The HIV Env Variant N283 Enhances Macrophage Tropism and Is Associated with Brain Infection and Dementia

Autor: Dunfee, Rebecca L., Thomas, Elaine R., Gorry, Paul R., Wang, Jianbin, Taylor, Joann, Kunstman, Kevin, Wolinsky, Steven M., Gabuzda, Dana

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2006 Oct 01. 103(41), 15160-15165.

Externí odkaz: https://www.jstor.org/stable/30051519

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Autor: Wang Bin, Saksena Nitin, Purcell Damian FJ, Dunfee Rebecca L, Roche Michael J, Gray Lachlan R, Ellett Anne, Churchill Melissa J, Sterjovski Jasminka, Sonza Secondo, Wesselingh Steven L, Karlsson Ingrid, Fenyo Eva-Maria, Gabuzda Dana, Cunningham Anthony L, Gorry Paul R

Publikováno v: Retrovirology, Vol 4, Iss 1, p 89 (2007)

Abstract Background CCR5-restricted (R5) human immunodeficiency virus type 1 (HIV-1) variants cause CD4+ T-cell loss in the majority of individuals who progress to AIDS, but mechanisms underlying the pathogenicity of R5 strains are poorly understood.

Externí odkaz: https://doaj.org/article/167d98a13939480d8a01f23df55472b8

Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

Autor: Turnbull, Matthew L, Wise, Helen M, Nicol, Marlynne Q, Smith, Nikki, Dunfee, Rebecca L, Beard, Philippa M, Jagger, Brett W, Ligertwood, Yvonne, Hardisty, Gareth R, Xiao, Haixia, Benton, Donald J, Coburn, Alice M, Paulo, Joao A, Gygi, Steven P, McCauley, John W, Taubenberger, Jeffery K, Lycett, Samantha J, Weekes, Michael P, Dutia, Bernadette M, Digard, Paul

UNLABELLED: Two alleles of segment 8 (NS) circulate in nonchiropteran influenza A viruses. The A allele is found in avian and mammalian viruses, but the B allele is viewed as being almost exclusively found in avian viruses. This might reflect the fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______109::f776285e305e6f81a7edca984259a206
https://www.repository.cam.ac.uk/handle/1810/260668

The Role of the B-Allele of the Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

Autor: Turnbull, Matthew, Wise, Helen, Nicol, Marlynne, Smith, Nikki, Dunfee, Rebecca L, Beard, Philippa, Jagger, Brett W, Ligertwood, Yvonne, Hardisty, Gareth, Xiao, Haixia, Benton, Donald J, Coburn, Alice M, Paulo, Joao A, Gygi, Steven P, McCauley, John W, Taubenberger, Jeffery K., Lycett, Samantha, Weekes, Michael P, Dutia, Bernadette, Digard, Paul

Publikováno v: Turnbull, M, Wise, H, Nicol, M, Smith, N, Dunfee, R L, Beard, P, Jagger, B W, Ligertwood, Y, Hardisty, G, Xiao, H, Benton, D J, Coburn, A M, Paulo, J A, Gygi, S P, McCauley, J W, Taubenberger, J K, Lycett, S, Weekes, M P, Dutia, B & Digard, P 2016, ' The Role of the B-Allele of the Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity ', Journal of Virology, vol. 90, no. 20, pp. 9263-9284 . https://doi.org/10.1128/JVI.01205-16

Two ‘alleles' of segment 8 (NS) circulate in non-chiropteran influenza A viruses. The A-allele is found in avian and mammalian viruses, but the B-allele is viewed as almost exclusively avian. This might reflect that one or both of its encoded prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::98d192b58d4dda3986c741f97b1864af
https://www.pure.ed.ac.uk/ws/files/28306130/J._Virol._2016_Turnbull_9263_84.pdf

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