Optimization of the extraction process and metabonomics analysis of uric acid-reducing active substances from Gymnadenia R.Br. and its protective effect on hyperuricemia zebrafish

Autor: Tianrong Chen, Duoji Pubu, Wenhui Zhang, Shengya Meng, Cuicui Yu, Xiaoqing Yin, Jiale Liu, Yuhong Zhang

Publikováno v: Frontiers in Nutrition, Vol 9 (2022)

BackgroundAs Gymnadenia R.Br. (Gym) has an obvious uric acid-lowering effect, but its specific bioactive substances and mechanism are still unclear. The key metabolites and pathways used by Gym to reduce uric acid (UA) were identify.MethodsAn optimiz

Externí odkaz: https://doaj.org/article/22034c3ce2d94cca9bd7269af562059e

Optimization of Ultrasound-Assisted Extraction, HPLC and UHPLC-ESI-Q-TOF-MS/MS Analysis of Main Macamides and Macaenes from Maca (Cultivars of Lepidium meyenii Walp)

Autor: Li-Rong Chen, Zhen Yang, Bin Chen, Si-Ping Jiang, Xiao-Jie Gong, Ke-Ke Li, Shu-Xiao Chen, Duoji Pubu, Chao Ma

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 12; Pages: 2196
Molecules, Vol 22, Iss 12, p 2196 (2017)

Ultrasound-assisted extraction (UAE), using petroleum ether as the solvent, was systematically applied to extract main macamides and macaenes from Maca hypocotyls. Extraction yield was related with four variables, including ratio of solution to solid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eaa4cc619c6c1804f45f3085ce438eb
http://europepmc.org/articles/PMC6149678