The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β.

Autor: Muhammad Saad Khilji, Danielle Verstappen, Tina Dahlby, Michala Cecilie Burstein Prause, Celina Pihl, Sophie Emilie Bresson, Tenna Holgersen Bryde, Phillip Alexander Keller Andersen, Kristian Klindt, Dusan Zivkovic, Marie-Pierre Bousquet-Dubouch, Björn Tyrberg, Thomas Mandrup-Poulsen, Michal Tomasz Marzec

Publikováno v: PLoS ONE, Vol 15, Iss 2, p e0222432 (2020)

A central and still open question regarding the pathogenesis of autoimmune diseases, such as type 1 diabetes, concerns the processes that underlie the generation of MHC-presented autoantigenic epitopes that become targets of autoimmune attack. Protea

Externí odkaz: https://doaj.org/article/d6b8ef2eb2994e95bba69f26b2ed0451

Follow-up dental examination a day after apicoectomy using the store-and-forward method

Autor: Djordje Mihailovic, Zoran Lazic, Dusan Zivkovic, Miloš Duka, Milan Zivkovic, Andrijana Karanovic, Meliha Sehalic, Milan Miladinović

Publikováno v: Vojnosanitetski Pregled, Vol 78, Iss 2, Pp 154-159 (2021)

Background/Aim. Although apicoectomy is performed routinely and yields excellent results, a close patient observation during the postoperative course is desirable in order to avoid possible complications. The aim of this study was to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028824cdedc0f941bfdc6fd0be4bab05
https://doi.org/10.2298/vsp190125045m

Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Ex-vivo Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells

Autor: Luc Garrigues, Florence Roux-Dalvai, Emmanuelle Mouton-Barbosa, Mathilde Beau, Luc Sensebé, Anne Gonzalez-de-Peredo, Dusan Zivkovic, Marie-Pierre Bousquet, Marie-Laure Renoud, Thomas Menneteau, Odile Burlet-Schiltz, Alexandre Stella, Bertrand Fabre, François Amalric, Isabelle Ader

Publikováno v: Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2019, 18 (4), pp.744-759. ⟨10.1074/mcp.RA118.000958⟩
Molecular & Cellular Proteomics : MCP

20S proteasomes are very heterogeneous protein complexes involved in many cellular processes. In the present study, we combined an MRM-based assay with the production and purification of entire SILAC labelled proteasome to monitor absolute quantities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c0fc14304749e1473488bb92fd5ba2
https://doi.org/10.1074/mcp.ra118.000958

Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins

Autor: Antonia Busse, Khadija Wahni, Vincent Stroobant, Marie-Pierre Bousquet, Joris Messens, Dusan Zivkovic, Benoît Guillaume, Joanna Abi Habib, Etienne De Plaen, Nathalie Vigneron, Benoît Van den Eynde

Publikováno v: Scientific Reports
Scientific reports, Vol. 10, no. 1, p. 15765 [1-17] (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.15765. ⟨10.1038/s41598-020-71550-5⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)

The proteasome is responsible for selective degradation of proteins. It exists in mammalian cells under four main subtypes, which differ by the combination of their catalytic subunits: the standard proteasome (β1–β2–β5), the immunoproteasome (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd19966e8a38281cdf5b334c794efe
https://doi.org/10.1038/s41598-020-71550-5

The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β

Autor: Sophie Emilie Bresson, Kristian Klindt, Thomas Mandrup-Poulsen, Phillip Alexander Keller Andersen, Marie-Pierre Bousquet-Dubouch, Celina Pihl, Tenna Holgersen Bryde, Tina Dahlby, Dusan Zivkovic, Muhammad Saad Khilji, Michala Prause, Michal Marzec, Danielle Verstappen, Björn Tyrberg

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0222432. ⟨10.1371/journal.pone.0222432⟩
Khilji, M S, Verstappen, D, Dahlby, T, Prause, M C B, Pihl, C, Bresson, S E, Bryde, T H, Andersen, P A K, Klindt, K, Zivkovic, D, Bousquet-Dubouch, M P, Tyrberg, B, Mandrup-Poulsen, T & Marzec, M T 2020, ' The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β ', PLoS ONE, vol. 15, no. 2, e0222432 . https://doi.org/10.1371/journal.pone.0222432
PLoS ONE, Vol 15, Iss 2, p e0222432 (2020)

International audience; A central and still open question regarding the pathogenesis of autoimmune diseases, such as type 1 diabetes, concerns the processes that underlie the generation of MHC-presented autoantigenic epitopes that become targets of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863383497e40a80987a92afde265bf34
https://hal-cnrs.archives-ouvertes.fr/hal-03018741/file/pone.0222432.pdf