Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Dusten Unruh"'
Autor:
Michael R. Drumm, Wenxia Wang, Thomas K. Sears, Kirsten Bell-Burdett, Rodrigo Javier, Kristen Y. Cotton, Brynna Webb, Kayla Byrne, Dusten Unruh, Vineeth Thirunavu, Jordain Walshon, Alicia Steffens, Kathleen McCortney, Rimas V. Lukas, Joanna J. Phillips, Esraa Mohamed, John D. Finan, Lucas Santana-Santos, Amy B. Heimberger, Colin K. Franz, Jonathan Kurz, Jessica W. Templer, Geoffrey T. Swanson, Craig Horbinski
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 (IDHmut) are more likely than IDH–wild type (IDHwt) gliomas to cause
Externí odkaz:
https://doaj.org/article/7fc24269c7a640d7a68744806d41d5ca
Autor:
Dusten Unruh, Craig Horbinski
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Tissue factor (TF) is the primary initiator of the coagulation cascade, though its effects extend well beyond hemostasis. When TF binds to Factor VII, the resulting TF:FVIIa complex can proteolytically cleave transmembrane G protein-coupled
Externí odkaz:
https://doaj.org/article/afb45ea96b0b42e8b68898f701204135
Autor:
Susanna H M Sluka, Alexander Akhmedov, Johannes Vogel, Dusten Unruh, Vladimir Y Bogdanov, Giovanni G Camici, Thomas F Lüscher, Wolfram Ruf, Felix C Tanner
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97793 (2014)
Tissue factor (TF) triggers blood coagulation and is translated from two mRNA splice isoforms, encoding membrane-anchored full-length TF (flTF) and soluble alternatively-spliced TF (asTF). The complete knockout of TF in mice causes embryonic lethalit
Externí odkaz:
https://doaj.org/article/473d2bf9dbe34145804b8f3da47eb90c
Autor:
Michael Drumm, Wenxia Wang, Thomas K. Sears, Kirsten Bell-Burdett, Rodrigo Javier, Kristen Y. Cotton, Brynna T. Webb, Kayla T. Byrne, Dusten Unruh, Vineeth Thirunavu, Jordain Walshon, Alicia Steffens, Kathleen McCortney, Rimas V. Lukas, Joanna J. Phillips, Esraa Mohamed, John D. Finan, Lucas Santana-Santos, Amy B. Heimberger, Colin K. Franz, Jonathan E. Kurz, Jessica W. Templer, Geoffrey T. Swanson, Craig Horbinski
Publikováno v:
The Journal of clinical investigation, vol 133, iss 12
Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 (IDHmut) are more likely than IDH-wild type (IDHwt) gliomas to cause se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125e96da5b909fb444616a484ece9056
https://escholarship.org/uc/item/1hp8c54d
https://escholarship.org/uc/item/1hp8c54d
Autor:
Rintaro Hashizume, Ali Shilatifard, Lihua Zou, Oren J. Becher, Sriram Venneti, Stewart Goldman, Rishi Lulla, Nitin R. Wadhwani, Akihide Kondo, Kathryn L. Laurie, Vera Gorbunova, Andrei Seluanov, Xiao Tian, Angel M. Carcaboso, Jonathan B. Lamano, Yosuke Shimazu, Andrea Piunti, Quanhong Ma, Ali Zhang, Xingyao He, Takahiro Sasaki, Dusten Unruh, Nundia Louis, Hiroaki Katagi
Supplementary Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160d9f9297cb71995dbb552d090cdd11
https://doi.org/10.1158/1078-0432.22472546.v1
https://doi.org/10.1158/1078-0432.22472546.v1
Autor:
Rintaro Hashizume, Ali Shilatifard, Lihua Zou, Oren J. Becher, Sriram Venneti, Stewart Goldman, Rishi Lulla, Nitin R. Wadhwani, Akihide Kondo, Kathryn L. Laurie, Vera Gorbunova, Andrei Seluanov, Xiao Tian, Angel M. Carcaboso, Jonathan B. Lamano, Yosuke Shimazu, Andrea Piunti, Quanhong Ma, Ali Zhang, Xingyao He, Takahiro Sasaki, Dusten Unruh, Nundia Louis, Hiroaki Katagi
Supplementary Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d29940c7d6691143465d06c92a5cb3
https://doi.org/10.1158/1078-0432.22472540.v1
https://doi.org/10.1158/1078-0432.22472540.v1
Autor:
Craig Horbinski, C. David James, Jann N. Sarkaria, Denise M. Scholtens, Amanda Saratsis, Kathleen McCortney, Rodrigo Javier, Qazi F. Haider, Yuping D. Li, Jonathan Lamano, Michael Drumm, Brian Wray, Snezana Mirkov, Dusten Unruh
description of the methods in the supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b406714dda519f644197eb1623543b
https://doi.org/10.1158/1078-0432.22473948
https://doi.org/10.1158/1078-0432.22473948
Autor:
Rintaro Hashizume, Ali Shilatifard, Lihua Zou, Oren J. Becher, Sriram Venneti, Stewart Goldman, Rishi Lulla, Nitin R. Wadhwani, Akihide Kondo, Kathryn L. Laurie, Vera Gorbunova, Andrei Seluanov, Xiao Tian, Angel M. Carcaboso, Jonathan B. Lamano, Yosuke Shimazu, Andrea Piunti, Quanhong Ma, Ali Zhang, Xingyao He, Takahiro Sasaki, Dusten Unruh, Nundia Louis, Hiroaki Katagi
Purpose:Radiotherapy (RT) has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all patients show evidence of disease progression within months of completing RT. No further clinical benefit has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45a5914ca6df0f05a218b77d4169284
https://doi.org/10.1158/1078-0432.c.6528257
https://doi.org/10.1158/1078-0432.c.6528257
Autor:
Craig Horbinski, C. David James, Jann N. Sarkaria, Denise M. Scholtens, Amanda Saratsis, Kathleen McCortney, Rodrigo Javier, Qazi F. Haider, Yuping D. Li, Jonathan Lamano, Michael Drumm, Brian Wray, Snezana Mirkov, Dusten Unruh
Purpose:Gliomas with isocitrate dehydrogenase 1 mutations (IDH1mut) are less aggressive than IDH1 wild-type (IDH1wt) gliomas and have global genomic hypermethylation. Yet it is unclear how specific hypermethylation events contribute to the IDH1mut ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8f2e3dd32fac624e6c05f3a0bb1219
https://doi.org/10.1158/1078-0432.c.6528648.v1
https://doi.org/10.1158/1078-0432.c.6528648.v1
Autor:
Craig Horbinski, C. David James, Jann N. Sarkaria, Denise M. Scholtens, Amanda Saratsis, Kathleen McCortney, Rodrigo Javier, Qazi F. Haider, Yuping D. Li, Jonathan Lamano, Michael Drumm, Brian Wray, Snezana Mirkov, Dusten Unruh
Supplementary data figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0fc8d182505f8b9d1a39ba656e5597
https://doi.org/10.1158/1078-0432.22473951
https://doi.org/10.1158/1078-0432.22473951