Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dustin C Ernst"'
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197703 (2018)
Microorganisms respond to a variety of metabolic perturbations by repurposing or recruiting pathways to reroute metabolic flux and overcome the perturbation. Elimination of the 2-dehydropantoate 2-reductase, PanE, both reduces total coenzyme A (CoA)
Externí odkaz:
https://doaj.org/article/57f94e155572451eb27c09c90490d89b
Autor:
Arnaud Taton, Tami S. Gilderman, Dustin C. Ernst, Carla A. Omaga, Lucas A. Cohen, Camilo Rey-Bedon, James W. Golden, Susan S. Golden
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The cyanobacterium Synechococcus elongatus PCC 7942 produces an active prokaryotic Argonaute nuclease, SeAgo, whose function is unknown. Here, we show that SeAgo reduces natural transformation and prevents the maintenance of RSF1010 replicon
Externí odkaz:
https://doaj.org/article/a0bc37e5588d411096011710c169c0ee
Autor:
Jeffrey A. Swan, Colby R. Sandate, Archana G. Chavan, Alfred M. Freeberg, Diana Etwaru, Dustin C. Ernst, Joseph G. Palacios, Susan S. Golden, Andy LiWang, Gabriel C. Lander, Carrie L. Partch
Publikováno v:
Nat Struct Mol Biol
Nature structural & molecular biology, vol 29, iss 8
Nature structural & molecular biology, vol 29, iss 8
The AAA(+) family member KaiC is the central pacemaker for circadian rhythms in the cyanobacterium Synechococcus elongatus. Composed of two hexameric rings of adenosine triphosphatase (ATPase) domains with tightly coupled activities, KaiC undergoes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85023c29e4811f25327ef7284b586e99
https://doi.org/10.1038/s41594-022-00803-w
https://doi.org/10.1038/s41594-022-00803-w
Autor:
Andrew J. Borchert, Jacquelyn M. Walejko, Adrien Le Guennec, Dustin C. Ernst, Arthur S. Edison, Diana M. Downs
Publikováno v:
Metabolites, Vol 10, Iss 1, p 12 (2019)
In Salmonella enterica, 2-aminoacrylate (2AA) is a reactive enamine intermediate generated during a number of biochemical reactions. When the 2-iminobutanoate/2-iminopropanoate deaminase (RidA; EC: 3.5.99.10) is eliminated, 2AA accumulates and inhibi
Externí odkaz:
https://doaj.org/article/a715b7ba2164471b8ff1bcda125798d3
Publikováno v:
Yeast
The RidA subfamily of the Rid (YjgF/YER057c/UK114) superfamily of proteins is broadly distributed and found in all domains of life. RidA proteins are enamine/imine deaminases. In the organisms that have been investigated, lack of RidA results in accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9775949041e3e1877e73dc90e00bd0
https://doi.org/10.1002/yea.3670
https://doi.org/10.1002/yea.3670
Autor:
Jeffrey A. Swan, Sarvind Tripathi, Joel Heisler, Clive R. Bagshaw, Susan S. Golden, Priya Crosby, Andy LiWang, Archana G. Chavan, Cigdem Sancar, Joseph G. Palacios, Carrie L. Partch, Rebecca K. Spangler, Mingxu Fang, Dustin C. Ernst
Publikováno v:
Science (New York, N.Y.). 374(6564)
Circadian clocks control gene expression to provide an internal representation of local time. We report reconstitution of a complete cyanobacterial circadian clock in vitro, including the central oscillator, signal transduction pathways, downstream t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2f6d12aef78af34b1e21cd26011d99
https://pubmed.ncbi.nlm.nih.gov/34875245
https://pubmed.ncbi.nlm.nih.gov/34875245
Autor:
Dustin C. Ernst, Diana Etwaru, Colby R. Sandate, Archana G. Chavan, Carrie L. Partch, Susan S. Golden, Jeffrey A. Swan, Gabriel C. Lander, Joseph G. Palacios, Andy LiWang, Alfred M. Freeberg
The AAA+ protein KaiC is the central pacemaker for cyanobacterial circadian rhythms. Composed of two hexameric rings with tightly coupled activities, KaiC undergoes changes in autophosphorylation on its C-terminal (CII) domain that restrict binding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b60a087e32ae2672a3d5ec84c865f9
https://doi.org/10.1101/2021.09.14.460370
https://doi.org/10.1101/2021.09.14.460370
Autor:
Sarvind Tripathi, Jeffrey A. Swan, Dustin C. Ernst, Joel Heisler, Cigdem Sancar, Andy LiWang, Susan S. Golden, Clive R. Bagshaw, Rebecca K. Spangler, Carrie L. Partch, Priya Crosby, Joseph G. Palacios
The histidine kinase SasA enhances robustness of circadian rhythms in the cyanobacterium S. elongatus by temporally controlling expression of the core clock components, kaiB and kaiC. Here we show that SasA also engages directly with KaiB and KaiC pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a4f8efec3365f2607d2bf1ce0845a28
https://doi.org/10.1101/2020.06.17.158394
https://doi.org/10.1101/2020.06.17.158394
Autor:
Archana G. Chavan, Mingxu Fang, Cigdem Sancar, Susan S. Golden, Andy LiWang, Dustin C. Ernst, Carrie L. Partch
Circadian clocks control gene expression in the complex milieu of cells. Here, we reconstituted under defined conditions in vitro the cyanobacterial circadian clock system which includes an oscillator, signal-transduction pathways, transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9164b7f8b964a3125393e573404143bc
https://doi.org/10.1101/2020.06.18.158576
https://doi.org/10.1101/2020.06.18.158576
Autor:
Jeffrey A. Swan, Colby R. Sandate, Alfred M. Freeberg, Joel C. Heisler, Diana L. Etwaru, Cigdem Sancar, Dustin C. Ernst, Joseph G. Palacios, Clive R. Bagshaw, Archana G. Chavan, Susan S. Golden, Andy LiWang, Gabriel C. Lander, Carrie L. Partch
Publikováno v:
Biophysical Journal. 121:335a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eae67ec8f89493e337e8137615b4593
https://doi.org/10.1016/j.bpj.2021.11.1065
https://doi.org/10.1016/j.bpj.2021.11.1065