Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Dupic, Thomas"'
Autor:
Abbate, Maria Francesca, Dupic, Thomas, Vigne, Emmanuelle, Shahsavarian, Melody A., Walczak, Aleksandra M., Mora, Thierry
B cell receptors (BCRs) play a crucial role in recognizing and fighting foreign antigens. High-throughput sequencing enables in-depth sampling of the BCRs repertoire after immunization. However, only a minor fraction of BCRs actively participate in a
Externí odkaz:
http://arxiv.org/abs/2312.13465
B-cell repertoires are characterized by a diverse set of receptors of distinct specificities generated through two processes of somatic diversification: V(D)J recombination and somatic hypermutations. B cell clonal families stem from the same V(D)J r
Externí odkaz:
http://arxiv.org/abs/2212.11997
Autor:
Dupic, Thomas, Koraichi, Meriem Bensouda, Minervina, Anastasia, Pogorelyy, Mikhail, Mora, Thierry, Walczak, Aleksandra M.
Publikováno v:
PLoS Genetics 17 (1) e1009301 (2021)
Immune repertoires provide a unique fingerprint reflecting the immune history of individuals, with potential applications in precision medicine. However, the question of how personal that information is and how it can be used to identify individuals
Externí odkaz:
http://arxiv.org/abs/2006.13530
Autor:
Sethna, Zachary, Isacchini, Giulio, Dupic, Thomas, Mora, Thierry, Walczak, Aleksandra M., Elhanati, Yuval
Publikováno v:
PLoS Computational Biology 16(12) e1008394 (2020)
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically stochastic steps: random receptor generation by VDJ recombination, and selection based on the recognition of random self-peptides presented on the ma
Externí odkaz:
http://arxiv.org/abs/2001.02843
The Fully-Packed Loop (FPL) model on the honeycomb lattice is a critical model of non-intersecting polygons covering the full lattice, and was introduced by Reshetikhin in 1991. Using the two-component Coulomb-Gas approach of Kondev, de Gier and Nien
Externí odkaz:
http://arxiv.org/abs/1901.02086
Publikováno v:
In Trends in Immunology May 2023 44(5):384-396
We consider the two-dimensional $\mathfrak{sl}_n$ quantum Toda field theory with an imaginary background charge. This conformal field theory has a higher spin symmetry ($W_n$ algebra), a central charge $c \leq n-1$ and a continuous spectrum. Using th
Externí odkaz:
http://arxiv.org/abs/1809.05568
Publikováno v:
PLoS Comp. Biol. 15(3): e1006874 (2019)
The T-cell (TCR) repertoire relies on the diversity of receptors composed of two chains, called $\alpha$ and $\beta$, to recognize pathogens. Using results of high throughput sequencing and computational chain-pairing experiments of human TCR reperto
Externí odkaz:
http://arxiv.org/abs/1806.11030
Publikováno v:
SciPost Phys. 4, 031 (2018)
We present a new method to compute R\'enyi entropies in one-dimensional critical systems. The null-vector conditions on the twist fields in the cyclic orbifold allow us to derive a differential equation for their correlation functions. The latter are
Externí odkaz:
http://arxiv.org/abs/1709.09270
The fully packed loop (FPL) model is a statistical model related to the integrable $U_q(\hat{\mathfrak{sl}}_3)$ vertex model. In this paper we study the continuum limit of the FPL. With the appropriate weight of non-contractible loops, we give eviden
Externí odkaz:
http://arxiv.org/abs/1606.05376