero, Laurent Humeau, Stephanie Ramos, David B. Weiner, J. Joseph Kim, Trevor McMullan, Albert Sylvester, Pablo Tebas, Charles C. Reed, Kate E. Broderick, Mansi Purwar, Richa Kalia
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-4 (2021)
NPJ Vaccines
NPJ Vaccines
Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine-induced immunity. Here we compared humoral and cellular responses against SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99099b9b80749aac455ddd7326015284
https://doi.org/10.1101/2021.04.14.439719
https://doi.org/10.1101/2021.04.14.439719
Autor:
Jared Tur, Sagar B. Kudchodkar, Jingjing Jiang, Ami Patel, Dustin Elwood, Kate E. Broderick, Connie S. Schmaljohn, Karuppiah Muthumani, Kathleen A. Cashman, Jian Yan, Holly Pugh, Katherine Schultheis, Preeti Bangalore, David B. Weiner, Laurent Humeau, Stephanie Ramos, Jewell Walters
Publikováno v:
Viruses, Vol 13, Iss 382, p 382 (2021)
Viruses
Volume 13
Issue 3
Viruses
Volume 13
Issue 3
The emergence of multiple concurrent infectious diseases localized in the world creates a complex burden on global public health systems. Outbreaks of Ebola, Lassa, and Marburg viruses in overlapping regions of central and West Africa and the co-circ
Autor:
Mohamed Abdel-Mohsen, Laurent Humeau, Stephanie Ramos, J. Joseph Kim, Arthur Doan, Edgar Tello-Ruiz, Mansi Purwar, Anthony L. Cook, Faraz I. Zaidi, Brad Finneyfrock, Diana Guimet, Yaya Dia, Kate E. Broderick, Dustin Elwood, Alan Dodson, Viviane M Andrade, Laurent Pessaint, Jewell Walters, Ami Patel, Elizabeth Parzych, Neethu Chokkalingam, Jihae Choi, Ziyang Xu, Emma L. Reuschel, Igor Maricic, Trevor R.F. Smith, Zeena Eblimit, Opeyemi S. Adeniji, Kevin Kim, Ebony N. Gary, Sophia M. Reeder, Mark G. Lewis, John Harrison, Daniel W. Kulp, Susanne Walker, Alison Generotti, David B. Weiner, Karuppiah Muthumani, Nicholas J. Tursi, Hanne Leth Andersen, Katherine Schultheis, Pratik Bhojnagarwala
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 10, Pp 100420-(2021)
Cell Reports Medicine, Vol 2, Iss 10, Pp 100420-(2021)
Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has had a dramatic global impact on public health and social and economic infrastructures. Here, we assess the immunogenicity and anamnestic protective efficacy in rhesus macaques o