Do Xpert MTB/RIF Cycle Threshold Values Provide Information about Patient Delays for Tuberculosis Diagnosis?

Autor: Willy Ssengooba, Durval Respeito, Edson Mambuque, Silvia Blanco, Helder Bulo, Inacio Mandomando, Bouke C de Jong, Frank G Cobelens, Alberto L García-Basteiro

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162833 (2016)

INTRODUCTION:Early diagnosis and initiation to appropriate treatment is vital for tuberculosis (TB) control. The XpertMTB/RIF (Xpert) assay offers rapid TB diagnosis and quantitative estimation of bacterial burden through Cycle threshold (Ct) values.

Externí odkaz: https://doaj.org/article/18d97893479f40f3aaa3af154e30adae

Population-based surveillance of drug-resistant tuberculosis in Southern Mozambique based on whole genome sequencing

Autor: Carla Mariner-Llicer, Belén Saavedra Cervera, Edson Mambuque, Shilzia Munguambe, Neide Gomes, Luis Villamayor, Irving Cancino-Muñoz, Manuela Torres-Puente, Dinis Nguenha, Durval Respeito, Gustavo Tembe, Mariana G. López, Iñaki Comas, Alberto L. García-Basteiro

Mozambique is considered a high multidrug-resistant (MDR-TB) country by the World Health Organization (WHO) (3.7% new MDR-TB cases). The last national WHO survey was performed in 2008. Nowadays, South Africa and Eswatini are reporting an increase in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70cb547ba83cbe0ed211c3611f942c0b
https://doi.org/10.1101/2023.05.03.23289244

Mortality and risk of tuberculosis among people living with HIV in whom TB was initially ruled out

Autor: Luis A. Faife, Durval Respeito, Maxime Leroux-La Pierre, Elisa López-Varela, Dinis Nguenha, Tacilta Nhampossa, Juan Ignacio García, Manuel Fernández-Quevedo, Edson Mambuque, Belén Saavedra, Victor Guillermo Sequera, Helio Chiconela, Charfudin Sacoor, Faustino Vilanculo, Alberto L. García-Basteiro

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Dipòsit Digital de la UB
Universidad de Barcelona

Tuberculosis (TB) misdiagnosis remains a public health concern, especially among people living with HIV (PLHIV), given the high mortality associated with missed TB diagnoses. The main objective of this study was to describe the\xC2\xA0all-cause morta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04dc9ea67a7ffe281e28687e07e368c
https://doi.org/10.1038/s41598-020-71784-3

A Cytokine Pattern That Differentiates Preseroconversion From Postseroconversion Phases of Primary HIV Infection

Autor: Victor Urrea, Jorge Carrillo, Denise Naniche, Chenjerai Jairoce, Julià Blanco, Laura Fuente-Soro, Erica Parker, Inacio Mandomando, Durval Respeito, Lucía Pastor

Publikováno v: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

BACKGROUND: During acute HIV infection (AHI) HIV actively replicates but seroconversion has not yet occurred. Primary HIV infection (PHI) is characterized by a transient non-specific febrile illness, a massive inflammatory response and the progressiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f847a9539c9933f3bb77cd6b92eb451d
https://doi.org/10.1097/qai.0000000000001272

Typing and classification of non-tuberculous mycobacteria isolates

Autor: Harleen Grewal, Willy Ssengooba, Alberto L. García-Basteiro, Granger G. Sutton, Michele Tameris, Anthony Kiyimba, Ragini Macaden, Elisa Lopez, Thomas H. Clarke, Joanna Manoranjan, Lauren Brinkac, Durval Respeito

Publikováno v: F1000Research. 9:249

Background: There are a large and growing number of non-tuberculous mycobacteria (NTM) species that have been isolated, identified, and described in the literature, yet there are many clinical isolates which are not assignable to known species even w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c12ccba95e30c4615fdd489c7a73be30
https://doi.org/10.12688/f1000research.22620.2