Influence of Dextran Molecular Weight on the Physical Properties of Magnetic Nanoparticles for Hyperthermia and MRI Applications

Autor: Oliver Strbak, Iryna Antal, Iryna Khmara, Martina Koneracka, Martina Kubovcikova, Vlasta Zavisova, Matus Molcan, Alena Jurikova, Petra Hnilicova, Jan Gombos, Nina Kadasova, Dusan Dobrota

Publikováno v: Nanomaterials, Vol 10, Iss 12, p 2468 (2020)

Dextran-coated magnetic nanoparticles are promising biocompatible agents in various biomedical applications, including hyperthermia and magnetic resonance imaging (MRI). However, the influence of dextran molecular weight on the physical properties of

Externí odkaz: https://doaj.org/article/fe356bf9a1cb436aa0ea1b6a6767ccde

Role of homocysteine in the ischemic stroke nad development of ischemic tolerance

Autor: Jan Lehotsky, Barbara Tothova, Maria Kovalska, Dusan Dobrota, Anna Beňová, Dagmar Kalenska, Peter Kaplan

Publikováno v: Frontiers in Neuroscience, Vol 10 (2016)

Homocysteine (Hcy) is a toxic, sulfur-containing intermediate of methionine metabolism. Hyperhomocysteinemia (hHcy), as a consequence of impaired Hcy metabolism or defects in crucial co-factors that participate in its recycling, is assumed as an inde

Externí odkaz: https://doaj.org/article/1c683aab06454589bf751dfa53d369ff

Effect of Global Brain Ischemia on Amyloid Precursor Protein Metabolism and Expression of Amyloid-Degrading Enzymes in Rat Cortex: Role in Pathogenesis of Alzheimer’s Disease

Autor: Eva Babusikova, Natalia N. Nalivaeva, Anthony J. Turner, Dusan Dobrota

Publikováno v: Biochemistry (Moscow). 86:680-692

The incidence of Alzheimer's disease (AD) increases significantly following chronic stress and brain ischemia which, over the years, cause accumulation of toxic amyloid species and brain damage. The effects of global 15-min ischemia and 120-min reper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec86ecb554a8ae7f9e4897908acb86e4
https://doi.org/10.1134/s0006297921060067

The impact of external stress factors on hippocampus volume during antidepressant treatment

Autor: Ingrid Tonhajzerova, Dusan Dobrota, I Hrtanek, D Cesnekova, Igor Ondrejka, Marian Grendar, M. Bittsansky, M. Oppa, Ivan Farsky, P. Hutka, Kamil Zelenak

Publikováno v: The European Journal of Psychiatry. 35:92-98

Background and objectives Magnetic resonance imaging (MRI) studies suggest that depression is associated with volumetric hippocampal changes. Investigations of these structures during antidepressant therapy is therefore important, however, volumetric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49eaf0f344736091727e4cc18e6193c3
https://doi.org/10.1016/j.ejpsy.2020.12.004

Destruction of Lysozyme Amyloid Fibrils Induced by Magnetoferritin and Reconstructed Ferritin

Autor: Jan Gombos, Lucia Balejcikova, Peter Kopcansky, Marianna Batkova, Katarina Siposova, Jozef Kovac, Kristina Zolochevska, Ivo Safarik, Alica Lokajova, Vasil Garamus, Dusan Dobrota, Oliver Strbak

Publikováno v: Gombos, J.; Balejcikova, L.; Kopcansky, P.; Batkova, M.; Siposova, K.; Kovac, J.; Zolochevska, K.; Safarik, I.; Lokajova, A.; Garamus, V.M.; Dobrota, D.; Strbak, O.: Destruction of Lysozyme Amyloid Fibrils Induced by Magnetoferritin and Reconstructed Ferritin. In: International Journal of Molecular Sciences. Vol. 23 (2022) 22, 13926. (DOI: /10.3390/ijms232213926)
International Journal of Molecular Sciences
Volume 23
Issue 22
Pages: 13926

Neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), or systemic amyloidosis, are characterized by the specific protein transformation from the native state to stable insoluble deposits, e.g., amyloid plaques

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8015fd2d8853a5f9b90cedc9afb29f96
https://doi.org/10.3390/ijms232213926