Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity.

Autor: Turnbull ML; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Wise HM; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Nicol MQ; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Smith N; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Dunfee RL; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Beard PM; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Jagger BW; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA Department of Pathology, Division of Virology, University of Cambridge, Cambridge, United Kingdom., Ligertwood Y; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Hardisty GR; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Xiao H; The Francis Crick Institute, Mill Hill Laboratory, Mill Hill, London, United Kingdom., Benton DJ; The Francis Crick Institute, Mill Hill Laboratory, Mill Hill, London, United Kingdom., Coburn AM; The Centre for Virus Research, The University of Glasgow, Glasgow, United Kingdom., Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA., McCauley JW; The Francis Crick Institute, Mill Hill Laboratory, Mill Hill, London, United Kingdom., Taubenberger JK; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Lycett SJ; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Weekes MP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom., Dutia BM; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom., Digard P; Division of Infection and Immunity, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, Edinburgh, United Kingdom paul.digard@roslin.ed.ac.uk.

Publikováno v: Journal of virology [J Virol] 2016 Sep 29; Vol. 90 (20), pp. 9263-84. Date of Electronic Publication: 2016 Sep 29 (Print Publication: 2016).

Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice.

Autor: Kash JC; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: kashj@niaid.nih.gov., Xiao Y; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Davis AS; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Walters KA; Institute for Systems Biology, Seattle, WA 98109, USA., Chertow DS; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA., Easterbrook JD; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Dunfee RL; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Sandouk A; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Jagger BW; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Schwartzman LM; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Kuestner RE; Institute for Systems Biology, Seattle, WA 98109, USA., Wehr NB; Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA., Huffman K; Pulmonary Center, Department of Medicine, Boston University Medical School, Boston, MA 02118, USA., Rosenthal RA; Pulmonary Center, Department of Medicine, Boston University Medical School, Boston, MA 02118, USA., Ozinsky A; Institute for Systems Biology, Seattle, WA 98109, USA., Levine RL; Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA., Doctrow SR; Pulmonary Center, Department of Medicine, Boston University Medical School, Boston, MA 02118, USA., Taubenberger JK; Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Publikováno v: Free radical biology & medicine [Free Radic Biol Med] 2014 Feb; Vol. 67, pp. 235-47. Date of Electronic Publication: 2013 Oct 17.

Obese mice have increased morbidity and mortality compared to non-obese mice during infection with the 2009 pandemic H1N1 influenza virus.

Autor: Easterbrook JD; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-3203, USA., Dunfee RL, Schwartzman LM, Jagger BW, Sandouk A, Kash JC, Memoli MJ, Taubenberger JK

Publikováno v: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2011 Nov; Vol. 5 (6), pp. 418-25. Date of Electronic Publication: 2011 Apr 18.

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

Autor: Sterjovski J; Macfarlane Burnet Institute for Medical Research & Public Health, Melbourne, Victoria, Australia. Jasminka@burnet.edu.au, Churchill MJ, Ellett A, Gray LR, Roche MJ, Dunfee RL, Purcell DF, Saksena N, Wang B, Sonza S, Wesselingh SL, Karlsson I, Fenyo EM, Gabuzda D, Cunningham AL, Gorry PR

Publikováno v: Retrovirology [Retrovirology] 2007 Dec 12; Vol. 4, pp. 89. Date of Electronic Publication: 2007 Dec 12.

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

Autor: Gorry PR; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA., Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D

Publikováno v: Virology [Virology] 2007 May 25; Vol. 362 (1), pp. 163-78. Date of Electronic Publication: 2007 Jan 18.