Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dushyant V. Patel"'
Autor:
Divya M. Teli, Mahesh T. Chhabria, Dushyant V. Patel, Nirav R. Patel, Ashish M. Kanhed, Amisha Vora, Bhavik S. Shah, Mange Ram Yadav
Publikováno v:
International Journal of Quantitative Structure-Property Relationships. 6:58-77
A novel coronavirus is the causative agent identified for the current COVID-19 outbreak. Globally, more than 43 million people have been infected by this virus. The total number of deaths has surpassed 1.6 million across 210 countries due to the curr
Autor:
Priyanka S Thakor, Kirti V. Patel, Mange Ram Yadav, Anshuman Sinha, Navnit K Prajapati, Nirav R. Patel, Kishan B Patel, Dushyant V. Patel, Ashish M. Kanhed
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:2498-2515
To confront a disease like Alzheimer's disease having complex pathogenesis, development of multitarget-directed ligands has emerged as a promising drug discovery approach. In our endeavor towards the development of multitarget-directed ligands for Al
Autor:
Kishan B Patel, Pallav M. Gandhi, Nirav R. Patel, Dharti B. Shah, Kirti V. Patel, Ashish M. Kanhed, Divya M. Teli, Bharat N Chaudhary, Sagar P. Patel, Navnit K Prajapati, Mange Ram Yadav, Dushyant V. Patel
Publikováno v:
ACS Chemical Neuroscience. 11:3557-3574
The inadequate clinical efficacy of the present anti-Alzheimer's disease (AD) drugs and their low impact on the progression of Alzheimer's disease in patients have revised the research focus from single targets to multitarget-directed ligands. A nove
Autor:
Mange Ram Yadav, Mahesh T. Chhabria, Ashish M. Kanhed, Divya M. Teli, Dushyant V. Patel, Nirav R. Patel
Publikováno v:
Molecular Diversity
The Corona virus Disease (COVID-19) is caused because of novel coronavirus (SARS-CoV-2) pathogen detected in China for the first time, and from there it spread across the globe creating a worldwide pandemic of severe respiratory complications. The vi
Autor:
Ashish M. Kanhed, Bharat N Chaudhary, Nirav R. Patel, Kirti V. Patel, Bhavik S. Shah, Dushyant V. Patel, Navnit K Prajapati, Divya M. Teli, Bhumi Gandhi, Kishan B Patel, Mange Ram Yadav
Publikováno v:
Journal of biomolecular structuredynamics. 40(20)
With the aim to combat a multi-faceted neurodegenerative Alzheimer's disease (AD), a series of carbazole-based semicarbazide and hydrazide derivatives were designed, synthesized and assessed for their cholinesterase (ChE) inhibitory, antioxidant and
Autor:
Anshuman Sinha, Navnit K Prajapati, Deep D. Kansara, Sarvangee B. Patel, Dharti B. Shah, Ashish M. Kanhed, Pragnesh N. Upadhyay, Kirti V. Patel, Prashant R. Murumkar, Mange Ram Yadav, Nirav R. Patel, Sagar P. Patel, Dushyant V. Patel, Annie R. Mecwan, Kishan B Patel
Publikováno v:
ACS Chemical Neuroscience. 10:3635-3661
The multifaceted nature of Alzheimer's disease (AD) demands treatment with multitarget-directed ligands (MTDLs) to confront the key pathological aberrations. A novel series of triazinoindole derivatives were designed and synthesized. In vitro studies
Autor:
Kirti V. Patel, Ashish M. Kanhed, Umesh R. Desai, Mange Ram Yadav, Daniel K. Afosah, Dushyant V. Patel, Sagar P. Patel, Rajshekhar Karpoormath, Nirav R. Patel
Publikováno v:
ChemistrySelect. 4:802-809
Publikováno v:
European Journal of Medicinal Chemistry. 121:671-698
Thrombosis is a leading cause of death in cardiovascular diseases such as myocardial infarction (MI), unstable angina and acute coronary syndrome (ACS) in the industrialized world. Venous thromboembolism is observed in about 1 million people every ye
Autor:
Prashant D. Joshi, Ashish M. Kanhed, Bharat N Chaudhary, Dushyant V. Patel, Kishan B Patel, Navnit K Prajapati, Sagar P. Patel, Divya M. Teli, Pallav M. Gandhi, Mange Ram Yadav, Kirti V. Patel, Nirav R. Patel
Publikováno v:
Bioorganic Chemistry. 101:103977
Molecules capable of engaging with multiple targets associated with pathological condition of Alzheimer's disease have proved to be potential anti-Alzheimer's agents. In our goal to develop multitarget-directed ligands for the treatment of Alzheimer
Autor:
Dushyant V. Patel, Nirav R. Patel
Azoles are a broad class of five-membered nitrogen containing heterocyclic ring systems that may contain other non-carbon atom(s) such as sulfur or oxygen. They are important heterocycles to develop novel therapeutic agents. Several nitrogen–sulfur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c28805c9a9275575f095a5c4f22a543
https://doi.org/10.1016/b978-0-08-102237-5.00008-0
https://doi.org/10.1016/b978-0-08-102237-5.00008-0