Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Durga Bhavani Dandamudi"'
Autor:
Raquel Duque Nascimento Arifa, Durga Bhavani Dandamudi, Michael L. Dustin, Viveka Mayya, Juan J. Lafaille, David A. Blair
Granzyme B mRNA is expressed in primed CD8 T cells within 12 hours, but the consequences of this for the immune response are unknown. We observed that substantial portion of the naïve CD8 T cell repertoire expressed granzyme B and became pre-mitotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150f6474944738fc421e4d867c721b72
Autor:
Arlene H. Sharpe, Ian A. Blair, William J. Murphy, David H. Munn, Roddy S. O’Connor, Jonathan S. Serody, Catarina Sacristán, Govindarajan Thangavelu, Caleph B. Wilson, Gordon J. Freeman, Jan M. Pawlicki, Michael C. Milone, Bruce R. Blazar, Scott B. Lovitch, Asim Saha, Durga Bhavani Dandamudi, Rocio Foncea, James L. Riley, Laurence A. Turka, Kazutoshi Aoyama, Scott N. Furlan, Parvathi Ranganathan, Patricia A. Taylor, Brian T. Fife, David A. Bernlohr, Angela Panoskaltsis-Mortari, Benjamin G. Vincent, Leslie S. Kean, Joel S. Burrill, Lili Guo, Steven M. Devine, Victor Tkachev, Michael L. Dustin, Jeffrey S. Miller, Nathaniel W. Snyder
Publikováno v:
The Journal of clinical investigation, vol 126, iss 7
Programmed death ligand-1 (PD-L1) interaction with PD-1 induces T cell exhaustion and is a therapeutic target to enhance immune responses against cancer and chronic infections. In murine bone marrow transplant models, PD-L1 expression on host target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ce613879b38d9eef026f324fc7ded4
https://escholarship.org/uc/item/4tn003bd
https://escholarship.org/uc/item/4tn003bd
Autor:
Saurabh Mehandru, Paula M Longhi, Durga Bhavani Dandamudi, Ralph M. Steinman, Cheolho Cheong, Angela Teixeira, Darren Ruane, Elina Shrestha, Luke Brane, Austin R. Pantel, Leonia Bozzacco
Publikováno v:
European Journal of Immunology. 42:101-109
Protein-based vaccines offer safety and cost advantages but require adjuvants to induce immunity. Here we examined the adjuvant capacity of glucopyranosyl lipid A (GLA), a new synthetic non-toxic analogue of lipopolysaccharide. In mice, in comparison
Autor:
Durga Bhavani Dandamudi, Saurabh Mehandru, Goo Taeg Oh, Chae Gyu Park, In Hyuk Jung, Ralph M. Steinman, Jae-Hoon Choi, Ji Young Yoo, Cheolho Cheong, Klara Velinzon, Anthony Rodriguez
Publikováno v:
Immunity. 35(5):819-831
Early events in atherosclerosis occur in the aortic intima and involve monocytes that become macrophages. We looked for these cells in the steady state adult mouse aorta, and surprisingly, we found a dominance of dendritic cells (DCs) in the intima.
Autor:
Cheolho Cheong, Tibor Keler, Durga Bhavani Dandamudi, Godwin Nchinda, Sung Ho Park, Yoonkyung Do, Li Zhen He, Chae Gyu Park, Jae-Hoon Choi, Christine Trumpfheller, Han Woong Lee, Elina Shrestha, Maggi Pack, Ralph M. Steinman, Laura Vitale, Leonia Bozzacco
Publikováno v:
Blood. 116:3828-3838
Protein vaccines for T-cell immunity are not being prioritized because of poor immunogenicity. To overcome this hurdle, proteins are being targeted to maturing dendritic cells (DCs) within monoclonal antibodies (mAbs) to DC receptors. To extend the c
Autor:
Ines Matos, Jessy A. Makeyeva, Elina Shrestha, Jae-Hoon Choi, Chae Gyu Park, Joseph D. Schauer, Durga Bhavani Dandamudi, Ralph M. Steinman, Xiaojun Li, Pingwei Li, Cheolho Cheong
Publikováno v:
Journal of Immunological Methods. 360:66-75
Mouse DC-SIGN CD209a is a type II transmembrane protein, one of a family of C-type lectin genes syntenic and homologous to human DC-SIGN. Current anti-mouse DC-SIGN monoclonal antibodies (MAbs) are unable to react with DC-SIGN in acetone fixed cells,
Autor:
Anthony Rodriguez, M. Paula Longhi, Chae Gyu Park, Ralph M. Steinman, Hyein Koh, Durga Bhavani Dandamudi, Kate L. Jeffrey, Courtney Kluger, Elina Shrestha, Jae-Hoon Choi, Godwin Nchinda, Cheolho Cheong, Juliana Idoyaga, Klara Velinzon, Maggi Pack, Robert M. Anthony, Ines Matos
Publikováno v:
Cell. 143(3)
SummaryDendritic cells (DCs), critical antigen-presenting cells for immune control, normally derive from bone marrow precursors distinct from monocytes. It is not yet established if the large reservoir of monocytes can develop into cells with critica
Autor:
Caleph B. Wilson, Jonathan S. Serody, David A. Bernlohr, Angela Panoskaltsis-Mortari, Scott B. Lovitch, Arlene H. Sharpe, Asim Saha, Patricia A. Taylor, Gordon J. Freeman, Govindarajan Thangavelu, Lili Guo, Kazutoshi Aoyama, James L. Riley, Bruce R. Blazar, William J. Murphy, Roddy S. O’Connor, David H. Munn, Ian A. Blair, Joel S. Burrill, Leslie S. Kean, Brian T. Fife, Jeffrey S. Miller, Nathaniel W. Snyder, Catarina Sacristán, Laurence A. Turka, Michael L. Dustin, Durga Bhavani Dandamudi, Rocio Foncea, Benjamin G. Vincent, Scott N. Furlan, Michael C. Milone
Publikováno v:
Blood. 126:147-147
The PD-1/PD-L1 pathway plays an important role in regulation of alloimmune responses and in induction and maintenance of peripheral tolerance. Because GVHD is driven by donor T cells and PD-L1 expression can be markedly elevated on T cells during act