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Modified live vaccine strains of porcine reproductive and respiratory syndrome virus cause immune system dysregulation similar to wild strains.

Autor: Stepanova K; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Toman M; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Sinkorova J; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Sinkora S; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Pfeiferova S; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Kupcova Skalnikova H; Laboratory of Applied Proteome Analyses and Research Center PIGMOD (Pig Models of Diseases), Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czechia.; Institute of Biochemistry and Experimental Oncology, First Faculty of Medicine, Charles University, Prague, Czechia., Abuhajiar S; Laboratory of Applied Proteome Analyses and Research Center PIGMOD (Pig Models of Diseases), Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czechia.; Department of Cell Biology, Faculty of Science, Charles University, Prague, Czechia., Moutelikova R; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Salat J; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Stepanova H; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Nechvatalova K; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Leva L; Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, Brno, Czechia., Hermanova P; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Kratochvilova M; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Dusankova B; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Sinkora M Jr; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Horak V; Laboratory of Applied Proteome Analyses and Research Center PIGMOD (Pig Models of Diseases), Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czechia., Hudcovic T; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia., Butler JE; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Sinkora M; Laboratory of Gnotobiology, Institute of Microbiology, Czech Academy of Sciences, Novy Hradek, Czechia.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jan 12; Vol. 14, pp. 1292381. Date of Electronic Publication: 2024 Jan 12 (Print Publication: 2023).