Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dushica Arsovska"'
Autor:
Vasil D'Ambrosio, Lea G. Hansen, Jie Zhang, Emil D. Jensen, Dushica Arsovska, Marcos Laloux, Tadas Jakočiūnas, Pernille Hjort, Davide De Lucrezia, Serena Marletta, Jay D. Keasling, Michael K. Jensen
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 2, Pp 657-663 (2022)
The synthetic biology toolkit for baker's yeast, Saccharomyces cerevisiae, includes extensive genome engineering toolkits and parts repositories. However, with the increasing complexity of engineering tasks and versatile applications of this model eu
Externí odkaz:
https://doaj.org/article/350328b816f64150aa8b75abe0b35547
Autor:
Vasil, D'Ambrosio, Lea G, Hansen, Jie, Zhang, Emil D, Jensen, Dushica, Arsovska, Marcos, Laloux, Tadas, Jakočiūnas, Pernille, Hjort, Davide, De Lucrezia, Serena, Marletta, Jay D, Keasling, Michael K, Jensen
Publikováno v:
Synthetic and systems biotechnology. 7(2)
The synthetic biology toolkit for baker's yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33576808ca80324cbc7230692cb35284
https://pubmed.ncbi.nlm.nih.gov/35224233
https://pubmed.ncbi.nlm.nih.gov/35224233
Autor:
Jie Zhang, Lea G. Hansen, Olga Gudich, Konrad Viehrig, Lærke M. M. Lassen, Lars Schrübbers, Khem B. Adhikari, Paulina Rubaszka, Elena Carrasquer-Alvarez, Ling Chen, Vasil D’Ambrosio, Beata Lehka, Ahmad K. Haidar, Saranya Nallapareddy, Konstantina Giannakou, Marcos Laloux, Dushica Arsovska, Marcus A. K. Jørgensen, Leanne Jade G. Chan, Mette Kristensen, Hanne B. Christensen, Suresh Sudarsan, Emily A. Stander, Edward Baidoo, Christopher J. Petzold, Tune Wulff, Sarah E. O’Connor, Vincent Courdavault, Michael K. Jensen, Jay D. Keasling
Publikováno v:
Nature
Zhang, J, Hansen, L G, Gudich, O, Viehrig, K, Lassen, L M M, Schrübbers, L, Adhikari, K B, Rubaszka, P, Carrasquer-Alvarez, E, Chen, L, D’Ambrosio, V, Lehka, B, Haidar, A K, Nallapareddy, S, Giannakou, K, Laloux, M, Arsovska, D, Jørgensen, M A K, Chan, L J G, Kristensen, M, Christensen, H B, Sudarsan, S, Stander, E A, Baidoo, E, Petzold, C J, Wulff, T, O’Connor, S E, Courdavault, V, Jensen, M K & Keasling, J D 2022, ' A microbial supply chain for production of the anti-cancer drug vinblastine ', Nature, vol. 609, no. 7926, pp. 341-347 . https://doi.org/10.1038/s41586-022-05157-3
Nature, vol 609, iss 7926
Zhang, J, Hansen, L G, Gudich, O, Viehrig, K, Lassen, L M M, Schrübbers, L, Adhikari, K B, Rubaszka, P, Carrasquer-Alvarez, E, Chen, L, D’Ambrosio, V, Lehka, B, Haidar, A K, Nallapareddy, S, Giannakou, K, Laloux, M, Arsovska, D, Jørgensen, M A K, Chan, L J G, Kristensen, M, Christensen, H B, Sudarsan, S, Stander, E A, Baidoo, E, Petzold, C J, Wulff, T, O’Connor, S E, Courdavault, V, Jensen, M K & Keasling, J D 2022, ' A microbial supply chain for production of the anti-cancer drug vinblastine ', Nature, vol. 609, no. 7926, pp. 341-347 . https://doi.org/10.1038/s41586-022-05157-3
Nature, vol 609, iss 7926
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine1. As MIAs are difficult to chemically synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bacac052957ae55ba7af120ea83ec4
https://pubmed.ncbi.nlm.nih.gov/36370691
https://pubmed.ncbi.nlm.nih.gov/36370691
Autor:
Markus J. Herrgård, Jay D. Keasling, Michael Krogh Jensen, Dushica Arsovska, Maitreya J. Dunham, Jie Zhang, Anne Sofie Lærke Hansen
Publikováno v:
ACS Synthetic Biology
Hansen, A S L, Dunham, M J, Arsovska, D, Zhang, J, Keasling, J D, Herrgard, M J & Jensen, M K 2020, ' Dietary Change Enables Robust Growth-Coupling of Heterologous Methyltransferase Activity in Yeast ', ACS Synthetic Biology, vol. 9, no. 12, pp. 3408-3415 . https://doi.org/10.1021/acssynbio.0c00348
Hansen, A S L, Dunham, M J, Arsovska, D, Zhang, J, Keasling, J D, Herrgard, M J & Jensen, M K 2020, ' Dietary Change Enables Robust Growth-Coupling of Heterologous Methyltransferase Activity in Yeast ', ACS Synthetic Biology, vol. 9, no. 12, pp. 3408-3415 . https://doi.org/10.1021/acssynbio.0c00348
Genetic modifications of living organisms and proteins are made possible by a catalogue of molecular and synthetic biology tools, yet proper screening assays for genetic variants of interest continue to lag behind. Synthetic growth-coupling (GC) of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c24a540b23f5787004244d66329004
Autor:
Justin D. Smith, Ling Ding, Raphael Ferreira, Florian David, Jay D. Keasling, Emil D. Jensen, Michael Krogh Jensen, Dushica Arsovska, Tadas Jakočiūnas, Jens Nielsen, Jie Zhang
Publikováno v:
Microbial cell factories, vol 16, iss 1
Jensen, ED; Ferreira, R; Jakočiunas, T; Arsovska, D; Zhang, J; Ding, L; et al.(2017). Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies. Microbial Cell Factories, 16(1). doi: 10.1186/s12934-017-0664-2. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/3b83k9m3
Damgaard Jensen, E, Ferreira, R, Jakociunas, T, Arsovska, D, Zhang, J, Ding, L, Smith, J D, David, F, Nielsen, J, Jensen, M K & Keasling, J D 2017, ' Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies ', Microbial Cell Factories, vol. 16, 46 . https://doi.org/10.1186/s12934-017-0664-2
Microbial Cell Factories
Jensen, ED; Ferreira, R; Jakočiunas, T; Arsovska, D; Zhang, J; Ding, L; et al.(2017). Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies. Microbial Cell Factories, 16(1). doi: 10.1186/s12934-017-0664-2. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/3b83k9m3
Damgaard Jensen, E, Ferreira, R, Jakociunas, T, Arsovska, D, Zhang, J, Ding, L, Smith, J D, David, F, Nielsen, J, Jensen, M K & Keasling, J D 2017, ' Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies ', Microbial Cell Factories, vol. 16, 46 . https://doi.org/10.1186/s12934-017-0664-2
Microbial Cell Factories
Background Transcriptional reprogramming is a fundamental process of living cells in order to adapt to environmental and endogenous cues. In order to allow flexible and timely control over gene expression without the interference of native gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5c91a2899b994e2e24ae9bf285c754
https://escholarship.org/uc/item/3b83k9m3
https://escholarship.org/uc/item/3b83k9m3
Autor:
Jensen, Emil, Ferreira, Raphael, JakoÄIĹŤnas, Tadas, Dushica Arsovska, Zhang, Jie, Ding, Ling, Smith, Justin, David, Florian, Nielsen, Jens, Jensen, Michael, Keasling, Jay
Additional file 3: Figure S2. Time-dependent regulation of reporter gene expression. Data were obtained with a BioLector from the same cultures as used in Supplementary Fig. S1. Indicated strains were targeted at pHMG1 or pOLE1 as in Fig. 1C with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0629d14d0920ccf15e451a8e2658d125
Autor:
Jie Zhang, Tim Snoek, Michael Krogh Jensen, Kanchana Rueksomtawin Kildegaard, Beata Joanna Lehka, Tobias Justus Goedecke, Irina Borodina, Jay D. Keasling, Mette Kristensen, Solvej Siedler, Mette L. Skjoedt, Arun S. Rajkumar, Dushica Arsovska, Michael Eichenberger
Publikováno v:
Nature chemical biology, vol 12, iss 11
Skjoedt, ML; Snoek, T; Kildegaard, KR; Arsovska, D; Eichenberger, M; Goedecke, TJ; et al.(2016). Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast. Nature Chemical Biology, 12(11), 951-958. doi: 10.1038/nchembio.2177. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6mm0t12g
Skjoedt, ML; Snoek, T; Kildegaard, KR; Arsovska, D; Eichenberger, M; Goedecke, TJ; et al.(2016). Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast. Nature Chemical Biology, 12(11), 951-958. doi: 10.1038/nchembio.2177. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6mm0t12g
© 2016 Nature America, Inc. All rights reserved. Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk and fine chemicals. Yet the screening of libraries of cellular designs to identify best-performing biocatalys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3525e99a5a59165529eb70848c627c
https://pubmed.ncbi.nlm.nih.gov/27755525
https://pubmed.ncbi.nlm.nih.gov/27755525
Autor:
Dushica Arsovska, Arun S. Rajkumar, Jay D. Keasling, Christian Bille Jendresen, Edith Angelica Rodriguez Prado, Tadas Jakociunas, Jie Zhang, Alex Toftgaard Nielsen, Mette Louise Skjødt, Irina Borodina, Michael Krogh Jensen
Publikováno v:
ACS synthetic biology. 4(11)
Homologous recombination (HR) in Saccharomyces cerevisiae has been harnessed for both plasmid construction and chromosomal integration of foreign DNA. Still, native HR machinery is not efficient enough for complex and marker-free genome engineering r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7434da82eb482f302f393bbc0a7b5f4
https://pubmed.ncbi.nlm.nih.gov/25781611
https://pubmed.ncbi.nlm.nih.gov/25781611
Autor:
Michael Krogh Jensen, Dushica Arsovska, Jay D. Keasling, Mette Kristensen, Guodong Liu, David Bergenholm, Arun S. Rajkumar, Jens Nielsen
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 44, iss 17
Rajkumar, A S, Liu, G, Bergenholm, D, Arsovska, D, Kristensen, M, Nielsen, J, Jensen, M K & Keasling, J 2016, ' Engineering of synthetic, stress-responsive yeast promoters ', Nucleic Acids Research, vol. 44, no. 17, e136 . https://doi.org/10.1093/nar/gkw553
Europe PubMed Central
Rajkumar, AS; Liu, G; Bergenholm, D; Arsovska, D; Kristensen, M; Nielsen, J; et al.(2016). Engineering of synthetic, stress-responsive yeast promoters. Nucleic Acids Research, 44(17). doi: 10.1093/nar/gkw553. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6f19p2cd
Nucleic acids research, vol 44, iss 17
Rajkumar, A S, Liu, G, Bergenholm, D, Arsovska, D, Kristensen, M, Nielsen, J, Jensen, M K & Keasling, J 2016, ' Engineering of synthetic, stress-responsive yeast promoters ', Nucleic Acids Research, vol. 44, no. 17, e136 . https://doi.org/10.1093/nar/gkw553
Europe PubMed Central
Rajkumar, AS; Liu, G; Bergenholm, D; Arsovska, D; Kristensen, M; Nielsen, J; et al.(2016). Engineering of synthetic, stress-responsive yeast promoters. Nucleic Acids Research, 44(17). doi: 10.1093/nar/gkw553. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6f19p2cd
© 2016 The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. Advances in synthetic biology and our understanding of the rules of promoter architecture have led to the development of diverse synthetic constitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21abcb5acaeb73b2e49eb42343d89420
http://europepmc.org/articles/PMC5041464
http://europepmc.org/articles/PMC5041464