Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dushyant Kumar Srivastava"'
Autor:
Santanu Adhikary, Deepavali Chakravarti, Christopher Terranova, Isha Sengupta, Mayinuer Maitituoheti, Anirban Dasgupta, Dushyant Kumar Srivastava, Junsheng Ma, Ayush T. Raman, Emily Tarco, Aysegul A. Sahin, Roland Bassett, Fei Yang, Coya Tapia, Siddhartha Roy, Kunal Rai, Chandrima Das
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
H2B monoubiquitination is implicated in oncogenesis. Here, the authors show that UBR7 PHD finger is a H2BK120 monoubiquitin ligase that acts a tumour suppressor in breast cancer by suppressing gene expression for EMT, while promoting expression of CD
Externí odkaz:
https://doaj.org/article/d9e45b04af2247a480020df6e19b7638
Publikováno v:
Biochemical Journal. 478:1117-1136
Asf1 is a highly conserved histone chaperone that regulates tightly coupled nucleosome assembly/disassembly process. We observed that Plasmodium falciparum Asf1 (PfAsf1) is ubiquitously expressed in different stages of the life cycle of the parasite.
Autor:
Chandrima Das, Santanu Adhikary, Aysegul A. Sahin, Kunal Rai, Junsheng Ma, Fei Yang, Isha Sengupta, Sabita Roy, Anirban Dasgupta, Ayush T. Raman, Christopher Terranova, Deepavali Chakravarti, Mayinuer Maitituoheti, Roland L. Bassett, Dushyant Kumar Srivastava, Coya Tapia, Emily Tarco
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
The roles of Plant Homeodomain (PHD) fingers in catalysis of histone modifications are unknown. We demonstrated that the PHD finger of Ubiquitin Protein Ligase E3 Component N-Recognin7 (UBR7) harbors E3 ubiquitin ligase activity toward monoubiquitina
Autor:
Wasim Khan, Moitri Basu, Chandrima Das, Dushyant Kumar Srivastava, Siddhartha Roy, Isha Sengupta, Partha Chakrabarti
Publikováno v:
Biochemical Journal. 474:1919-1934
Enhanced migratory potential and invasiveness of cancer cells contribute crucially to cancer progression. These phenotypes are achieved by precise alteration of invasion-associated genes through local epigenetic modifications which are recognized by
Autor:
Dipak Dasgupta, Siddhartha Roy, Sulagna Sanyal, Dushyant Kumar Srivastava, Chandrima Das, Sabyasachi Sen
Transcription factor 19 (TCF19) has been reported as a type 1 diabetes–associated locus involved in maintenance of pancreatic β cells through a fine-tuned regulation of cell proliferation and apoptosis. TCF19 also exhibits genomic association with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4a7244f0afc7196573d9105160e83a
https://europepmc.org/articles/PMC5733577/
https://europepmc.org/articles/PMC5733577/
Autor:
Moitri Basu, Santanu Adhikary, Chandrima Das, Dushyant Kumar Srivastava, Sabyasachi Sen, Siddhartha Roy, Sulagna Sanyal, Isha Sengupta
Publikováno v:
The Journal of biological chemistry. 291(6)
ZMYND8 (zinc finger MYND (Myeloid, Nervy and DEAF-1)-type containing 8), a newly identified component of the transcriptional coregulator network, was found to interact with the Nucleosome Remodeling and Deacetylase (NuRD) complex. Previous reports ha