Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas.

Autor: Burger BT; Genus plc Research and Development, DeForest, Wisconsin, USA., Beaton BP; Genus plc Research and Development, DeForest, Wisconsin, USA., Campbell MA; Genus plc Research and Development, DeForest, Wisconsin, USA., Brett BT; Genus plc Research and Development, DeForest, Wisconsin, USA., Rohrer MS; Genus plc Research and Development, DeForest, Wisconsin, USA., Plummer S; Genus plc Research and Development, DeForest, Wisconsin, USA., Barnes D; Genus plc Research and Development, DeForest, Wisconsin, USA., Jiang K; Genus plc Research and Development, DeForest, Wisconsin, USA., Naswa S; Genus plc Research and Development, DeForest, Wisconsin, USA., Lange J; Genus plc Research and Development, DeForest, Wisconsin, USA., Ott A; Genus plc Research and Development, DeForest, Wisconsin, USA., Alger E; Genus plc Research and Development, DeForest, Wisconsin, USA., Rincon G; Genus plc Research and Development, DeForest, Wisconsin, USA., Rounsley S; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Inari Agriculture, West Lafayette, IN, USA., Betthauser J; Genus plc Research and Development, DeForest, Wisconsin, USA., Mtango NR; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Colossal Biosciences, Dallas, TX, USA., Benne JA; Genus plc Research and Development, DeForest, Wisconsin, USA., Hammerand J; Genus plc Research and Development, DeForest, Wisconsin, USA., Durfee CJ; Genus plc Research and Development, DeForest, Wisconsin, USA., Rotolo ML; PIC, Hendersonville, Tennessee, USA.; Current address: National Pork Board, Des Moines, IA, USA., Cameron P; Caribou Biosciences, Berkeley, California, USA.; Current address: Profluent Bio, Berkeley, CA, USA., Lied AM; Caribou Biosciences, Berkeley, California, USA., Irby MJ; Caribou Biosciences, Berkeley, California, USA.; Current address: Prime Medicine, Cambridge, MA, USA., Nyer DB; Caribou Biosciences, Berkeley, California, USA.; Current address: Clade Therapeutics, Boston, MA, USA., Fuller CK; Caribou Biosciences, Berkeley, California, USA., Gradia S; Caribou Biosciences, Berkeley, California, USA., Kanner SB; Caribou Biosciences, Berkeley, California, USA., Park KE; RenOVAte Biosciences, Reisterstown, Maryland, USA., Waters J; RenOVAte Biosciences, Reisterstown, Maryland, USA., Simpson S; RenOVAte Biosciences, Reisterstown, Maryland, USA., Telugu BP; RenOVAte Biosciences, Reisterstown, Maryland, USA., Salgado BC; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Brandariz-Nuñez A; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Rowland RRR; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Culbertson M; PIC, Hendersonville, Tennessee, USA., Rice E; Genus plc Research and Development, DeForest, Wisconsin, USA., Cigan AM; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Cobb-Vantress, Siloam Springs, AR, USA.

Publikováno v: The CRISPR journal [CRISPR J] 2024 Feb; Vol. 7 (1), pp. 12-28.

A DNA Regulatory Element Haplotype at Zinc Finger Genes Is Associated with Host Resilience to Small Ruminant Lentivirus in Two Sheep Populations.

Autor: Massa AT; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA., Mousel MR; Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA.; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99163, USA., Durfee CJ; Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA., Herndon MK; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA., Hemmerling KM; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99163, USA., Taylor JB; Range Sheep Production Efficiency Research, Agricultural Research Service, United States Department of Agriculture, Dubois, ID 83423, USA., Neibergs HL; Department of Animal Science, Washington State University, Pullman, WA 99163, USA.; Center for Reproductive Biology, Washington State University, Pullman, WA 99163, USA., White SN; Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, WA 99163, USA.; Center for Reproductive Biology, Washington State University, Pullman, WA 99163, USA.

Publikováno v: Animals : an open access journal from MDPI [Animals (Basel)] 2021 Jun 26; Vol. 11 (7). Date of Electronic Publication: 2021 Jun 26.