SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity

Autor: Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E.D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Bucke, Ashlea, Calder, Jo, Canna, Laura, Domingo, Jason, Elmer, Anne, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O’Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Bullman, Ben, Dunmore, Benjamin J., Fawke, Stuart, Gräf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, Mescia, Federica, O’Donnell, Ciara, Pointon, Linda, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wood, Jennifer, Wylot, Marta, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Grenfell, Richard, Hinch, Andrew, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Nice, Francesca, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Stefanucci, Luca, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M.D.D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Allison, John, Butcher, Helen, Caputo, Daniela, Clapham-Riley, Debbie, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Phelan, Isabel, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Meng, Bo, Datir, Rawlings, Choi, Jinwook, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.

Publikováno v: In Cell Reports 16 August 2022 40(7)

Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

Autor: Bergamaschi, Laura, Mescia, Federica, Turner, Lorinda, Hanson, Aimee L., Kotagiri, Prasanti, Dunmore, Benjamin J., Ruffieux, Hélène, De Sa, Aloka, Huhn, Oisín, Morgan, Michael D., Gerber, Pehuén Pereyra, Wills, Mark R., Baker, Stephen, Calero-Nieto, Fernando J., Doffinger, Rainer, Dougan, Gordon, Elmer, Anne, Goodfellow, Ian G., Gupta, Ravindra K., Hosmillo, Myra, Hunter, Kelvin, Kingston, Nathalie, Lehner, Paul J., Matheson, Nicholas J., Nicholson, Jeremy K., Petrunkina, Anna M., Richardson, Sylvia, Saunders, Caroline, Thaventhiran, James E.D., Toonen, Erik J.M., Weekes, Michael P., Göttgens, Berthold, Toshner, Mark, Hess, Christoph, Bradley, John R., Lyons, Paul A., Smith, Kenneth G.C.

Publikováno v: In Immunity 8 June 2021 54(6):1257-1275

Reduced circulating BMP9 and pBMP10 in hospitalized COVID‐19 patients.

Autor: Dunmore, Benjamin J.^1,2, Upton, Paul D.^1,2, Auckland, Kate^1,2, Samanta, Romit J.^1,2,3, Lyons, Paul A.^2,4, Smith, Kenneth G. C.^2,3,4,5, Gräf, Stefan^1,2, Summers, Charlotte^1,2,3, Morrell, Nicholas W.^1,2,3 nwm23@cam.ac.uk

Publikováno v: Pulmonary Circulation. Jan2023, Vol. 13 Issue 1, p1-8. 8p.

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SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

Autor: Mlcochova, Petra, Kemp, Steven A., Dhar, Mahesh Shanker, Papa, Guido, Meng, Bo, Ferreira, Isabella A. T. M., Datir, Rawlings, Collier, Dami A., Albecka, Anna, Singh, Sujeet, Pandey, Rajesh, Brown, Jonathan, Zhou, Jie, Goonawardane, Niluka, Mishra, Swapnil, Whittaker, Charles, Mellan, Thomas, Marwal, Robin, Datta, Meena, Sengupta, Shantanu, Ponnusamy, Kalaiarasan, Radhakrishnan, Venkatraman Srinivasan, Abdullahi, Adam, Charles, Oscar, Chattopadhyay, Partha, Devi, Priti, Caputo, Daniela, Peacock, Tom, Wattal, Chand, Goel, Neeraj, Satwik, Ambrish, Vaishya, Raju, Agarwal, Meenakshi, Chauhan, Himanshu, Dikid, Tanzin, Gogia, Hema, Lall, Hemlata, Verma, Kaptan, Singh, Manoj K., Soni, Namita, Meena, Namonarayan, Madan, Preeti, Singh, Priyanka, Sharma, Ramesh, Sharma, Rajeev, Kabra, Sandhya, Kumar, Sattender, Kumari, Swati, Sharma, Uma, Chaudhary, Urmila, Sivasubbu, Sridhar, Scaria, Vinod, Oberoi, J. K., Raveendran, Reena, Datta, S., Das, Saumitra, Maitra, Arindam, Chinnaswamy, Sreedhar, Biswas, Nidhan Kumar, Parida, Ajay, Raghav, Sunil K., Prasad, Punit, Sarin, Apurva, Mayor, Satyajit, Ramakrishnan, Uma, Palakodeti, Dasaradhi, Seshasayee, Aswin Sai Narain, Thangaraj, K., Bashyam, Murali Dharan, Dalal, Ashwin, Bhat, Manoj, Shouche, Yogesh, Pillai, Ajay, Abraham, Priya, Potdar, Varsha Atul, Cherian, Sarah S., Desai, Anita Sudhir, Pattabiraman, Chitra, Manjunatha, M. V., Mani, Reeta S., Udupi, Gautam Arunachal, Nandicoori, Vinay, Tallapaka, Karthik Bharadwaj, Sowpati, Divya Tej, Kawabata, Ryoko, Morizako, Nanami, Sadamasu, Kenji, Asakura, Hiroyuki, Nagashima, Mami, Yoshimura, Kazuhisa, Ito, Jumpei, Kimura, Izumi, Uriu, Keiya, Kosugi, Yusuke, Suganami, Mai, Oide, Akiko, Yokoyama, Miyabishara, Chiba, Mika, Saito, Akatsuki, Butlertanaka, Erika P., Tanaka, Yuri L., Ikeda, Terumasa, Motozono, Chihiro, Nasser, Hesham, Shimizu, Ryo, Yuan, Yue, Kitazato, Kazuko, Hasebe, Haruyo, Nakagawa, So, Wu, Jiaqi, Takahashi, Miyoko, Fukuhara, Takasuke, Shimizu, Kenta, Tsushima, Kana, Kubo, Haruko, Shirakawa, Kotaro, Kazuma, Yasuhiro, Nomura, Ryosuke, Horisawa, Yoshihito, Takaori-Kondo, Akifumi, Tokunaga, Kenzo, Ozono, Seiya, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E. D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Bucke, Ashlea, Calder, Jo, Canna, Laura, Domingo, Jason, Elmer, Anne, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O'Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Bullman, Ben, Dunmore, Benjamin J., Fawke, Stuart, Graf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, Mescia, Federica, O'Donnell, Ciara, Pointon, Linda, Pond, Nicole, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wood, Jennifer, Wylot, Marta, Bergamaschi, Laura, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Grenfell, Richard, Hinch, Andrew, Huhn, Oisin, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Lewis, Daniel, Marsden, Joe, Nice, Francesca, Okecha, Georgina, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Yarkoni, Natalia Savinykh, Sharma, Rahul, Stefanucci, Luca, Stephens, Jonathan, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M. D. D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Rossi, Sabrina, Selvan, Mayurun, Spencer, Sarah, Yong, Cissy, Allison, John, Butcher, Helen, Clapham-Riley, Debbie, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Kasanicki, Mary, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Phelan, Isabel, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Mavousian, Antranik, Lee, Joo Hyeon, Bassi, Jessica, Silacci-Fegni, Chiara, Saliba, Christian, Pinto, Dora, Irie, Takashi, Yoshida, Isao, Hamilton, William L., Sato, Kei, Bhatt, Samir, Flaxman, Seth, James, Leo C., Corti, Davide, Piccoli, Luca, Barclay, Wendy S., Rakshit, Partha, Agrawal, Anurag, Gupta, Ravindra K.

Publikováno v: Mlcochova, P, Kemp, S A, Dhar, M S, Papa, G, Meng, B, Ferreira, I A T M, Datir, R, Collier, D A, Albecka, A, Singh, S, Pandey, R, Brown, J, Zhou, J, Goonawardane, N, Mishra, S, Whittaker, C, Mellan, T, Marwal, R, Datta, M, Sengupta, S, Ponnusamy, K, Radhakrishnan, V S, Abdullahi, A, Charles, O, Chattopadhyay, P, Devi, P, Caputo, D, Peacock, T, Wattal, C, Goel, N, Satwik, A, Vaishya, R, Agarwal, M, Chauhan, H, Chauhan, H, Dikid, T, Gogia, H, Lall, H, Verma, K, Dhar, M S, Singh, M K, Soni, N, Meena, N, Madan, P, Singh, P, Sharma, R, Sharma, R, Kabra, S, Kumar, S, Kumari, S, Sharma, U, Chaudhary, U, Sivasubbu, S, Scaria, V, Oberoi, J K, Raveendran, R, Datta, S, Das, S, Maitra, A, Chinnaswamy, S, Biswas, N K, Parida, A, Raghav, S K, Prasad, P, Sarin, A, Mayor, S, Ramakrishnan, U, Palakodeti, D, Seshasayee, A S N, Thangaraj, K, Bashyam, M D, Dalal, A, Bhat, M, Shouche, Y, Pillai, A, Abraham, P, Potdar, V A, Cherian, S S, Desai, A S, Pattabiraman, C, Manjunatha, M V, Mani, R S, Udupi, G A, Nandicoori, V, Tallapaka, K B, Sowpati, D T, Kawabata, R, Kawabata, R, Morizako, N, Sadamasu, K, Asakura, H, Nagashima, M, Yoshimura, K, Ito, J, Kimura, I, Uriu, K, Kosugi, Y, Suganami, M, Oide, A, Yokoyama, M, Chiba, M, Saito, A, Butlertanaka, E P, Tanaka, Y L, Ikeda, T, Motozono, C, Nasser, H, Shimizu, R, Yuan, Y, Kitazato, K, Hasebe, H, Nakagawa, S, Wu, J, Takahashi, M, Fukuhara, T, Shimizu, K, Tsushima, K, Kubo, H, Shirakawa, K, Kazuma, Y, Nomura, R, Horisawa, Y, Takaori-Kondo, A, Tokunaga, K, Ozono, S, Baker, S, Baker, S, Dougan, G, Hess, C, Kingston, N, Lehner, P J, Lyons, P A, Matheson, N J, Owehand, W H, Saunders, C, Summers, C, Thaventhiran, J E D, Toshner, M, Weekes, M P, Maxwell, P, Shaw, A, Bucke, A, Calder, J, Canna, L, Domingo, J, Elmer, A, Fuller, S, Harris, J, Hewitt, S, Kennet, J, Jose, S, Kourampa, J, Meadows, A, O'Brien, C, Price, J, Publico, C, Rastall, R, Ribeiro, C, Rowlands, J, Ruffolo, V, Tordesillas, H, Bullman, B, Dunmore, B J, Fawke, S, Graf, S, Hodgson, J, Huang, C, Hunter, K, Jones, E, Legchenko, E, Matara, C, Martin, J, Mescia, F, O'Donnell, C, Pointon, L, Pond, N, Shih, J, Sutcliffe, R, Tilly, T, Treacy, C, Tong, Z, Wood, J, Wylot, M, Bergamaschi, L, Betancourt, A, Bower, G, Cossetti, C, De Sa, A, Epping, M, Fawke, S, Gleadall, N, Grenfell, R, Hinch, A, Huhn, O, Jackson, S, Jarvis, I, Krishna, B, Lewis, D, Marsden, J, Nice, F, Okecha, G, Omarjee, O, Perera, M, Potts, M, Richoz, N, Romashova, V, Yarkoni, N S, Sharma, R, Stefanucci, L, Stephens, J, Strezlecki, M, Turner, L, De Bie, E M D D, Bunclark, K, Josipovic, M, Mackay, M, Rossi, S, Selvan, M, Spencer, S, Yong, C, Allison, J, Butcher, H, Caputo, D, Clapham-Riley, D, Dewhurst, E, Furlong, A, Graves, B, Gray, J, Ivers, T, Kasanicki, M, Le Gresley, E, Linger, R, Meloy, S, Muldoon, F, Ovington, N, Papadia, S, Phelan, I, Stark, H, Stirrups, K E, Townsend, P, Walker, N, Webster, J, Scholtes, I, Hein, S, King, R, Mavousian, A, Lee, J H, Bassi, J, Silacci-Fegni, C, Saliba, C, Pinto, D, Irie, T, Yoshida, I, Hamilton, W L, Sato, K, Bhatt, S, Flaxman, S, James, L C, Corti, D, Piccoli, L, Barclay, W S, Rakshit, P, Agrawal, A, Gupta, R K & Mishra, S 2021, ' SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion ', Nature, vol. 599, pp. 114-119 . https://doi.org/10.1038/s41586-021-03944-y
Nature

The B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-existing lineages including B.1.617.1 (Kappa) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d15d086906aa18db47f0ee053650ce
https://doi.org/10.1038/s41586-021-03944-y