HIV self-testing intervention experiences and kit usability: results from a qualitative study among men who have sex with men in the SELPHI (Self-Testing Public Health Intervention) randomized controlled trial in England and Wales

Autor: Witzel, TC, Bourne, A, Burns, FM, Rodger, AJ, McCabe, L, Gabriel, MM, Gafos, M, Ward, D, Collaco-Moraes, Y, Dunn, DT, Speakman, A, Bonell, C, Pebody, R, Lampe, FC, Harbottle, J, Phillips, AN, McCormack, S, Weatherburn, P

OBJECTIVES: SELPHI (HIV Self-Testing Public Health Intervention) is the largest randomized controlled trial (RCT) of HIV self-testing (HIVST) in a high-income setting to date, and has recruited 10 000 men who have sex with men (cis- and transgender)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::070e0005f661c498c486bc7d60ba2de7
https://researchonline.lshtm.ac.uk/id/eprint/4655562/1/Witzel-HIVST-intervention-experiences-and-kit-usability.pdf

Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance

Autor: Geretti, AM, White, E, Orkin, C, Tostevin, A, Tilston, P, Chadwick, D, Leen, C, Sabin, C, Dunn, DT, Asboe, D, Pozniak, A, Cane, P, Churchill, D, Clark, D, Collins, S, Delpech, V, Douthwaite, S, Dunn, D, Fearnhill, E, Porter, K, Stirrup, O, Fraser, C, Gunson, R, Hale, A, Hue, S, Lazarus, L, Leigh-Brown, A, Mbisa, T, Mackie, N, Nastouli, E, Pillay, D, Phillips, A, Smit, E, Templeton, K, Volz, E, Williams, I, Zhang, H, Dawkins, J, O'Shea, S, Mullen, J, Cox, A, Tandy, R, Fawcett, T, Hopkins, M, Booth, C, Garcia-Diaz, A, Renwick, L, Schmid, ML, Payne, B, Hubb, J, Dustan, S, Kirk, S, Bradley-Stewart, A, Ainsworth, J, Allan, S, Anderson, J, Babiker, A, Gazzard, B, Gilson, R, Gompels, M, Hay, P, Hill, T, Johnson, M, Jose, S, Kegg, S, Martin, F, Mital, D, Nelson, M, Palfreeman, A, Post, F, Pritchard, J, Sabin, CA, Schwenk, A, Tariq, A, Trevelion, R, Ustianowski, A, Walsh, J, Thornton, A, Huntington, S, Glabay, A, Shidfar, S, Lynch, J, Hand, J, De Souza, C, Perry, N, Tilbury, S, Youssef, E, Mabika, T, Mandalia, S, Munshi, S, Adefisan, A, Taylor, C, Gleisner, Z, Ibrahim, F, Campbell, L, Baillie, K, Brima, N, Miller, S, Wood, C, Youle, M, Lampe, F, Smith, C, Tsintas, R, Chaloner, C, Hutchinson, S, Winston, A, Weber, J, Ramzan, F, Carder, M, Wilson, A, Morris, S, Lewszuk, A, Faleye, A, Ogunbiyi, V, Mitchell, S, Kemble, C, Russell-Sharpe, S, Gravely, J, Harte, A, Spencer, H, Jones, R, Cumming, S, Atkinson, C, Edgell, V, Allen, J, Murphy, C, Gunder, I

Publikováno v: 2018, ' Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance ', Journal of Antimicrobial Chemotherapy . https://doi.org/10.1093/jac/dky468
Journal of Antimicrobial Chemotherapy

Objectives: In subjects with transmitted thymidine analogue mutations (TAMs), boosted PIs (PI/b) are often chosen to overcome possible resistance to the NRTI backbone. However, data to guide treatment selection are limited. Our aim was to obtain firm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e781fecbd6c3b33e563cc6c5c6c103
https://hdl.handle.net/20.500.11820/1316df3c-4049-460a-b302-e4b76d0e397e

An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs

Autor: Smit, E, White, E, Clark, D, Churchill, D, Zhang, H, Collins, S, Pillay, D, Sabin, C, Nelson, M, Winston, A, Jose, S, Tostevin, A, Dunn, DT, UK HIV Drug Resistance Database and the UK Collaborative HIV Cohort

Objectives: HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the strong association between viral subtype and confounding factors such as exposure gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::1a41baa41434554c81df016ae126284d
http://hdl.handle.net/10044/1/48099

Continuation of emtricitabine/lamivudine within combination antiretroviral therapy following detection of the M184V/I HIV‐1 resistance mutation.

Autor: Stirrup, OT, Asboe, D, Pozniak, A, Sabin, CA, Gilson, R, Mackie, NE, Tostevin, A, Hill, T, Dunn, DT, Chadwick, David, Churchill, Duncan, Clark, Duncan, Collins, Simon, Delpech, Valerie, Douthwaite, Samuel, Fearnhill, Esther, Porter, Kholoud, Fraser, Christophe, Geretti, Anna Maria, Gunson, Rory

Publikováno v: HIV Medicine; May2020, Vol. 21 Issue 5, p309-321, 13p

HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK

Autor: El Bouzidi, K, White, E, Mbisa, JL, Sabin, CA, Phillips, AN, Mackie, N, Pozniak, AL, Tostevin, A, Pillay, D, Dunn, DT

Background Darunavir is considered to have a high genetic barrier to resistance. Most darunavir-associated drug resistance mutations (DRMs) have been identified through correlation of baseline genotype with virological response in clinical trials. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::038e193664f5afdad86cf0ceb951d7a6
http://hdl.handle.net/10044/1/69611