Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Durand-Réville TF"'
1
Akademický článek
Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases.
Autor: Durand-Réville TF; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Comita-Prevoir J; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Zhang J; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Wu X; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., May-Dracka TL; Infection Discovery, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Romero JAC; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Wu F; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Chen A; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Shapiro AB; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Carter NM; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., McLeod SM; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Giacobbe RA; Infection Discovery, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Verheijen JC; Infection Discovery, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Lahiri SD; Infection Discovery, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Sacco MD; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Boulevard, Tampa, Florida 33612, United States., Chen Y; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Boulevard, Tampa, Florida 33612, United States., O'Donnell JP; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Miller AA; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Mueller JP; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Tommasi RA; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Nov 12; Vol. 63 (21), pp. 12511-12525. Date of Electronic Publication: 2020 Jul 24.
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2
Akademický článek
Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin.
Autor: Iyer R; Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States., Moussa SH; Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States., Durand-Réville TF; Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States., Tommasi R; Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States., Miller A; Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.
Publikováno v: ACS infectious diseases [ACS Infect Dis] 2018 Mar 09; Vol. 4 (3), pp. 373-381. Date of Electronic Publication: 2017 Dec 26.
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3
Akademický článek
ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
Autor: Durand-Réville TF; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Guler S; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Comita-Prevoir J; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Chen B; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Bifulco N; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Huynh H; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Lahiri S; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Shapiro AB; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., McLeod SM; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Carter NM; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Moussa SH; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Velez-Vega C; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Olivier NB; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., McLaughlin R; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Gao N; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Thresher J; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Palmer T; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Andrews B; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Giacobbe RA; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Newman JV; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Ehmann DE; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., de Jonge B; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., O'Donnell J; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Mueller JP; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Tommasi RA; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA., Miller AA; Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA.
Publikováno v: Nature microbiology [Nat Microbiol] 2017 Jun 30; Vol. 2, pp. 17104. Date of Electronic Publication: 2017 Jun 30.
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4
Akademický článek
SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
Autor: Murphy-Benenato KE; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Dangel B; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Davis HE; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Durand-Réville TF; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Ferguson AD; Structure and Biophysics, and Reagents & Assay Development, Discovery Sciences, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Gao N; Structure and Biophysics, and Reagents & Assay Development, Discovery Sciences, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Jahić H; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Mueller JP; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Manyak EL; Structure and Biophysics, and Reagents & Assay Development, Discovery Sciences, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Quiroga O; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Rooney M; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Sha L; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Sylvester M; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Wu F; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Zambrowski M; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Zhao SX; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2015 Mar 22; Vol. 6 (5), pp. 537-42. Date of Electronic Publication: 2015 Mar 22 (Print Publication: 2015).
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5
Akademický článek
Discovery of efficacious Pseudomonas aeruginosa-targeted siderophore-conjugated monocarbams by application of a semi-mechanistic pharmacokinetic/pharmacodynamic model.
Autor: Murphy-Benenato KE; Infection Innovative Medicines and ‡Discovery Sciences, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Bhagunde PR, Chen A, Davis HE, Durand-Réville TF, Ehmann DE, Galullo V, Harris JJ, Hatoum-Mokdad H, Jahić H, Kim A, Manjunatha MR, Manyak EL, Mueller J, Patey S, Quiroga O, Rooney M, Sha L, Shapiro AB, Sylvester M, Tan B, Tsai AS, Uria-Nickelsen M, Wu Y, Zambrowski M, Zhao SX
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2015 Mar 12; Vol. 58 (5), pp. 2195-205. Date of Electronic Publication: 2015 Mar 03.
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6
Akademický článek
Enantioselective Synthesis and Profiling of Two Novel Diazabicyclooctanone β-Lactamase Inhibitors.
Autor: Xiong H; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Chen B; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Durand-Réville TF; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Joubran C; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Alelyunas YW; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Wu D; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Huynh H; Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2014 Aug 12; Vol. 5 (10), pp. 1143-7. Date of Electronic Publication: 2014 Aug 12 (Print Publication: 2014).
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7
Akademický článek
Kinetics of avibactam inhibition against Class A, C, and D β-lactamases.
Autor: Ehmann DE; From the Infection Innovative Medicines Unit and the Discovery Sciences Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts 02451., Jahic H, Ross PL, Gu RF, Hu J, Durand-Réville TF, Lahiri S, Thresher J, Livchak S, Gao N, Palmer T, Walkup GK, Fisher SL
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2013 Sep 27; Vol. 288 (39), pp. 27960-71. Date of Electronic Publication: 2013 Aug 02.
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Plný text Recenzováno Digitální knihovna AV ČR
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