Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dusica Vidović"'
Autor:
Braden T. Tierney, Jonathan Foox, Krista A. Ryon, Daniel Butler, Namita Damle, Benjamin G. Young, Christopher Mozsary, Kristina M. Babler, Xue Yin, Yamina Carattini, David Andrews, Alexander G. Lucaci, Natasha Schaefer Solle, Naresh Kumar, Bhavarth Shukla, Dušica Vidović, Benjamin Currall, Sion L. Williams, Stephan C. Schürer, Mario Stevenson, Ayaaz Amirali, Cynthia Campos Beaver, Erin Kobetz, Melinda M. Boone, Brian Reding, Jennifer Laine, Samuel Comerford, Walter E. Lamar, John J. Tallon, Jeremy Wain Hirschberg, Jacqueline Proszynski, Gabriel Al Ghalith, Kübra Can Kurt, Mark E. Sharkey, George M. Church, George S. Grills, Helena M. Solo-Gabriele, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Wastewater is a geospatially- and temporally-linked microbial fingerprint of a given population, making it a potentially valuable tool for tracking public health across locales and time. Here, we integrate targeted and bulk RNA sequencing (N
Externí odkaz:
https://doaj.org/article/e0c84d08c6104aac859de15f2159b913
Autor:
Jens Hansen, Yuguang Xiong, Mustafa M. Siddiq, Priyanka Dhanan, Bin Hu, Bhavana Shewale, Arjun S. Yadaw, Gomathi Jayaraman, Rosa E. Tolentino, Yibang Chen, Pedro Martinez, Kristin G. Beaumont, Robert Sebra, Dusica Vidovic, Stephan C. Schürer, Joseph Goldfarb, James M. Gallo, Marc R. Birtwistle, Eric A. Sobie, Evren U. Azeloglu, Seth I. Berger, Angel Chan, Christoph Schaniel, Nicole C. Dubois, Ravi Iyengar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Drug-induced gene expression profiles can identify potential mechanisms of toxicity. We focus on obtaining signatures for cardiotoxicity of FDA-approved tyrosine kinase inhibitors (TKIs) in human induced-pluripotent-stem-cell-derived cardiom
Externí odkaz:
https://doaj.org/article/5c705931ae3749d8b0d5c464d5e8d788
Autor:
Kristina M. Babler, Mark E. Sharkey, Samantha Abelson, Ayaaz Amirali, Aymara Benitez, Gabriella A. Cosculluela, George S. Grills, Naresh Kumar, Jennifer Laine, Walter Lamar, Erik D. Lamm, Jiangnan Lyu, Christopher E. Mason, Philip M. McCabe, Joshi Raghavender, Brian D. Reding, Matthew A. Roca, Stephan C. Schürer, Mario Stevenson, Angela Szeto, John J. Tallon, Dusica Vidović, Yalda Zarnegarnia, Helena M. Solo-Gabriele
Publikováno v:
Science of The Total Environment. 867:161423
Autor:
Vincent T. Metzger, Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Cristian G. Bologa, Anna Waller, Stephan C. Schürer, Dušica Vidović, Keith J. Kelleher, Timothy K. Sheils, Lars Juhl Jensen, Christophe G. Lambert, Tudor I. Oprea, Jeremy S. Edwards
Publikováno v:
PeerJ, Vol 12, p e17470 (2024)
TIN-X (Target Importance and Novelty eXplorer) is an interactive visualization tool for illuminating associations between diseases and potential drug targets and is publicly available at newdrugtargets.org. TIN-X uses natural language processing to i
Externí odkaz:
https://doaj.org/article/960d5f8e591045c1b0baec822e03ab67
Autor:
Sean M. Gross, Mark A. Dane, Rebecca L. Smith, Kaylyn L. Devlin, Ian C. McLean, Daniel S. Derrick, Caitlin E. Mills, Kartik Subramanian, Alexandra B. London, Denis Torre, John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Cemal Erdem, Nicholas Lyons, Ted Natoli, Sarah Pessa, Xiaodong Lu, James Mullahoo, Jonathan Li, Miriam Adam, Brook Wassie, Moqing Liu, David F. Kilburn, Tiera A. Liby, Elmar Bucher, Crystal Sanchez-Aguila, Kenneth Daily, Larsson Omberg, Yunguan Wang, Connor Jacobson, Clarence Yapp, Mirra Chung, Dusica Vidovic, Yiling Lu, Stephan Schurer, Albert Lee, Ajay Pillai, Aravind Subramanian, Malvina Papanastasiou, Ernest Fraenkel, Heidi S. Feiler, Gordon B. Mills, Jake D. Jaffe, Avi Ma’ayan, Marc R. Birtwistle, Peter K. Sorger, James E. Korkola, Joe W. Gray, Laura M. Heiser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Comprehensive profiling of ligand-induced perturbation responses of the MCF10A mammary epithelial cell line provides an exhaustive resource for identification of the molecular basis of cellular phenotypes.
Externí odkaz:
https://doaj.org/article/50400b000ed946209179e826cd85298c
Autor:
Marcin Pilarczyk, Mehdi Fazel-Najafabadi, Michal Kouril, Behrouz Shamsaei, Juozas Vasiliauskas, Wen Niu, Naim Mahi, Lixia Zhang, Nicholas A. Clark, Yan Ren, Shana White, Rashid Karim, Huan Xu, Jacek Biesiada, Mark F. Bennett, Sarah E. Davidson, John F. Reichard, Kurt Roberts, Vasileios Stathias, Amar Koleti, Dusica Vidovic, Daniel J. B. Clarke, Stephan C. Schürer, Avi Ma’ayan, Jarek Meller, Mario Medvedovic
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that do not require programming skills. Here the authors present an integrative web-based platfor
Externí odkaz:
https://doaj.org/article/08ffc15267ee4c3faac75343be39e39f
Autor:
Yuguang Xiong, Tong Liu, Tong Chen, Jens Hansen, Bin Hu, Yibang Chen, Gomathi Jayaraman, Stephan Schürer, Dusica Vidovic, Joseph Goldfarb, Eric A. Sobie, Marc R. Birtwistle, Ravi Iyengar, Hong Li, Evren U. Azeloglu
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-11 (2022)
Measurement(s) protein expression profiling Technology Type(s) mass spectrometry assay Factor Type(s) Individual proteome • Kinase inhibitors Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the reported dat
Externí odkaz:
https://doaj.org/article/3417c9ff341948ffb259c8e4c42eb730
Autor:
Yu Lin, Saurabh Mehta, Hande Küçük-McGinty, John Paul Turner, Dusica Vidovic, Michele Forlin, Amar Koleti, Dac-Trung Nguyen, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, Caty Chung, Christopher Mader, Ubbo Visser, Jeremy J. Yang, Cristian G. Bologa, Tudor I. Oprea, Stephan C. Schürer
Publikováno v:
Journal of Biomedical Semantics, Vol 8, Iss 1, Pp 1-16 (2017)
Abstract Background One of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein target. However, only a small subset of potentially druggable targets has attracted significant
Externí odkaz:
https://doaj.org/article/c7f21332499a4a20a9198a03f5457353
Publikováno v:
Journal of the Serbian Chemical Society, Vol 68, Iss 4-5, Pp 401-408 (2003)
In earlier studies it was established that internal molecular energies (Eint) of alkanes can be reproduced, in an approximate yet reliable manner, by means of a molecular-graph-based structure-descriptor U. It was also established that U is linearly
Externí odkaz:
https://doaj.org/article/9c58a0bd5fef424a84ed62586e9315b2
Publikováno v:
Journal of the Serbian Chemical Society, Vol 67, Iss 2, Pp 87-97 (2002)
The connectivity index of an organic molecule whose molecular graph is G is defined as C(l) = S(dudu)1, where du is the degree of the vertex u in G, where the summation goes over all pairs of adjacent vertices of G and where l is a pertinently chosen
Externí odkaz:
https://doaj.org/article/16e49c09a2eb46a1a15f314810453669