Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Dusan, Hesek"'
Autor:
Siseth Martínez-Caballero, Céline Freton, Rafael Molina, Sergio G. Bartual, Virginie Gueguen-Chaignon, Chryslène Mercy, Federico Gago, Kiran V. Mahasenan, Inés G. Muñoz, Mijoon Lee, Dusan Hesek, Shahriar Mobashery, Juan A. Hermoso, Christophe Grangeasse
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112756- (2023)
Summary: Bacterial cell-wall hydrolases must be tightly regulated during bacterial cell division to prevent aberrant cell lysis and to allow final separation of viable daughter cells. In a multidisciplinary work, we disclose the molecular dialogue be
Externí odkaz:
https://doaj.org/article/d81c8fc5e2aa4f5d9ff7f86ec5f0dc25
Autor:
Siseth Martínez-Caballero, Kiran V. Mahasenan, Choon Kim, Rafael Molina, Rhona Feltzer, Mijoon Lee, Renee Bouley, Dusan Hesek, Jed F. Fisher, Inés G. Muñoz, Mayland Chang, Shahriar Mobashery, Juan A. Hermoso
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5392-5405 (2021)
The penicillin-binding proteins are the enzyme catalysts of the critical transpeptidation crosslinking polymerization reaction of bacterial peptidoglycan synthesis and the molecular targets of the penicillin antibiotics. Here, we report a combined cr
Externí odkaz:
https://doaj.org/article/0af59740be1241078a1417fa0b394874
Autor:
Kyungjin Min, Doo Ri An, Hye-Jin Yoon, Neha Rana, Ji Su Park, Jinshil Kim, Mijoon Lee, Dusan Hesek, Sangryeol Ryu, B. Moon Kim, Shahriar Mobashery, Se Won Suh, Hyung Ho Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Peptidoglycans (PG) define bacterial cell shapes. Here, the authors provide mechanistic insights into the peptidoglycan peptidase 3 (Pgp3) from the spiral shaped human pathogen Campylobacter jejuni by determining its crystal structure alone and in co
Externí odkaz:
https://doaj.org/article/13c1a77948d7413ba83fdcf089e8a278
Autor:
Martín Alcorlo, David A. Dik, Stefania De Benedetti, Kiran V. Mahasenan, Mijoon Lee, Teresa Domínguez-Gil, Dusan Hesek, Elena Lastochkin, Daniel López, Bill Boggess, Shahriar Mobashery, Juan A. Hermoso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
SPOR domains are present in bacterial proteins that recognize cell-wall peptidoglycan strands stripped of the peptide stems. Here, Alcorlo et al. show that, indeed, the presence of peptide stems abrogates binding to a SPOR domain, and provide insight
Externí odkaz:
https://doaj.org/article/120e67d6e4b84738995cb033a43e838a
Autor:
Thomas E. Smith, Mijoon Lee, Maria D. Person, Dusan Hesek, Shahriar Mobashery, Nancy A. Moran
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT During evolution, enzymes can undergo shifts in preferred substrates or in catalytic activities. An intriguing question is how enzyme function changes following horizontal gene transfer, especially for bacterial genes that have moved to anim
Externí odkaz:
https://doaj.org/article/6e00fba6110c413aad4670c24256bc40
Publikováno v:
ChemBioChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e13b3ff13e934b419b3154099a9bb72d
https://doi.org/10.1002/cbic.202300282
https://doi.org/10.1002/cbic.202300282
Autor:
Mijoon Lee, Shahriar Mobashery, Dusan Hesek, Focco van den Akker, Jacob Boorman, Elena Lastochkin, Ximin Zeng, Jun Lin, Snigdha A. Mathure, Vijay Kumar
Publikováno v:
Biochemistry. 60:1133-1144
The soluble lytic transglycosylase Cj0843c from Campylobacter jejuni breaks down cell-wall peptidoglycan (PG). Its nonhydrolytic activity sustains cell-wall remodeling and repair. We report herein our structure-function studies probing the substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::455a0d027b19aa8954e9241d16bcc51e
https://doi.org/10.1021/acs.biochem.1c00027
https://doi.org/10.1021/acs.biochem.1c00027
Autor:
Doo Ri An, Ha Na Im, Jun Young Jang, Hyoun Sook Kim, Jieun Kim, Hye Jin Yoon, Dusan Hesek, Mijoon Lee, Shahriar Mobashery, Soon-Jong Kim, Se Won Suh
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164243 (2016)
Colonization of the human gastric mucosa by Helicobacter pylori requires its high motility, which depends on the helical cell shape. In H. pylori, several genes (csd1, csd2, csd3/hdpA, ccmA, csd4, csd5, and csd6) play key roles in determining the cel
Externí odkaz:
https://doaj.org/article/8dfa46992680421299a4958c6cde9aef
Autor:
Julia Sanz-Aparicio, Mijoon Lee, Kiran V. Mahasenan, María T. Batuecas, Shahriar Mobashery, Choon Kim, Juan A. Hermoso, Jed F. Fisher, Neha Rana, Stefania De Benedetti, Dusan Hesek
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
8 pags., 5 figs.
BglX is a heretofore uncharacterized periplasmic glycoside hydrolase (GH) of the human pathogen Pseudomonas aeruginosa. X-ray analysis identifies it as a protein homodimer. The two active sites of the homodimer comprise catalyti
BglX is a heretofore uncharacterized periplasmic glycoside hydrolase (GH) of the human pathogen Pseudomonas aeruginosa. X-ray analysis identifies it as a protein homodimer. The two active sites of the homodimer comprise catalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fb3588b071701ca8769f50964297a2
https://doi.org/10.1021/acschembio.9b00754
https://doi.org/10.1021/acschembio.9b00754
Autor:
Daniel Lopez, Martín Alcorlo, Elena Lastochkin, Teresa Domínguez-Gil, Kiran V. Mahasenan, David A. Dik, Bill Boggess, Mijoon Lee, Shahriar Mobashery, Dusan Hesek, Stefania De Benedetti, Juan A. Hermoso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
13 pags., 9 figs. -- Open Access funded by Creative Commons Atribution Licence 4.0
SPOR domains are widely present in bacterial proteins that recognize cell-wall peptidoglycan strands stripped of the peptide stems. This type of peptidoglycan is
SPOR domains are widely present in bacterial proteins that recognize cell-wall peptidoglycan strands stripped of the peptide stems. This type of peptidoglycan is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077038b66204e85c0d604935c592b868
http://link.springer.com/article/10.1038/s41467-019-13354-4
http://link.springer.com/article/10.1038/s41467-019-13354-4