Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Durigutto, P"'
Autor:
Davide Busato, Sara Capolla, Paolo Durigutto, Monica Mossenta, Sara Bozzer, Daniele Sblattero, Paolo Macor, Michele Dal Bo, Giuseppe Toffoli
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with a very low survival rate at 5 years. The use of chemotherapeutic agents results in only modest prolongation of survival and is generally associated
Externí odkaz:
https://doaj.org/article/da4516817faf461f9882e4337173d4b5
Autor:
Paolo Macor, Paolo Durigutto, Monica Argenziano, Kate Smith-Jackson, Sara Capolla, Valeria Di Leonardo, Kevin Marchbank, Valerio Stefano Tolva, Fabrizio Semeraro, Concetta T. Ammollo, Mario Colucci, Roberta Cavalli, Pierluigi Meroni, Francesco Tedesco
Publikováno v:
Haematologica, Vol 108, Iss 7 (2022)
β2-glycoprotein I (β2-GPI) is a serum protein widely recognized as the main target of antibodies present in patients with antiphospholipid syndrome (APS). β2-GPI binds to activated endothelial cells, platelets and leukocytes, key players in thromb
Externí odkaz:
https://doaj.org/article/98d50d9c03c845fe962d09eab9d61bcc
Akademický článek
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Autor:
Paolo Macor, Paolo Durigutto, Alessandro Mangogna, Rossana Bussani, Luca De Maso, Stefano D’Errico, Martina Zanon, Nicola Pozzi, Pier Luigi Meroni, Francesco Tedesco
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1003 (2021)
Increased levels of circulating complement activation products have been reported in COVID-19 patients, but only limited information is available on complement involvement at the tissue level. The mechanisms and pathways of local complement activatio
Externí odkaz:
https://doaj.org/article/53ef733e8653497a9b602f7e544d58e9
Autor:
Paolo Durigutto, Claudia Grossi, Maria Orietta Borghi, Paolo Macor, Francesca Pregnolato, Elena Raschi, Michael P. Myers, Philip G. de Groot, Pier Luigi Meroni, Francesco Tedesco
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of β2glycoproteinI in terms of risk of thrombosis and pregnancy complications in patients with antiphospholipid syndrome. To obtain direct evidenc
Externí odkaz:
https://doaj.org/article/49cd3e6bfacb4bf988f49f0dfaf1da92
Autor:
Roberta Bulla, Claudio Tripodo, Damiano Rami, Guang Sheng Ling, Chiara Agostinis, Carla Guarnotta, Sonia Zorzet, Paolo Durigutto, Marina Botto, Francesco Tedesco
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.
Externí odkaz:
https://doaj.org/article/2b1fca59ed134efe8e0682260b30cecc
Autor:
Paolo Durigutto, Daniele Sblattero, Stefania Biffi, Luca De Maso, Chiara Garrovo, Gabriele Baj, Federico Colombo, Fabio Fischetti, Antonio F. Di Naro, Francesco Tedesco, Paolo Macor
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Complement activation is largely implicated in the pathogenesis of several clinical conditions and its therapeutic neutralization has proven effective in preventing tissue and organ damage. A problem that still needs to be solved in the therapeutic c
Externí odkaz:
https://doaj.org/article/97ab0481344745119af4128c212913b0
Autor:
Bulla, R., De Seta, F., Radillo, O., Agostinis, C., Durigutto, P., Pellis, V., De Santo, D., Crovella, S., Tedesco, F.
Publikováno v:
In Molecular Immunology July 2010
Akademický článek
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Autor:
Paolo Durigutto, Paolo Macor, Federica Ziller, Luca De Maso, Fabio Fischetti, Roberto Marzari, Daniele Sblattero, Francesco Tedesco
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58696 (2013)
Treatment of patients suffering from chronic diseases such as rheumatoid arthritis with recombinant antibodies is time consuming and fairly expensive and can be associated with side effects due to generalized depletion of the target molecule. We have
Externí odkaz:
https://doaj.org/article/4d85e3b091414bb6ac267dce6405d6db