Challenges of enzyme therapy: Why two players are better than one.

Autor: Cuoghi S; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Caraffi R; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Clinical and Experimental Medicine PhD Program, Department of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy., Anderlini A; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Baraldi C; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Enzo E; Centre for Regenerative Medicine 'Stefano Ferrari', University of Modena and Reggio Emilia, Modena, Italy., Vandelli MA; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Tosi G; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Ruozi B; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Duskey JT; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Ottonelli I; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Publikováno v: Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology [Wiley Interdiscip Rev Nanomed Nanobiotechnol] 2024 Jul-Aug; Vol. 16 (4), pp. e1979.

Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington's disease.

Autor: Birolini G; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy., Valenza M; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy. Electronic address: marta.valenza@unimi.it., Ottonelli I; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Talpo F; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy., Minoli L; Pathology Department, Evotec, 37135 Verona, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy., Cappelleri A; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy., Bombaci M; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy., Caccia C; Unit of Medical Genetics and Neurogenetics. Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy., Canevari C; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy., Trucco A; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy., Leoni V; Laboratory of Clinical Chemistry, Hospital Pio XI of Desio, ASST-Brianza and Department of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy., Passoni A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy., Favagrossa M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy., Nucera MR; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy., Colombo L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy., Paltrinieri S; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy., Bagnati R; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy., Duskey JT; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Caraffi R; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Vandelli MA; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Taroni F; Unit of Medical Genetics and Neurogenetics. Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy., Salmona M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy., Scanziani E; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy., Biella G; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy., Ruozi B; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Tosi G; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Cattaneo E; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy. Electronic address: elena.cattaneo@unimi.it.

Publikováno v: Pharmacological research [Pharmacol Res] 2023 Aug; Vol. 194, pp. 106823. Date of Electronic Publication: 2023 Jun 17.

"Combo" Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury.

Autor: Moretti M; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy., Caraffi R; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Lorenzini L; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy., Ottonelli I; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Sannia M; IRET Foundation, Ozzano Emilia, 40064 Bologna, Italy., Alastra G; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy., Baldassarro VA; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy.; Health Science and Technologies, Interdepartmental Center for Industrial Research (HST-ICIR), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy., Giuliani A; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy., Duskey JT; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Cescatti M; IRET Foundation, Ozzano Emilia, 40064 Bologna, Italy., Ruozi B; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Aloe L; IRET Foundation, Ozzano Emilia, 40064 Bologna, Italy., Vandelli MA; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Giardino L; Department of Veterinary Medical Science (DIMEVET), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy.; IRET Foundation, Ozzano Emilia, 40064 Bologna, Italy., Tosi G; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy., Calzà L; Health Science and Technologies, Interdepartmental Center for Industrial Research (HST-ICIR), University of Bologna, Ozzano Emilia, 40064 Bologna, Italy.; Montecatone Rehabilitation Institute, 40026 Imola, Italy.; Department of Pharmacy and Biotechnology (FaBit), University of Bologna, 40126 Bologna, Italy.

Publikováno v: Cells [Cells] 2023 May 06; Vol. 12 (9). Date of Electronic Publication: 2023 May 06.

Nanowired Delivery of Curcumin Attenuates Methamphetamine Neurotoxicity and Elevates Levels of Dopamine and Brain-Derived Neurotrophic Factor.

Autor: Ottonelli I; Te.far.t.I, Dept of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Sharma A; International Experimental Central Nervous System Injury & Repair (IECNSIR), Surgical Sciences, Anesthesiology & Intensive Care Med., Uppsala University Hospital, Uppsala University, Uppsala, Sweden., Ruozi B; Te.far.t.I, Dept of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Tosi G; Te.far.t.I, Dept of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Duskey JT; Te.far.t.I, Dept of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Vandelli MA; Te.far.t.I, Dept of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy., Lafuente JV; LaNCE, Department Neuroscience, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain., Nozari A; Anesthesia and Critical Care, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Muresanu DF; 'RoNeuro' Institute for Neurological Research and Diagnosis, Cluj-Napoca, Romania.; Clinical Neurosciences, University of Medicine & Pharmacy, Cluj-Napoca, Romania., Buzoianu AD; Department of Clinical Pharmacology and Toxicology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania., Tian ZR; Dept. Chemistry & Biochemistry, University of Arkansas, Fayetteville, AR, USA., Zhang Z; Department of Neurosurgery, Chinese Medicine Hospital of Guangdong Province; The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China., Li C; Department of Neurosurgery, Chinese Medicine Hospital of Guangdong Province; The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China., Feng L; Department of Neurology, Bethune International Peace Hospital, Zhongshan Road (West), Shijiazhuang, Hebei Province, China., Wiklund L; International Experimental Central Nervous System Injury & Repair (IECNSIR), Surgical Sciences, Anesthesiology & Intensive Care Med., Uppsala University Hospital, Uppsala University, Uppsala, Sweden., Sharma HS; International Experimental Central Nervous System Injury & Repair (IECNSIR), Surgical Sciences, Anesthesiology & Intensive Care Med., Uppsala University Hospital, Uppsala University, Uppsala, Sweden. Sharma@surgsci.uu.se.

Publikováno v: Advances in neurobiology [Adv Neurobiol] 2023; Vol. 32, pp. 385-416.

Quantitative comparison of the protein corona of nanoparticles with different matrices.

Autor: Ottonelli I; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Clinical and Experimental Medicine PhD Program, Department of Biomedical, Metabolic, and Neural Sciences, Via Campi 287, University of Modena and Reggio Emilia, 41125 Modena, Italy., Duskey JT; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy., Genovese F; CIGS, Centro Interdipartimentale Grandi Strumenti, Via Campi 213A, University of Modena and Reggio Emilia, 41125 Modena, Italy., Pederzoli F; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy., Caraffi R; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy., Valenza M; Department of Biosciences, Via Giovanni Celoria 26, University of Milan, 20133 Milan, Italy., Tosi G; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy., Vandelli MA; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy., Ruozi B; Nanotech Lab, Te.Far.T.I., Department of Life Sciences, Via Campi 103, University of Modena and Reggio Emilia, 41125 Modena, Italy.

Publikováno v: International journal of pharmaceutics: X [Int J Pharm X] 2022 Oct 21; Vol. 4, pp. 100136. Date of Electronic Publication: 2022 Oct 21 (Print Publication: 2022).