Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Dunjin Chen"'
Autor:
Shilei Bi, Lijun Huang, Yongjie Chen, Zhenhua Hu, Shanze Li, Yifan Wang, Baoying Huang, Lizi Zhang, Yuanyuan Huang, Beibei Dai, Lili Du, Zhaowei Tu, Yijing Wang, Dan Xu, Xiaotong Xu, Wen Sun, Julia Kzhyshkowska, Haibin Wang, Dunjin Chen, Fengchao Wang, Shuang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Abnormal trophoblast self-renewal and differentiation during early gestation is the major cause of miscarriage, yet the underlying regulatory mechanisms remain elusive. Here, we show that trophoblast specific deletion of Kat8, a MYST family
Externí odkaz:
https://doaj.org/article/a68412fcc31c4e5f985049702cf0d822
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesPreeclampsia/eclampsia (PE), a critical complication during pregnancy, has been suggested to correlate with immune cell phenotypes and levels of circulating inflammatory proteins. Our study aimed to employ a two-sample mendelian randomizati
Externí odkaz:
https://doaj.org/article/97f736e5d2ad45c2ba99d66db237193d
Autor:
Jiao Liu, Dunjin Chen, Huixia Yang, Xiaotian Li, Ka Chun Chong, Rong Zhou, Liona Poon, Hao Ying, Xiaohong Lu, Lixia Shen, Daljit Sahota, Long Nguyen-Hoang, Qiongjie Zhou, Chi Chiu Wang, Weirong Gu, Yanmin Jiang
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Pre-eclampsia (PE) affects about 5% of Chinese pregnant women and is a major cause of maternal and perinatal morbidity and mortality. The first trimester screening model developed by the Fetal Medicine Foundation, which uses the Bayes th
Externí odkaz:
https://doaj.org/article/3083ac6a3b8e42dd896b2d75f6c6cb5d
Autor:
Yingyu Liang, Siying Lai, Lijun Huang, Yulian Li, Shanshan Zeng, Shuang Zhang, Jingsi Chen, Wenbo Deng, Yu Liu, Jingying Liang, Pei Xu, Mingxing Liu, Zhongtang Xiong, Dunjin Chen, Zhaowei Tu, Lili Du
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Decidualization of human endometrial stromal cells (hESCs) is essential for the maintenance of pregnancy, which depends on the fine-tuned regulation of hESCs survival, and its perturbation contributes to pregnancy loss. However, the underlyi
Externí odkaz:
https://doaj.org/article/a7c83c468b324b1fa04d3fad773d5041
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Gastroschisis has increased globally over recent decades, and this increase has not been explained by identified risk factors. We conducted a population-based study of infants born in Canada, 2004–2020. We used “winter” months (i.e., S
Externí odkaz:
https://doaj.org/article/a8598129f9d34b5996059a75e16f9d86
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundThe interplay between gut microbiome genera and inflammatory kidney-related diseases, such as nephrotic syndrome, glomerulonephritis, tubulo-interstitial nephritis, and chronic kidney disease, has been observed. However, the causal relation
Externí odkaz:
https://doaj.org/article/a2d40ac0b5a34cc19da80f50a8aeade9
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 3, p 253 (2024)
Rare gene variants have been found to play a role in complex disorders. Preeclampsia, and especially early-onset preeclampsia, has a strong genetic link. However, the role of rare variants in the offspring of mothers with preeclampsia remains unclear
Externí odkaz:
https://doaj.org/article/9f340ff6e0934653a3d6067bea9e9374
Autor:
Lijun Huang, Zhaowei Tu, Liudan Wei, Wei Sun, Yifan Wang, Shilei Bi, Fang He, Lili Du, Jingsi Chen, Julia Kzhyshkowska, Haibin Wang, Dunjin Chen, Shuang Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract The interaction between trophoblasts, stroma cells, and immune cells at the maternal–fetal interface constitutes the functional units of the placenta, which is crucial for successful pregnancy outcomes. However, the investigation of this i
Externí odkaz:
https://doaj.org/article/112ae84dd4b247daa9a134e6d2d911e9
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Embryo implantation and placentation play pivotal roles in pregnancy by facilitating crucial maternal-fetal interactions. These dynamic processes involve significant alterations in gene expression profiles within the endometrium and trophoblast linea
Externí odkaz:
https://doaj.org/article/542c55e29665476289124d67fd60622c
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background In recent years, with the development of monitoring conditions and the application of pulmonary vascular-targeted drugs, pregnancy outcomes in women with pulmonary hypertension (PH) have improved, but the maternal mortality rate i
Externí odkaz:
https://doaj.org/article/6763c5579009484ba38dabc8b0e9ec3c