Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Duncheng Wang"'
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145179 (2015)
Autoimmune destruction of the pancreatic islets in Type 1 diabetes is mediated by both increased proinflammatory (Teff) and decreased regulatory (Treg) T lymphocytes resulting in a significant decrease in the Treg:Teff ratio. The non-obese diabetic (
Externí odkaz:
https://doaj.org/article/40bd2b0b85e74a0499aa76bc946e3f70
Autor:
Ashton E. Thomason, Debjani Ghosh, S. M. Touhidul Islam, Duncheng Wang, Cody D. Moorman, Daniel S. Wilkinson, Mark D. Mannie
Publikováno v:
The Journal of Immunology. 197:2992-3007
This study introduces a flexible format for tolerogenic vaccination that incorporates IFN-β and neuroantigen (NAg) in the Alum adjuvant. Tolerogenic vaccination required all three components, IFN-β, NAg, and Alum, for inhibition of experimental aut
Publikováno v:
Science China Life Sciences. 55:191-201
Grafting of methoxypoly(ethylene glycol) (mPEG) to cells and biomaterials is a promising non-pharmacological immunomodulation technology. However, due to the labile nature of cells, surface-plasma interactions are poorly understood; hence, a latex be
Publikováno v:
Biomaterials. 32:9494-9503
The induction of anergy or tolerance to prevent allorecognition is of clinical interest. To this end, the effects of methoxypoly(ethylene glycol) [mPEG] grafting to allogeneic lymphocytes on proliferation and phenotype (Th17 and Treg) was examined in
Publikováno v:
Science China Life Sciences. 54:589-598
Developing a practical means of reducing alloimmunization in chronically transfused patients would be of significant clinical benefit. Immunocamouflaging red blood cells (RBCs) by membrane grafting of methoxypoly(ethylene glycol) (mPEG) may reduce th
Autor:
Carol L. Claus, Paula Rajkumar, Marsela Braunstein, Amanda J. Moore, Duncheng Wang, Michele K. Anderson, Giovanna Vaccarelli
Publikováno v:
International Immunology. 22:963-972
Hematopoiesis is controlled by the interplay between transcription factors and environmental signals. One of the primary determinants of the T-lineage choice is Delta-like (DL)-Notch signaling, which promotes T-cell development and inhibits B-cell de
Autor:
Carol L. Claus, Amanda J. Moore, Marsela Braunstein, Michele K. Anderson, Mikael Sigvardsson, Duncheng Wang, Paula Rajkumar
Publikováno v:
The Journal of Immunology. 185:4109-4117
Hematopoietic development is controlled by combinatorial interactions between E-protein transcription factors and other lineage regulators that operate in the context of gene-regulatory networks. The E-proteins HEB and E2A are critical for T cell and
Publikováno v:
Transfusion. 50:1761-1765
BACKGROUND: Anti-glycophorin C (GPC), blood group antibodies of which cause hemolytic disease of the fetus and newborn (HDFN), is a potent inhibitor of erythroid progenitor cell growth. The cellular mechanism for growth inhibition has not been charac