Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Duronio, R J"'
Autor:
Duronio, R. J.
The duration of S phase in early embryos is often short, and then increases as development proceeds because of the appearance of late-replicating regions of the genome. In the April 1, 2012, issue of Genes & Development, Farrell and colleagues (pp. 7
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https://explore.openaire.eu/search/publication?articleId=doi_________::494005ec686568ffc18fc97a00f5d3eb
Autor:
Salzler, H. R., Dominski, Z., Marzluff, W. F., Burch, B. D., Duronio, R. J., Godfrey, A. C., Gasdaska, P. Y.
Metazoan replication-dependent histone mRNAs are the only nonpolyadenylated cellular mRNAs. Formation of the histone mRNA 3′ end requires the U7 snRNP, which contains Lsm10 and Lsm11, and FLASH, a processing factor that binds Lsm11. Here, we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7417d9939e3fbbb8ed2dc93da5795ec
Metazoan replication-dependent histone mRNAs are not polyadenylated, and instead terminate in a conserved stem–loop structure generated by an endonucleolytic cleavage of the pre-mRNA involving U7 snRNP. U7 snRNP contains two like-Sm proteins, Lsm10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed28cb1b65befd1e6c2db9d5d5794494
A great many cell types are necessary for the myriad capabilities of complex, multicellular organisms. One interesting aspect of this diversity of cell type is that many cells in diploid organisms are polyploid. This is called endopolyploidy and aris
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https://explore.openaire.eu/search/publication?articleId=doi_________::22e074a857669891d52b635930f76eee
Tuberous sclerosis (TSC) is an autosomal dominant disease characterized by hamartoma formation in various organs and is caused by mutations targeting either the TSC1 or TSC2 genes. TSC1 and TSC2 proteins form a functionally interdependent dimeric com
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https://explore.openaire.eu/search/publication?articleId=doi_________::688a76399a860297581802bdfcdf81cf
The DnaQ-H family exonuclease Snipper (Snp) is a 33-kDa Drosophila melanogaster homolog of 3′hExo and ERI-1, exoribonucleases implicated in the degradation of histone mRNA in mammals and in the negative regulation of RNA interference (RNAi) in Caen
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https://explore.openaire.eu/search/publication?articleId=doi_________::b22c43be9eb9e27d597dcc48d35872be
Individual members of the E2F/DP protein family control cell cycle progression by acting predominantly as an activator or repressor of transcription. In Drosophila melanogaster the E2f1, E2f2, Dp, and Rbf1 genes all contribute to replication control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5937dba2a6a551a59cddf65a17afe009
Autor:
Dominski, Z., Duronio, R. J., Raska, C. S., Borchers, C. H., Marzluff, W. F., Santiago, C., Yang, X.-c.
Synthetic pre-mRNAs containing the processing signals encoded by Drosophila melanogaster histone genes undergo efficient and faithful endonucleolytic cleavage in nuclear extracts prepared from Drosophila cultured cells and 0- to 13-h-old embryos. Bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61f367f25aedffc7b7713ea8cf5828d1
In metazoans, the 3′ end of histone mRNA is not polyadenylated but instead ends with a stem-loop structure that is required for cell cycle-regulated expression. The sequence of the stem-loop in the Drosophila melanogaster histone H2b, H3, and H4 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8283466a40d84bd7f9bcae83b285d039
Drosophila contains two members of the E2F transcription factor family (E2f and E2f2), which controls the expression of genes that regulate the G1-S transition of the cell cycle. Previous genetic analyses have indicated that E2f is an essential gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c80c926016643b400bd416b66d56986