Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dusan, Loderer"'
Autor:
Veronika Holubekova, Dusan Loderer, Marian Grendar, Peter Mikolajcik, Zuzana Kolkova, Eva Turyova, Eva Kudelova, Michal Kalman, Juraj Marcinek, Juraj Miklusica, Ludovit Laca, Zora Lasabova
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionColorectal cancer (CRC) is a heterogeneous disease caused by molecular changes, as driver mutations, gene methylations, etc., and influenced by tumor microenvironment (TME) pervaded with immune cells with both pro- and anti-tumor effects.
Externí odkaz:
https://doaj.org/article/7faa164c987947edada577494fd8400d
Autor:
Tomas Simurda, Rosanna Asselta, Jana Zolkova, Monika Brunclikova, Miroslava Dobrotova, Zuzana Kolkova, Dusan Loderer, Ingrid Skornova, Jan Hudecek, Zora Lasabova, Jan Stasko, Peter Kubisz
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2140 (2021)
Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative (dysfibrinogenemia and hypodysfibrinogenemia) disorders. The clinical phenotype is highly heterogene
Externí odkaz:
https://doaj.org/article/1b2962a9071f4dddb96c55543b50554b
Autor:
Zuzana Kolkova, Veronika Holubekova, Marian Grendar, Marcela Nachajova, Pavol Zubor, Terezia Pribulova, Dusan Loderer, Imrich Zigo, Kamil Biringer, Andrea Hornakova
Publikováno v:
Diagnostics, Vol 11, Iss 3, p 476 (2021)
MicroRNAs (miRNAs) are one of the important regulators of cellular functions fundamental for healthy pregnancy processes, including angiogenesis and differentiation of trophoblast cells, and their deregulation could be implicated in the pathogenesis
Externí odkaz:
https://doaj.org/article/12dcedb3a7f4437ea179c9a90b649e3a
Autor:
Tomas Simurda, Rui Vilar, Jana Zolkova, Eliska Ceznerova, Zuzana Kolkova, Dusan Loderer, Marguerite Neerman-Arbez, Alessandro Casini, Monika Brunclikova, Ingrid Skornova, Miroslava Dobrotova, Marian Grendar, Jan Stasko, Peter Kubisz
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 605 (2020)
Congenital hypofibrinogenemia is a rare bleeding disorder characterized by a proportional decrease of functional and antigenic fibrinogen levels. Hypofibrinogenemia can be considered the phenotypic expression of heterozygous loss of function mutation
Externí odkaz:
https://doaj.org/article/ba8b9f1b146c40b690bf7f4ed9c97dc4
Autor:
Ivan Kapralik, J Janik, Hugo Maurice Dumortier, Michael Bouvet, Dusan Brany, Dusan Loderer, Miroslav Pindura, Barbora Mitruskova, Henrieta Škovierová, Erika Halasova, Marian Grendar, Blazej Palkoci, Martin Kertys, Lukáš Plank, Mark A. Valasek, Juraj Mokry, Tomas Chromec, Martin Vojtko, Slavomíra Nováková, Michal Kalman, Juraj Marcinek, Sandra Mersakova, Roman Kycina, Laca L, Romana Zahumenska, Jan Strnadel
Publikováno v:
Neoplasma. 69:165-173
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive type of malignancy with one of the worst prognoses amongst any type of cancer. Surgery is applicable only to the limited number of patients with locally resectable tumors and currently re
Autor:
Barbora Váňová, Pavol Slavik, Alenka Líšková, Karla Scheerova, Dusan Loderer, Zora Lasabova, Ivana Kasubova, Marian Grendar, Anna Farkasova, Marek Samec, Katarína Janíková, Zuzana Dankova, Lukáš Plank
Publikováno v:
Neoplasma. 68:1107-1112
Ovarian cancer is the leading cause of mortality among all gynecological cancers in developed countries and its most common and most lethal type is the high-grade serous ovarian carcinoma (HGSC). At the molecular level, nearly half of all HGSCs exhib
Autor:
Martin Vojtko, Adam Svec, Zora Lasabova, Juraj Marcinek, Ivana Kasubova, Lukáš Plank, Alexander Johannes Wiederhold, Tatiana Burjanivova, Michal Kalman, J Janik, Peter Mikolajčík, Laca L, Marian Grendar, Vincent Lucansky, Eva Kudelova, Dusan Loderer
Publikováno v:
Neoplasma. 68:1331-1340
In colorectal cancer (CRC), clinically relevant biomarkers are known for genome-guided therapy that can be detected by both first and next generation methods. The aim of our work was to introduce a robust NGS assay that will be able to detect, in add
Autor:
Zora Lasabova, Jana Zolkova, Monika Brunclikova, Ingrid Skornova, Dusan Loderer, Peter Kubisz, Jan Stasko, Marian Grendar, Tomas Simurda, Zuzana Kolková, Miroslava Dobrotova
Publikováno v:
International Journal of Hematology. 111:795-802
Congenital dysfibrinogenemia (CD) is a rare disorder of hemostasis. The majority of cases are caused by heterozygous missense mutations in one of the three fibrinogen genes. Patients with CD may experience bleeding and thrombosis, but many are asympt
Autor:
Monika Brunclikova, Tomas Simurda, Jana Zolkova, Miroslava Sterankova, Ingrid Skornova, Miroslava Dobrotova, Zuzana Kolkova, Dusan Loderer, Marian Grendar, Jan Hudecek, Jan Stasko, Peter Kubisz
Publikováno v:
Journal of clinical medicine. 11(4)
Congenital fibrinogen disorders are diseases associated with a bleeding tendency; however, there are also reports of thrombotic events. Fibrinogen plays a role in the pathogenesis of thrombosis due to altered plasma concentrations or modifications to
Autor:
Jan Stasko, Rosanna Asselta, Zora Lasabova, Sonia Caccia, Dusan Loderer, Ingrid Skornova, Peter Kubisz, Jana Zolkova, Zuzana Snahnicanova, Tomas Simurda
Publikováno v:
Journal of Thrombosis and Thrombolysis. 50:233-236