A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma

Autor: Najjar, Devora, Rainbow, Josh, Timilsina, Sanjay, Jolly, Pawan, De Puig, Helena, Yafia, Mohamed, Durr, Nolan, Alter, Galit, Li, Jonathan, Yu, Xu, Walt, David, Paradiso, Joseph, Estrela, Pedro, Collins, James, Ingber, Donald E.

Publikováno v: Najjar, D, Rainbow, J, Timilsina, S, Jolly, P, De Puig, H, Yafia, M, Durr, N, Alter, G, Li, J, Yu, X, Walt, D, Paradiso, J, Estrela, P, Collins, J & Ingber, D E 2022, ' A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma ', Nature Biomedical Engineering, vol. 6, pp. 968-978 . https://doi.org/10.1101/2021.09.01.21262387, https://doi.org/10.1038/s41551-022-00919-w

Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who have Coronavi

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https://purehost.bath.ac.uk/ws/files/244265350/accepted_version.pdf

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A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma.

Autor: Najjar D; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA., Rainbow J; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio) and Department of Electronic and Electrical Engineering, University of Bath, Bath, UK., Sharma Timilsina S; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Jolly P; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., de Puig H; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Yafia M; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Durr N; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Sallum H; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Li JZ; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA., Yu XG; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA., Walt DR; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Paradiso JA; MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA., Estrela P; Centre for Biosensors, Bioelectronics and Biodevices (C3Bio) and Department of Electronic and Electrical Engineering, University of Bath, Bath, UK., Collins JJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. jimjc@mit.edu.; Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. jimjc@mit.edu.; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jimjc@mit.edu., Ingber DE; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. don.ingber@wyss.harvard.edu.; Harvard Medical School, Boston, MA, USA. don.ingber@wyss.harvard.edu.; Vascular Biology Program and Department of Surgery, Boston Children's Hospital, Boston, MA, USA. don.ingber@wyss.harvard.edu.; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA. don.ingber@wyss.harvard.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2022 Aug; Vol. 6 (8), pp. 968-978. Date of Electronic Publication: 2022 Aug 08.