Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Duncan X. Dobbins"'
Autor:
Uma R. Chandran, Duncan X. Dobbins, Michael Reynolds, Courtney Sabatelle, Sruti Shiva, Yashika S. Kamte, Kandarp M. Dave, Nidia Quillinan, Anisha D'Souza, Amelia Burch, Devika S. Manickam, Wanzhu Zhao, Paco S. Herson, Vishal Soman, Aravind Sreeram, Gina M. Joy
Publikováno v:
J Control Release
We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and to neurons in mi
Autor:
Kandarp M. Dave, Duncan X. Dobbins, Maura N. Farinelli, Abigail Sullivan, Jadranka Milosevic, Donna B. Stolz, Jeongyun Kim, Siyang Zheng, Devika S. Manickam
Publikováno v:
Cellular and molecular bioengineering. 15(5)
Extracellular vesicles (EVs) are promising carriers for the delivery of biotherapeutic cargo such as RNA and proteins. We have previously demonstrated that the innate EV mitochondria in microvesicles (MVs), but not exosomes (EXOs) can be transferred
Autor:
Kandarp M. Dave, Donna B. Stolz, Venugopal R. Venna, Victoria A. Quaicoe, Michael E. Maniskas, Michael John Reynolds, Riyan Babidhan, Duncan X. Dobbins, Maura N. Farinelli, Abigail Sullivan, Tarun N. Bhatia, Hannah Yankello, Rohan Reddy, Younsoo Bae, Rehana K. Leak, Sruti S. Shiva, Louise D. McCullough, Devika S Manickam
Ischemic stroke causes brain endothelial cell (BEC) death and damages tight junction integrity of the blood-brain barrier (BBB). We harnessed the innate mitochondrial load of endothelial cell-derived extracellular vesicles (EVs) and utilized mixtures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bd9baa88f4bdee3a273561f9c25437
https://doi.org/10.1101/2021.10.29.466491
https://doi.org/10.1101/2021.10.29.466491