Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dunstan ML"'
Autor:
Jun, G, Ibrahim-Verbaas, CA, Vronskaya, M, Lambert, J-C, Chung, J, Naj, AC, Kunkle, BW, Wang, L-S, Bis, JC, Bellenguez, C, Harold, D, Lunetta, KL, Destefano, AL, Grenier-Boley, B, Sims, R, Beecham, GW, Smith, AV, Chouraki, V, Hamilton-Nelson, KL, Ikram, MA, Fievet, N, Denning, N, Martin, ER, Schmidt, H, Kamatani, Y, Dunstan, ML, Valladares, O, Laza, AR, Zelenika, D, Ramirez, A, Foroud, TM, Choi, S-H, Boland, A, Becker, T, Kukull, WA, Van Der Lee, SJ, Pasquier, F, Cruchaga, C, Beekly, D, Fitzpatrick, AL, Hanon, O, Gill, M, Barber, R, Gudnason, V, Campion, D, Love, S, Bennett, DA, Amin, N, Berr, C, Tsolaki, Magda, Buxbaum, JD, Lopez, OL, Deramecourt, V, Fox, NC, Cantwell, LB, Tárraga, L, Dufouil, C, Hardy, J, Crane, PK, Eiriksdottir, G, Hannequin, D, Clarke, R, Evans, D, Mosley, TH, Letenneur, L, Brayne, C, Maier, W, De Jager, P, Emilsson, V, Dartigues, J-F, Hampel, H, Kamboh, MI, De Bruijn, RFAG, Tzourio, C, Pastor, P, Larson, EB, Rotter, JI, O'Donovan, MC, Montine, TJ, Nalls, MA, Mead, S, Reiman, EM, Jonsson, PV, Holmes, C, St George-Hyslop, PH, Boada, M, Passmore, P, Wendland, Schmidt, R, Morgan, K, Winslow, AR, Powell, JF, Carasquillo, M, Younkin, SG, Jakobsdóttir, J, Kauwe, JSK, Wilhelmsen, KC, Rujescu, D, Nöthen, MM, Hofman, A, Jones, L, IGAP Consortium, Haines, JL, Psaty, BM, Van Broeckhoven, C, Holmans, P, Launer, LJ, Mayeux, R, Lathrop, M, Goate, AM, Escott-Price, V, Seshadri, S, Pericak-Vance, MA, Amouyel, P, Williams, J, Van Duijn, CM, Schellenberg, GD, Farrer, LA
APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4dfc181ad7b04eb3f3078d1e74e920
Autor:
Jun, G, Ibrahim-Verbaas, CA, Vronskaya, M, Lambert, J-C, Chung, J, Naj, AC, Kunkle, BW, Wang, L-S, Bis, JC, Bellenguez, C, Harold, D, Lunetta, KL, Destefano, AL, Grenier-Boley, B, Sims, R, Beecham, GW, Smith, AV, Chouraki, V, Hamilton-Nelson, KL, Ikram, MA, Fievet, N, Denning, N, Martin, ER, Schmidt, H, Kamatani, Y, Dunstan, ML, Valladares, O, Laza, AR, Zelenika, D, Ramirez, A, Foroud, TM, Choi, S-H, Boland, A, Becker, T, Kukull, WA, van der Lee, SJ, Pasquier, F, Cruchaga, C, Beekly, D, Fitzpatrick, AL, Hanon, O, Gill, M, Barber, R, Gudnason, V, Campion, D, Love, S, Bennett, DA, Amin, N, Berr, C, Tsolaki, Magda, Buxbaum, JD, Lopez, OL, Deramecourt, V, Fox, NC, Cantwell, LB, Tárraga, L, Dufouil, C, Hardy, J, Crane, PK, Eiriksdottir, G, Hannequin, D, Clarke, R, Evans, D, Mosley, TH, Letenneur, L, Brayne, C, Maier, W, De Jager, P, Emilsson, V, Dartigues, J-F, Hampel, H, Kamboh, MI, de Bruijn, RFAG, Tzourio, C, Pastor, P, Larson, EB, Rotter, JI, O'Donovan, MC, Montine, TJ, Nalls, MA, Mead, S, Reiman, EM, Jonsson, PV, Holmes, C, St George-Hyslop, PH, Boada, M, Passmore, P, Wendland, JR, Schmidt, R, Morgan, K, Winslow, AR, Powell, JF, Carasquillo, M, Younkin, SG, Jakobsdóttir, J, Kauwe, JSK, Wilhelmsen, KC, Rujescu, D, Nöthen, MM, Hofman, A
Publikováno v:
Molecular psychiatry, vol 21, iss 1
APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cd47ff3240562f48271fd490e5ef55df
https://escholarship.org/uc/item/9rt9554g
https://escholarship.org/uc/item/9rt9554g
Autor:
Prins, BP, Abbasi, A, Wong, A, Vaez, A, Nolte, I, Franceschini, N, Stuart, PE, Guterriez Achury, J, Mistry, V, Bradfield, JP, Valdes, AM, Bras, J, Shatunov, A, PAGE Consortium, International Stroke Genetics Consortium, Systemic Sclerosis Consortium, Treat OA Consortium, DIAGRAM Consortium, CARDIoGRAMplusC4D Consortium, ALS Consortium, International Parkinson’s Disease Genomics Consortium, Autism Spectrum Disorder Working Group Of The Psychiatric Genomics Consortium, CKDGen Consortium, GERAD1 Consortium, International Consortium For Blood Pressure, Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Inflammation Working Group Of The CHARGE Consortium, Lu, C, Han, B, Raychaudhuri, S, Bevan, S, Mayes, MD, Tsoi, LC, Evangelou, E, Nair, RP, Grant, SFA, Polychronakos, C, Radstake, TRD, Van Heel, DA, Dunstan, ML, Wood, NW, Al-Chalabi, A, Dehghan, A, Hakonarson, H, Markus, HS, Elder, JT, Knight, J, Arking, DE, Spector, TD, Koeleman, BPC, Van Duijn, CM, Martin, J, Morris, AP, Weersma, RK, Wijmenga, C, Munroe, PB, Perry, JRB, Pouget, JG, Jamshidi, Y, Snieder, H, Alizadeh, BZ
BACKGROUND: C-reactive protein (CRP) is associated with immune, cardiometabolic, and psychiatric traits and diseases. Yet it is inconclusive whether these associations are causal. METHODS AND FINDINGS: We performed Mendelian randomization (MR) analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7564f9c3486c4028824f1f4720eb3f9a
Akademický článek
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Akademický článek
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Autor:
Prins BP; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom., Abbasi A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wong A; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.; Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran., Nolte I; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Franceschini N; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America., Stuart PE; Department of Dermatology, Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, United States of America., Guterriez Achury J; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Mistry V; Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, United States of America., Valdes AM; Department of Academic Rheumatology, University of Nottingham, Nottingham, United Kingdom., Bras J; Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom., Shatunov A; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Lu C; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Han B; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America., Raychaudhuri S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Division of Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Partners HealthCare Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America.; Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom., Bevan S; Neurology Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Mayes MD; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Tsoi LC; Department of Dermatology, Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Evangelou E; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Nair RP; Department of Dermatology, Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, United States of America., Grant SF; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, United States of America.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America., Polychronakos C; Endocrine Genetics Research Institute, McGill University Health Center, Montreal, Quebec, Canada., Radstake TR; Department of Rheumatology & Clinical Immunology and Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., van Heel DA; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Dunstan ML; Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom., Wood NW; Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom., Al-Chalabi A; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; Complex Disease Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America., Dehghan A; Department of Epidemiology, Erasmus University Rotterdam, University Medical Centre Rotterdam, Rotterdam, the Netherlands., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, United States of America.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America., Markus HS; Neurology Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Elder JT; Department of Dermatology, Veterans Affairs Hospital, University of Michigan, Ann Arbor, Michigan, United States of America., Knight J; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Arking DE; McKusick-Nathans Institute of Genetic Medicine and Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Koeleman BP; Complex Genetic Section, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus University Rotterdam, University Medical Centre Rotterdam, Rotterdam, the Netherlands., Martin J; Instituto de Parasitologia y Biomedicina Lopez-Neyra, Consejo Superior de Investigaciones Científicas, Granada, Spain., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom., Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wijmenga C; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Munroe PB; NIHR Barts Cardiovascular Biomedical Research Unit, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.; Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom., Perry JR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom., Pouget JG; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Jamshidi Y; Cardiogenetics Lab, Cardiovascular and Cell Sciences Institute, St George's Hospital Medical School, London, United Kingdom., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Publikováno v:
PLoS medicine [PLoS Med] 2016 Jun 21; Vol. 13 (6), pp. e1001976. Date of Electronic Publication: 2016 Jun 21 (Print Publication: 2016).
Autor:
Jun G; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Ibrahim-Verbaas CA; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands.; Department of Neurology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Vronskaya M; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Lambert JC; Inserm U744, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, Lille, France., Chung J; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA., Naj AC; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Kunkle BW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Bellenguez C; Inserm U744, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, Lille, France., Harold D; Trinity College, University of Dublin, Dublin, Ireland., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Destefano AL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Grenier-Boley B; Inserm U744, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, Lille, France., Sims R; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Beecham GW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA., Smith AV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Chouraki V; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Hamilton-Nelson KL; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands.; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.; Department of Radiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Fievet N; Inserm U744, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, Lille, France., Denning N; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Martin ER; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA., Schmidt H; Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Kamatani Y; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, Riken, Kanagawa, Japan.; Foundation Jean Dausset-CEPH, Paris, France., Dunstan ML; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Laza AR; Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain., Zelenika D; Centre National de Genotypage, Institut Genomique, Commissariat a l'energie Atomique, Evry, France., Ramirez A; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.; Institute of Human Genetics, University of Bonn, Bonn, Germany., Foroud TM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA., Choi SH; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Boland A; Centre National de Genotypage, Institut Genomique, Commissariat a l'energie Atomique, Evry, France., Becker T; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany., Kukull WA; Department of Epidemiology, University of Washington, Seattle, WA, USA., van der Lee SJ; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Pasquier F; Université Lille 2, Lille, France.; Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France., Cruchaga C; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, MO, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA., Fitzpatrick AL; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Departments of Health Services, University of Washington, Seattle, WA, USA., Hanon O; Department of Geriatrics, University Paris Descartes, Sorbonne Paris V, France.; Geriatrics Department, Broca Hospital, Paris, France., Gill M; Mercer's Institute for Research on Aging, St James Hospital and Trinity College, Dublin, Ireland., Barber R; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Gudnason V; University of Iceland, Faculty of Medicine, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Campion D; CNR-MAJ, Inserm U1079, Rouen, France; University Hospital, 76031 Rouen, France.; University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, UK., Love S; University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, UK., Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Berr C; Inserm U888, Hôpital La Colombière, Montpellier, France., Tsolaki M; Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece., Buxbaum JD; Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA.; Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA.; Departments of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY, USA., Lopez OL; University of Pittsburgh Alzheimer's Disease Research Center, Pittsburgh, PA, USA.; Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Deramecourt V; Université Lille 2, Lille, France.; Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK., Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Tárraga L; Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain., Dufouil C; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Hardy J; Department of Molecular Neuroscience, Institute of Neurology, London, UK.; Reta Lilla Weston Laboratories, Institute of Neurology, London, UK., Crane PK; Department of Medicine, University of Washington, Seattle, WA, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Hannequin D; CNR-MAJ, Inserm U1079, Rouen, France; University Hospital, 76031 Rouen, France.; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Clarke R; Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, UK., Evans D; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA., Mosley TH Jr; Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, MS, USA., Letenneur L; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Brayne C; Institute of Public Health, University of Cambridge, Cambridge, UK., Maier W; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., De Jager P; Department of Neurology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands.; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology and Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Emilsson V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland., Dartigues JF; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France.; Centre de Mémoire de Ressources et de Recherche de Bordeaux, CHU de Bordeaux, Bordeaux, France., Hampel H; Department of Psychiatry, University of Frankfurt, Frankfurt am Main, Germany.; Department of Psychiatry, Ludwig Maximilians University, Munich, Germany., Kamboh MI; University of Pittsburgh Alzheimer's Disease Research Center, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA., de Bruijn RF; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Tzourio C; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Pastor P; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain., Larson EB; Department of Medicine, University of Washington, Seattle, WA, USA.; Group Health, Group Health Research Institute, Seattle, WA, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., O'Donovan MC; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Montine TJ; Department of Pathology, University of Washington, Seattle, WA, USA., Nalls MA; Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA., Mead S; Department of Molecular Neuroscience, Institute of Neurology, London, UK., Reiman EM; Arizona Alzheimer's Consortium, Phoenix, AZ, USA.; Department of Psychiatry, University of Arizona, Phoenix, AZ, USA.; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona., Jonsson PV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland.; Department of Geriatrics, Landspitali National University Hospital, Reykjavik, Iceland., Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK., St George-Hyslop PH; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON, Canada.; Cambridge Institute for Medical Research and Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Boada M; Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain., Passmore P; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK., Wendland JR; PharmaTherapeutics Clinical Research, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Schmidt R; Department of Neurology, Medical University of Graz, Graz, Austria., Morgan K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Winslow AR; PharmaTherapeutics Clinical Research, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Powell JF; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, UK., Carasquillo M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Jakobsdóttir J; Icelandic Heart Association, Kopavogur, Iceland., Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah, USA., Wilhelmsen KC; Department of Genetics, University of North Carolina Chapel Hill, Chapel Hill, NC, USA., Rujescu D; Department of Psychiatry, Psychotherapy and Psychosomatics Martin-Luther-University Halle-Wittenberg, Halle, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands.; Department of Radiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Jones L; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Haines JL; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Departments of Health Services, University of Washington, Seattle, WA, USA.; Group Health, Group Health Research Institute, Seattle, WA, USA., Van Broeckhoven C; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Holmans P; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, MD, USA., Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., Lathrop M; Foundation Jean Dausset-CEPH, Paris, France.; Centre National de Genotypage, Institut Genomique, Commissariat a l'energie Atomique, Evry, France.; McGill University and Génome Québec Innovation Centre, Montreal, QC, Canada., Goate AM; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, MO, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Escott-Price V; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA., Amouyel P; Inserm U744, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, Lille, France.; University Hospital, CHRU Lille, Lille, France., Williams J; Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Erasmus, Rotterdam,The Netherlands., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Farrer LA; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Publikováno v:
Molecular psychiatry [Mol Psychiatry] 2016 Jan; Vol. 21 (1), pp. 108-17. Date of Electronic Publication: 2015 Mar 17.
Autor:
Escott-Price V; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Bellenguez C; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France., Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Choi SH; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Harold D; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Jones L; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Holmans P; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Gerrish A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Vedernikov A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Richards A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., DeStefano AL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Lambert JC; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France., Ibrahim-Verbaas CA; Department of Epidemiology and Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Naj AC; Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Sims R; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Jun G; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America., Beecham GW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America., Grenier-Boley B; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France., Russo G; Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland., Thornton-Wells TA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America., Denning N; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Smith AV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Icelandic Heart Association, Kopavogur, Iceland., Chouraki V; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America., Thomas C; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Ikram MA; Departments of Epidemiology, Neurology and Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands., Zelenika D; Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France., Vardarajan BN; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America., Kamatani Y; Fondation Jean Dausset- CEPH, Paris, France., Lin CF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Schmidt H; Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Kunkle B; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America., Dunstan ML; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Vronskaya M; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Johnson AD; NHLBI Cardiovascular Epidemiology and Human Genomics Branch, The Framingham Heart Study, Framingham, Massachusetts, United States of America., Ruiz A; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain., Bihoreau MT; Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France., Reitz C; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America., Pasquier F; Université Lille 2, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France., Hollingworth P; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Hanon O; University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics department, Paris, France., Fitzpatrick AL; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Global Health, University of Washington, Seattle, Washington, United States of America., Buxbaum JD; Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America; Departments of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America., Campion D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France., Crane PK; Department of Medicine, University of Washington, Seattle, Washington, United States of America., Baldwin C; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America., Becker T; German Center for Neurodegenerative Diseases (DZNE), Bonn, and Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany., Gudnason V; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Icelandic Heart Association, Kopavogur, Iceland., Cruchaga C; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America., Craig D; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Amin N; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Berr C; INSERM U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France., Lopez OL; Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., De Jager PL; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts, United States of America., Deramecourt V; Université Lille 2, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France., Johnston JA; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Evans D; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America., Lovestone S; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom., Letenneur L; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Hernández I; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain., Rubinsztein DC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Sleegers K; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Goate AM; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America., Fiévet N; Inserm U744, Lille, France; Institut Pasteur de Lille, Lille, France., Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America., Gill M; Discipline of Psychiatry, Trinity College, Dublin, Ireland., Brown K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom., Kamboh MI; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Keller L; Aging Reasearch Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Barberger-Gateau P; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom., McGuinness B; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Larson EB; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health, Seattle, Washington, United States of America., Myers AJ; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Dufouil C; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France., Todd S; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Wallon D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France., Love S; University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, United Kingdom., Rogaeva E; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Gallacher J; Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom., George-Hyslop PS; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada; Cambridge Institute for Medical Research and Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Clarimon J; Neurology Department. IIB Sant Pau. Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain; Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain., Lleo A; Neurology Department. IIB Sant Pau. Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain; Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain., Bayer A; Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom., Tsuang DW; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America., Yu L; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America., Tsolaki M; 3rd Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece., Bossù P; Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy., Spalletta G; Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy., Proitsi P; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom., Collinge J; MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom., Sorbi S; NEUROFARBA Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy., Garcia FS; Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain., Fox NC; Dementia Research Center, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom., Hardy J; Department of Molecular Neuroscience and Reta Lilla Weston Laboratories, Institute of Neurology, London, United Kingdom., Naranjo MC; Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain., Bosco P; IRCCS Associazione Oasi Maria SS, Troina, Italy., Clarke R; Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom., Brayne C; Cognitive Function and Ageing Study (CFAS), Institute of Public Health, University of Cambridge, Cambridge, United Kingdom., Galimberti D; University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy., Scarpini E; University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy., Bonuccelli U; Neurological Clinic, University of Pisa, Pisa, Italy., Mancuso M; Neurological Clinic, University of Pisa, Pisa, Italy., Siciliano G; Neurological Clinic, University of Pisa, Pisa, Italy., Moebus S; Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Mecocci P; Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy., Zompo MD; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Maier W; Department of Psychiatry and Psychotherapy, University of Bonn, Germany and German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany., Hampel H; Department of Psychiatry, University of Frankfurt am Main, Frankfurt am Main, Germany (H.H.); Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany., Pilotto A; Gerontology and Geriatrics Research Laboratory, I.R.C.C.S. Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy., Frank-García A; Centro de Biología Molecular Severo Ochoa (CSIC-UAM); Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto de Investigación Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain., Panza F; Department of Geriatrics,Center for Aging Brain,University of Bari, Bari, Italy., Solfrizzi V; Department of Geriatrics,Center for Aging Brain,University of Bari, Bari, Italy., Caffarra P; Department of Neuroscience-University of Parma, Parma, Italy; Center for Cognitive Disorders AUSL, Parma, Italy., Nacmias B; NEUROFARBA Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy., Perry W; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America., Mayhaus M; Department Of Psychiatry, University Hospital, Saarland, Germany., Lannfelt L; Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Pichler S; Department Of Psychiatry, University Hospital, Saarland, Germany., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America., Ingelsson M; Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden., Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, United States of America., Alvarez V; Genetica molecular-Huca-Oviedo, Oviedo, Spain., Zou F; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America., Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America., Coto E; Genetica molecular-Huca-Oviedo, Oviedo, Spain., Hamilton-Nelson KL; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America., Gu W; Department of Psychiatry, University Hospital, Saarland, Germany., Razquin C; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain., Pastor P; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain; CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Mateo I; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IFIMAV), Santander, Spain., Owen MJ; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Faber KM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America., Jonsson PV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Landspitali University Hospital, Reykjavik, Iceland., Combarros O; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IFIMAV), Santander, Spain., O'Donovan MC; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom., Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Soininen H; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Blacker D; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America., Mead S; MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom., Mosley TH Jr; Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America., Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America., Fratiglioni L; Aging Research Center, Department Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Department Geriatric Medicine, Genetics Unit, Karolinska University Hospital Huddinge, Stockholm, Sweden., Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, United Kingdom., de Bruijn RF; Departments of Neurology and Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Passmore P; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom., Montine TJ; Department of Pathology, University of Washington, Seattle, Washington, United States of America., Bettens K; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America., Brice A; INSERM UMR_S975-CNRS UMR 7225, Université Pierre et Marie Curie, Centre de recherche de l'Institut du Cerveau et de la Moëlle épinière-CRICM, Hôpital de la Salpêtrière, Paris France; AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France., Morgan K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom., Foroud TM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America., Kukull WA; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America., Hannequin D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France., Powell JF; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom., Nalls MA; Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America., Ritchie K; INSERM U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France; Imperial College, London, United Kingdom., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah, United States of America., Boerwinkle E; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America; Human Genetics Center and Div. of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas, United States of America., Riemenschneider M; Department of Psychiatry, University Hospital, Saarland, Germany., Boada M; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain; Hospital Universitari Vall d'Hebron - Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona, Spain., Hiltunen M; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Martin ER; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America., Schmidt R; Department of Neurology, Medical University Graz, Graz, Austria., Rujescu D; Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany., Dartigues JF; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France; Centre de Mémoire de Ressources et de Recherche de Bordeaux, CHU de Bordeaux, Bordeaux, France., Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America., Tzourio C; Inserm U708, Victor Segalen University, Bordeaux, France., Hofman A; Departments of Epidemiology, Neurology and Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands., Nöthen MM; Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, and German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany., Graff C; Department Geriatric Medicine, Genetics Unit, Karolinska University Hospital Huddinge, Stockholm, Sweden; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, KIADRC, Stockholm, Sweden., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America., Haines JL; Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America; Department of Epidemiology & Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America., Lathrop M; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America; Fondation Jean Dausset- CEPH, Paris, France; McGill University and Génome Québec Innovation Centre, Montreal, Canada., Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America., Van Broeckhoven C; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Farrer LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America., van Duijn CM; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands., Ramirez A; Department of Psychiatry and Psychotherapy and Institute of Human Genetics, University of Bonn, Bonn, Germany., Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; The Framingham Heart Study, Framingham, Massachusetts, United States of America., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Amouyel P; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France; Centre Hospitalier Régional Universitaire de Lille, Lille, France., Williams J; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Publikováno v:
PloS one [PLoS One] 2014 Jun 12; Vol. 9 (6), pp. e94661. Date of Electronic Publication: 2014 Jun 12 (Print Publication: 2014).
Autor:
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P
Publikováno v:
Nature genetics [Nat Genet] 2013 Dec; Vol. 45 (12), pp. 1452-8. Date of Electronic Publication: 2013 Oct 27.