Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Dunja, Bruder"'
Autor:
Tanya Dogra, Lars Pelz, Julia D. Boehme, Jan Kuechler, Olivia Kershaw, Pavel Marichal-Gallardo, Maike Baelkner, Marc D. Hein, Achim D. Gruber, Dirk Benndorf, Yvonne Genzel, Dunja Bruder, Sascha Y. Kupke, Udo Reichl
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard vir
Externí odkaz:
https://doaj.org/article/14074a084c1e479b80e20d113a9f8b14
Autor:
Belinda Camp, Ilka Jorde, Franka Sittel, Alexander Pausder, Andreas Jeron, Dunja Bruder, Jens Schreiber, Sabine Stegemann-Koniszewski
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAllergic asthma has been mainly attributed to T helper type 2 (Th2) and proinflammatory responses but many cellular processes remain elusive. There is increasing evidence for distinct roles for macrophage and dendritic cell (DC) subsets i
Externí odkaz:
https://doaj.org/article/ab7ba096fd1c41d786620dd68e8f5131
Autor:
Katrin Vogel, Aditya Arra, Holger Lingel, Dirk Bretschneider, Florian Prätsch, Denny Schanze, Martin Zenker, Silke Balk, Dunja Bruder, Robert Geffers, Thomas Hachenberg, Christoph Arens, Monika C. Brunner-Weinzierl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Microbial infections early in life are challenging for the unexperienced immune system. The SARS-CoV-2 pandemic again has highlighted that neonatal, infant, child, and adult T-helper(Th)-cells respond differently to infections, and requires
Externí odkaz:
https://doaj.org/article/d80b20045d7949eebfdb45342967d917
Autor:
Sabine Brandt, Anja Bernhardt, Saskia Häberer, Katharina Wolters, Fabian Gehringer, Charlotte Reichardt, Anna Krause, Robert Geffers, Sascha Kahlfuß, Andreas Jeron, Dunja Bruder, Jonathan A. Lindquist, Berend Isermann, Peter R. Mertens
Publikováno v:
Cells, Vol 13, Iss 5, p 367 (2024)
Background: Fibrosis is characterized by excessive extracellular matrix formation in solid organs, disrupting tissue architecture and function. The Y-box binding protein-1 (YB-1) regulates fibrosis-related genes (e.g., Col1a1, Mmp2, and Tgfβ1) and c
Externí odkaz:
https://doaj.org/article/450014d8c91f4f63bde53aa7627b9c00
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
MAIT cells are multifunctional innate-like effector cells recognizing bacterial-derived vitamin B metabolites presented by the non-polymorphic MHC class I related protein 1 (MR1). However, our understanding of MR1-mediated responses of MAIT cells upo
Externí odkaz:
https://doaj.org/article/2ad405d16cf840c0a1e5ef2e5f3cebd2
Autor:
Suneet Singh Jhutty, Julia D. Boehme, Andreas Jeron, Julia Volckmar, Kristin Schultz, Jens Schreiber, Klaus Schughart, Kai Zhou, Jan Steinheimer, Horst Stöcker, Sabine Stegemann-Koniszewski, Dunja Bruder, Esteban A. Hernandez-Vargas
Publikováno v:
mSystems, Vol 7, Iss 6 (2022)
ABSTRACT The tracking of pathogen burden and host responses with minimally invasive methods during respiratory infections is central for monitoring disease development and guiding treatment decisions. Utilizing a standardized murine model of respirat
Externí odkaz:
https://doaj.org/article/e85ed8bd12404d7b94641691699c9528
Autor:
Sarah Frentzel, Andreas Jeron, Alexander Pausder, Olivia Kershaw, Julia Volckmar, Ingo Schmitz, Dunja Bruder
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IκB proteins regulate the inhibition and activation of NF-κB transcription factor complexes. While classical IκB proteins keep NF-κB complexes inactive in the cytoplasm, atypical IκB proteins act on activated NF-κB complexes located in the nucl
Externí odkaz:
https://doaj.org/article/77665caf5a0a49febcdda61e645d7bf8
Autor:
Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D. Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer, Astrid M. Westendorf, Torben Knuschke
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105540- (2022)
Summary: CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb
Externí odkaz:
https://doaj.org/article/13de89e0b0ca48f9bd746945964e9b6d
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/1faa14c2b74e43ff86d62b86f4084a82
Autor:
Clemens Cammann, Nicole Israel, Sarah Frentzel, Andreas Jeron, Eylin Topfstedt, Thomas Schüler, Luca Simeoni, Martin Zenker, Hans Joerg Fehling, Burkhart Schraven, Dunja Bruder, Ulrike Seifert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Upon antigen recognition by the T cell receptor (TCR), a complex signaling network orchestrated by protein-tyrosine kinases (PTKs) and protein-tyrosine phosphatases (PTPs) regulates the transmission of the extracellular signal to the nucleus. The rol
Externí odkaz:
https://doaj.org/article/31a0a97d2f9f4dbeb8c340c3bfd11b06